DataSheet_2_Patient-Specific Assays Based on Whole-Genome Sequencing Data to Measure Residual Disease in Children With Acute Lymphoblastic Leukemia: A Proof of Concept Study.pdf by Cecilia Arthur (13002504)

“…All targets were readily detectable in a multiplexed ddPCR with minimal DNA input (1 ng of gDNA) at a 10⁻¹ dilution, and targets for half of the patients were also detectable at a 10⁻² dilution. …”

DataSheet_1_Balancing the Risk-Benefit Ratio of Immune Checkpoint Inhibitor and Anti-VEGF Combination Therapy in Renal Cell Carcinoma: A Systematic Review and Meta-Analysis.docx by Li Tao (154250)

“…The pooled risk ratio (RR) and 95% confidence intervals (CI) of AEs were calculated in the safety analysis.</p>Results<p>Six RCTs involving 4,227 patients were identified after a systematic search. …”

Data Sheet 1_Kinetic-pharmacodynamic model to predict post-rituximab B-cell repletion as a predictor of relapse in pediatric idiopathic nephrotic syndrome.docx by Ziwei Li (191878)

“…As a direct PD indicator, each 1-month increase of duration of B-cell depletion decreased risk of relapse by 21.4% (HR = 0.786; 95% CI: 0.635–0.972; p = 0.026). …”

Data_Sheet_1_Cognitive decline among older adults with heart diseases before and during the COVID-19 pandemic: A longitudinal cohort study.pdf by Rong Hua (325799)

Table_1_Dosimetric Evaluation of Commercially Available Flat vs. Self-Produced 3D-Conformal Silicone Boluses for the Head and Neck Region.xlsx by Stephan Pollmann (2821559)

“…Dose measurements for both types of boluses were performed with radiochromic films (EBT3) at three points per patient—at least one aimed to be in the high-dose area (scar) and one in the lower-dose area (spared healthy skin). …”

Table_1_Proteomic Analysis Reveals a Predominant NFE2L2 (NRF2) Signature in Canonical Pathway and Upstream Regulator Analysis of Leishmania-Infected Macrophages.xlsx by Juliana Perrone Bezerra de Menezes (6892616)

“…To evaluate the MØ responses to infection arising from these two Leishmania species, a proteomic study using a Multidimensional Protein Identification Technology (MudPIT) approach with liquid chromatography tandem mass spectrometry (LC-MS/MS) was carried out on CBA mice bone-marrow MØ (BMMØ). …”

DataSheet_1_Safety and Efficacy of Sintilimab and Anlotinib as First Line Treatment for Advanced Hepatocellular Carcinoma (KEEP-G04): A Single-Arm Phase 2 Study.docx by Xiaofeng Chen (392939)

“…</p>Methods and Materials<p>Pathologically-proven advanced HCC patients received sintilimab (200 mg) on day 1 and anlotinib (12 mg) once daily on days 1 to 14 every 3 weeks, with a safety run-in for the first six participants to assess dose-limiting toxicities (DLTs). …”

Presentation_1_NRG1, PIP4K2A, and HTR2C as Potential Candidate Biomarker Genes for Several Clinical Subphenotypes of Depression and Bipolar Disorder.zip by Anastasia Levchenko (9299687)

“…In the present study, the six genes were sequenced in a cohort of 19 patients with bipolar affective disorder, 41 patients with recurrent depressive disorder, and 55 patients with depressive episode. …”

DataSheet_1_High light stress under phosphorus limitation in summer may accelerate diatom shift from Skeletonema to Chaetoceros in an oligotrophic coastal area of Japan.docx by Ryoko Yano (14638847)

“…In our experiments, culture strains of Skeletonema costatum and Chaetoceros lorenzianus under severely nitrogen-limited conditions exhibited less non-photochemical quenching (NPQ) under prolonged exposure (1 h) to high light (800 µmol-photons m^-2 s^-1) and a decrease in photochemical quenching (qP) which was especially notable in S. costatum. …”

Data_Sheet_1_Age-specific disparity in insomnia among COVID-19 patients in Fangcang shelter hospitals: a population-based study in Shanghai, China.docx by Ruizi Shi (11603605)

“…</p>Methods<p>This cross-sectional study was conducted in the three largest Fangcang shelter hospitals during the lockdown period, from March to May 2022, in Shanghai. …”

Data_Sheet_1_Composition, interaction networks, and nitrogen metabolism patterns of bacterioplankton communities in a grassland type Lake: a case of Hulun Lake, China.docx by Yujiao Shi (5865263)

Data_Sheet_1_Global and regional prevalence of vitamin D deficiency in population-based studies from 2000 to 2022: A pooled analysis of 7.9 million participants.PDF by Aiyong Cui (12984401)

“…We found that globally, 15.7% (95% CrI 13.7–17.8), 47.9% (95% CrI 44.9–50.9), and 76·6% (95% CrI 74.0–79.1) of participants had serum 25-hydroxyvitamin D levels less than 30, 50, and 75 nmol/l, respectively; the prevalence slightly decreased from 2000–2010 to 2011–2022, but it was still at a high level; people living in high latitude areas had a higher prevalence; the prevalence in winter-spring was 1.7 (95% CrI 1.4–2.0) times that in summer-autumn; the Eastern Mediterranean region and Lower-middle-income countries had a higher prevalence; females were vulnerable to vitamin D deficiency; gender, sampling frame, detection assays, sampling region, time of data collection, season, and other factors contributed to heterogeneity between the included studies.…”

Data_Sheet_1_Annual Herbaceous Plants Exhibit Altered Morphological Traits in Response to Altered Precipitation and Drought Patterns in Semiarid Sandy Grassland, Northern China.doc... by Shan-Shan Sun (397346)

“…In this study, we examined the response of morphological traits of root, stem, leaf and reproduction meristems of annual herbaceous species to altered precipitation and drought patterns in a semiarid sandy grassland. The study involved a control treatment (100% of background precipitation) and the following six altered precipitation treatments: (1) P(+): precipitation increased by 30%, (2) P(++): precipitation increased by 60%, (3) P(-): precipitation decreased by 30%, (4) P(--): precipitation decreased by 60%, (5) drought 1 (D1): 46-day drought from May 1st to June 15th, and (6) drought 2 (D2): 46-day drought from July 1st to August 15th. …”

Data_Sheet_1_Resistant Soil Microbial Communities Show Signs of Increasing Phosphorus Limitation in Two Temperate Forests After Long-Term Nitrogen Addition.PDF by Stefan J. Forstner (8540784)

“…As a result, microbially-mediated decomposition might slow down, resulting in larger SOM pools with consequences for ecosystem nutrition and climate regulation. …”

Table1_Influence of Defects to Zr65Cu18Ni7Al10 Bulk Metallic Glass Properties Under Dynamic Compression.DOCX by C. Zhang (4455028)

Table_1_Silencing of Mitochondrial Trifunctional Protein A Subunit (HADHA) Increases Lipid Stores, and Reduces Oviposition and Flight Capacity in the Vector Insect Rhodnius prolixu... by Daniela S. Arêdes (8298873)

“…RhoprHadha deficiency resulted in higher triacylglycerol content and larger lipid droplets in the fat body during starvation. …”

Data_Sheet_1_Increasing N2200 Charge Transport Mobility to Improve Performance of All Polymer Solar Cells by Forming a Percolation Network Structure.docx by Ye Yan (4068706)

“…The μ_h/μ_e decrease from 16.9 to 1.53, causing a significant enhancement in the PCEs, from 5.87 to 8.28% without additives.…”

DataSheet1_The impact of agricultural machinery services on cultivated land productivity and its mechanisms: A case study of Handan city in the North China plain.docx by Yan Liu (25061)

“…The research findings are as follows. 1) AMS has a significantly positive impact on cultivated land productivity, and a heterogeneity analysis finds that the effects are larger for farmers with relatively less cultivated land and the marginal effects decrease as the adoption of AMS increases. 2) In various planting activities, AMS adoption in basic activities (e.g., ploughing, seeding, and harvesting) has positive effects on cultivated land productivity, while AMS adoption in management activities (e.g., fertilizing, irrigation, and pesticide spraying), has no obvious effect on cultivated land productivity. 3) According to the results of ATT, the conversion of non-adopting farmers to adopting AMS would increase cultivated land productivity by 7.6%–12.1%. 4) A mechanism analysis reveals that AMS adoption relieves financial constraints, improves technical efficiency, and increases smallholders’ crop yields. …”

Image_5_In Vitro Exposure of Primary Human T Cells and Monocytes to Polyclonal Stimuli Reveals a Basal Susceptibility to Display an Impaired Cellular Immune Response and Develop Se... by Rebeca Viurcos-Sanabria (12994449)

“…Then, we started a six-month follow-up and registered 12 participants who got SARS-CoV-2 infection, from whom we retrospectively analyzed the basal immune response pattern of T cells and monocytes. …”

Image_1_In Vitro Exposure of Primary Human T Cells and Monocytes to Polyclonal Stimuli Reveals a Basal Susceptibility to Display an Impaired Cellular Immune Response and Develop Se... by Rebeca Viurcos-Sanabria (12994449)

“…Then, we started a six-month follow-up and registered 12 participants who got SARS-CoV-2 infection, from whom we retrospectively analyzed the basal immune response pattern of T cells and monocytes. …”