Showing 681 - 700 results of 15,867 for search '(( six ((mean decrease) OR (a decrease)) ) OR ( i ((largest decrease) OR (larger decrease)) ))', query time: 0.94s Refine Results
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    High-throughput drug screen reveals HDAC and proteasome inhibitors as potent drug classes against synovial sarcoma. by Aimée N. Laporte (3617987)

    Published 2017
    “…Total score across the six cell lines was calculated out of 6. (D) IC<sub>50</sub> measurements were calculated for drug screen hits quisinostat (HDAC inhibitor), BGT-226 (PI3K/mTOR inhibitor), bortezomib (proteasome inhibitor) as compared with the current standard for synovial sarcoma treatment doxorubicin (cytotoxic DNA/RNA intercalating agent and topoisomerase inhibitor), in a panel of six human SS18-SSX positive cell lines and two control cell lines (HEK293T, MCF7). …”
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    Quisinostat-mediated HDAC inhibition results in a dissociation of the driving complex in synovial sarcoma. by Aimée N. Laporte (3617987)

    Published 2017
    “…<p>(A, B) Proximity ligation assay of SS18-SSX/TLE1 nuclear signal demonstrates a significant decrease in detectable protein co-localization following HDAC inhibition in SYO-1 synovial sarcoma cells. …”
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    RNA Interference in <em>Schistosoma mansoni</em> Schistosomula: Selectivity, Sensitivity and Operation for Larger-Scale Screening by Saša Štefanić (239531)

    Published 2010
    “…These findings and the operational parameters defined will facilitate larger RNAi screens.</p></div>…”
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