Prox1-mediated recruitment of LSD1/NuRD complex to <i>CYP7A1</i> promoter participates in bile acids induced repression of <i>CYP7A1</i>. by Huafang Ouyang (405865)

“…Normal mouse/rabbit IgG was used as non-specific control. Means and SD from three or six (ChIP using Prox1 and HDAC2 antibodies) independent experiments are presented. …”

(A and B) HEK293 cells were transfected with htt (1–208 aa) containing 23Q or 130Q and scFv-EM48 ( scFv) by Chuan-En Wang (48485)

“…The decreased MTS correlates with reduced cell viability. …”

Review and Analysis of Publication Trends over Three Decades in Three High Impact Medicine Journals by Alexander Ivanov (257155)

“…Studies were assessed for reporting COI.</p><p>Results</p><p>1,671 original articles were included in this analysis. …”

Efficacy of Handwashing with Soap and Nail Clipping on Intestinal Parasitic Infections in School-Aged Children: A Factorial Cluster Randomized Controlled Trial by Mahmud Abdulkader Mahmud (751966)

“…The next essential step should be implementing pragmatic studies and developing more effective approaches to promote and implement handwashing with soap and nail clipping at larger scales.</p></div>…”

Application of Multiplexed Ion Mobility MS for Identification of Protein Signatures of Treatment of Tuberculosis (Cascadia proteomics symposium 2017) by PNNL Omics (4106851)

“…Liquid Chromatography - Ion Mobility MS (LC-IM-MS) provides a robust tool to analyze larger patient cohorts with necessary sensitivity to capture the global proteome. …”

Table_2_Cellular Mechanisms Underlying B Cell Abnormalities in Patients With Gain-of-Function Mutations in the PIK3CD Gene.docx by Wenjie Wang (413433)

“…</p>Conclusions<p>The present study suggests additional mechanistic insight into B cell pathology of APDS: (1) decreased peripheral B cell numbers may be due to the increased death of naïve B cells; (2) larger B cell sizes and expanded DNB population suggest enhanced activation and differentiation of naïve B cells into DNB cells; (3) the impaired CSR yet normal PB differentiation can predominantly generate IgM-secreting cells, resulting in elevated IgM levels.…”

Ticagrelor treatment, but not clopidogrel treatment, induces the praroxonase-1 (PON1) message, increases tissue and serum PON1 protein, and mitigates atherosclerosis. by Hasseri Halim (6883436)

“…Fifty-six genes were concordantly and differentially expressed in both CLO/CTL and TIC/CTL groups, of which 48 genes were concordantly upregulated and 8 concordantly downregulated in both groups. …”

Table_2_Characterization of Non-hormone Expressing Endocrine Cells in Fetal and Infant Human Pancreas.DOCX by Abu Saleh Md Moin (6189512)

“…While the majority of CPHN cells express (in overall compartments of pancreas) the pan-endocrine transcription factor NKX2.2 and beta-cell specific NKX6.1 in comparable frequency in fetal and infant/child cases (81.9 ± 6.3 vs. 82.8 ± 3.8% NKX6.1⁺-CPHN cells of total CPHN cells, fetal vs. infant/child, p = 0.9; 88.0 ± 4.7 vs. 82.1 ± 5.3% NKX2.2⁺-CPHN cells of total CPHN cells, fetal vs. infant/child, p = 0.4), the frequency of clustered CPHN cells expressing NKX6.1 or NKX2.2 is lower in infant/child vs. fetal cases (1.2 ± 0.3 vs. 16.7 ± 4.7 clustered NKX6.1⁺-CPHN cells/mm², infant/child vs. fetal, p < 0.01; 2.7 ± 1.0 vs. 16.0 ± 4.0 clustered NKX2.2⁺-CPHN cells/mm², infant/child vs. fetal, p < 0.01).…”

Image_4_Characterization of Non-hormone Expressing Endocrine Cells in Fetal and Infant Human Pancreas.jpg by Abu Saleh Md Moin (6189512)

“…While the majority of CPHN cells express (in overall compartments of pancreas) the pan-endocrine transcription factor NKX2.2 and beta-cell specific NKX6.1 in comparable frequency in fetal and infant/child cases (81.9 ± 6.3 vs. 82.8 ± 3.8% NKX6.1⁺-CPHN cells of total CPHN cells, fetal vs. infant/child, p = 0.9; 88.0 ± 4.7 vs. 82.1 ± 5.3% NKX2.2⁺-CPHN cells of total CPHN cells, fetal vs. infant/child, p = 0.4), the frequency of clustered CPHN cells expressing NKX6.1 or NKX2.2 is lower in infant/child vs. fetal cases (1.2 ± 0.3 vs. 16.7 ± 4.7 clustered NKX6.1⁺-CPHN cells/mm², infant/child vs. fetal, p < 0.01; 2.7 ± 1.0 vs. 16.0 ± 4.0 clustered NKX2.2⁺-CPHN cells/mm², infant/child vs. fetal, p < 0.01).…”

Image_7_Characterization of Non-hormone Expressing Endocrine Cells in Fetal and Infant Human Pancreas.jpg by Abu Saleh Md Moin (6189512)

“…While the majority of CPHN cells express (in overall compartments of pancreas) the pan-endocrine transcription factor NKX2.2 and beta-cell specific NKX6.1 in comparable frequency in fetal and infant/child cases (81.9 ± 6.3 vs. 82.8 ± 3.8% NKX6.1⁺-CPHN cells of total CPHN cells, fetal vs. infant/child, p = 0.9; 88.0 ± 4.7 vs. 82.1 ± 5.3% NKX2.2⁺-CPHN cells of total CPHN cells, fetal vs. infant/child, p = 0.4), the frequency of clustered CPHN cells expressing NKX6.1 or NKX2.2 is lower in infant/child vs. fetal cases (1.2 ± 0.3 vs. 16.7 ± 4.7 clustered NKX6.1⁺-CPHN cells/mm², infant/child vs. fetal, p < 0.01; 2.7 ± 1.0 vs. 16.0 ± 4.0 clustered NKX2.2⁺-CPHN cells/mm², infant/child vs. fetal, p < 0.01).…”

Table_3_Characterization of Non-hormone Expressing Endocrine Cells in Fetal and Infant Human Pancreas.DOCX by Abu Saleh Md Moin (6189512)

“…While the majority of CPHN cells express (in overall compartments of pancreas) the pan-endocrine transcription factor NKX2.2 and beta-cell specific NKX6.1 in comparable frequency in fetal and infant/child cases (81.9 ± 6.3 vs. 82.8 ± 3.8% NKX6.1⁺-CPHN cells of total CPHN cells, fetal vs. infant/child, p = 0.9; 88.0 ± 4.7 vs. 82.1 ± 5.3% NKX2.2⁺-CPHN cells of total CPHN cells, fetal vs. infant/child, p = 0.4), the frequency of clustered CPHN cells expressing NKX6.1 or NKX2.2 is lower in infant/child vs. fetal cases (1.2 ± 0.3 vs. 16.7 ± 4.7 clustered NKX6.1⁺-CPHN cells/mm², infant/child vs. fetal, p < 0.01; 2.7 ± 1.0 vs. 16.0 ± 4.0 clustered NKX2.2⁺-CPHN cells/mm², infant/child vs. fetal, p < 0.01).…”

Image_5_Characterization of Non-hormone Expressing Endocrine Cells in Fetal and Infant Human Pancreas.jpg by Abu Saleh Md Moin (6189512)

“…While the majority of CPHN cells express (in overall compartments of pancreas) the pan-endocrine transcription factor NKX2.2 and beta-cell specific NKX6.1 in comparable frequency in fetal and infant/child cases (81.9 ± 6.3 vs. 82.8 ± 3.8% NKX6.1⁺-CPHN cells of total CPHN cells, fetal vs. infant/child, p = 0.9; 88.0 ± 4.7 vs. 82.1 ± 5.3% NKX2.2⁺-CPHN cells of total CPHN cells, fetal vs. infant/child, p = 0.4), the frequency of clustered CPHN cells expressing NKX6.1 or NKX2.2 is lower in infant/child vs. fetal cases (1.2 ± 0.3 vs. 16.7 ± 4.7 clustered NKX6.1⁺-CPHN cells/mm², infant/child vs. fetal, p < 0.01; 2.7 ± 1.0 vs. 16.0 ± 4.0 clustered NKX2.2⁺-CPHN cells/mm², infant/child vs. fetal, p < 0.01).…”

Table_4_Characterization of Non-hormone Expressing Endocrine Cells in Fetal and Infant Human Pancreas.DOCX by Abu Saleh Md Moin (6189512)

“…While the majority of CPHN cells express (in overall compartments of pancreas) the pan-endocrine transcription factor NKX2.2 and beta-cell specific NKX6.1 in comparable frequency in fetal and infant/child cases (81.9 ± 6.3 vs. 82.8 ± 3.8% NKX6.1⁺-CPHN cells of total CPHN cells, fetal vs. infant/child, p = 0.9; 88.0 ± 4.7 vs. 82.1 ± 5.3% NKX2.2⁺-CPHN cells of total CPHN cells, fetal vs. infant/child, p = 0.4), the frequency of clustered CPHN cells expressing NKX6.1 or NKX2.2 is lower in infant/child vs. fetal cases (1.2 ± 0.3 vs. 16.7 ± 4.7 clustered NKX6.1⁺-CPHN cells/mm², infant/child vs. fetal, p < 0.01; 2.7 ± 1.0 vs. 16.0 ± 4.0 clustered NKX2.2⁺-CPHN cells/mm², infant/child vs. fetal, p < 0.01).…”

Image_6_Characterization of Non-hormone Expressing Endocrine Cells in Fetal and Infant Human Pancreas.jpg by Abu Saleh Md Moin (6189512)

“…While the majority of CPHN cells express (in overall compartments of pancreas) the pan-endocrine transcription factor NKX2.2 and beta-cell specific NKX6.1 in comparable frequency in fetal and infant/child cases (81.9 ± 6.3 vs. 82.8 ± 3.8% NKX6.1⁺-CPHN cells of total CPHN cells, fetal vs. infant/child, p = 0.9; 88.0 ± 4.7 vs. 82.1 ± 5.3% NKX2.2⁺-CPHN cells of total CPHN cells, fetal vs. infant/child, p = 0.4), the frequency of clustered CPHN cells expressing NKX6.1 or NKX2.2 is lower in infant/child vs. fetal cases (1.2 ± 0.3 vs. 16.7 ± 4.7 clustered NKX6.1⁺-CPHN cells/mm², infant/child vs. fetal, p < 0.01; 2.7 ± 1.0 vs. 16.0 ± 4.0 clustered NKX2.2⁺-CPHN cells/mm², infant/child vs. fetal, p < 0.01).…”

Image_2_Characterization of Non-hormone Expressing Endocrine Cells in Fetal and Infant Human Pancreas.jpg by Abu Saleh Md Moin (6189512)

“…While the majority of CPHN cells express (in overall compartments of pancreas) the pan-endocrine transcription factor NKX2.2 and beta-cell specific NKX6.1 in comparable frequency in fetal and infant/child cases (81.9 ± 6.3 vs. 82.8 ± 3.8% NKX6.1⁺-CPHN cells of total CPHN cells, fetal vs. infant/child, p = 0.9; 88.0 ± 4.7 vs. 82.1 ± 5.3% NKX2.2⁺-CPHN cells of total CPHN cells, fetal vs. infant/child, p = 0.4), the frequency of clustered CPHN cells expressing NKX6.1 or NKX2.2 is lower in infant/child vs. fetal cases (1.2 ± 0.3 vs. 16.7 ± 4.7 clustered NKX6.1⁺-CPHN cells/mm², infant/child vs. fetal, p < 0.01; 2.7 ± 1.0 vs. 16.0 ± 4.0 clustered NKX2.2⁺-CPHN cells/mm², infant/child vs. fetal, p < 0.01).…”

Image_8_Characterization of Non-hormone Expressing Endocrine Cells in Fetal and Infant Human Pancreas.jpg by Abu Saleh Md Moin (6189512)

“…While the majority of CPHN cells express (in overall compartments of pancreas) the pan-endocrine transcription factor NKX2.2 and beta-cell specific NKX6.1 in comparable frequency in fetal and infant/child cases (81.9 ± 6.3 vs. 82.8 ± 3.8% NKX6.1⁺-CPHN cells of total CPHN cells, fetal vs. infant/child, p = 0.9; 88.0 ± 4.7 vs. 82.1 ± 5.3% NKX2.2⁺-CPHN cells of total CPHN cells, fetal vs. infant/child, p = 0.4), the frequency of clustered CPHN cells expressing NKX6.1 or NKX2.2 is lower in infant/child vs. fetal cases (1.2 ± 0.3 vs. 16.7 ± 4.7 clustered NKX6.1⁺-CPHN cells/mm², infant/child vs. fetal, p < 0.01; 2.7 ± 1.0 vs. 16.0 ± 4.0 clustered NKX2.2⁺-CPHN cells/mm², infant/child vs. fetal, p < 0.01).…”

Image_3_Characterization of Non-hormone Expressing Endocrine Cells in Fetal and Infant Human Pancreas.jpg by Abu Saleh Md Moin (6189512)

“…While the majority of CPHN cells express (in overall compartments of pancreas) the pan-endocrine transcription factor NKX2.2 and beta-cell specific NKX6.1 in comparable frequency in fetal and infant/child cases (81.9 ± 6.3 vs. 82.8 ± 3.8% NKX6.1⁺-CPHN cells of total CPHN cells, fetal vs. infant/child, p = 0.9; 88.0 ± 4.7 vs. 82.1 ± 5.3% NKX2.2⁺-CPHN cells of total CPHN cells, fetal vs. infant/child, p = 0.4), the frequency of clustered CPHN cells expressing NKX6.1 or NKX2.2 is lower in infant/child vs. fetal cases (1.2 ± 0.3 vs. 16.7 ± 4.7 clustered NKX6.1⁺-CPHN cells/mm², infant/child vs. fetal, p < 0.01; 2.7 ± 1.0 vs. 16.0 ± 4.0 clustered NKX2.2⁺-CPHN cells/mm², infant/child vs. fetal, p < 0.01).…”

Image_9_Characterization of Non-hormone Expressing Endocrine Cells in Fetal and Infant Human Pancreas.jpg by Abu Saleh Md Moin (6189512)

“…While the majority of CPHN cells express (in overall compartments of pancreas) the pan-endocrine transcription factor NKX2.2 and beta-cell specific NKX6.1 in comparable frequency in fetal and infant/child cases (81.9 ± 6.3 vs. 82.8 ± 3.8% NKX6.1⁺-CPHN cells of total CPHN cells, fetal vs. infant/child, p = 0.9; 88.0 ± 4.7 vs. 82.1 ± 5.3% NKX2.2⁺-CPHN cells of total CPHN cells, fetal vs. infant/child, p = 0.4), the frequency of clustered CPHN cells expressing NKX6.1 or NKX2.2 is lower in infant/child vs. fetal cases (1.2 ± 0.3 vs. 16.7 ± 4.7 clustered NKX6.1⁺-CPHN cells/mm², infant/child vs. fetal, p < 0.01; 2.7 ± 1.0 vs. 16.0 ± 4.0 clustered NKX2.2⁺-CPHN cells/mm², infant/child vs. fetal, p < 0.01).…”

A study of the abundance of species in grassland-to-pond transition zone and impermeable ground habitats by Helen Musulan (3119433)

“…Trees were counted every two meters within 0.5 m of the transect. Only trees larger than 1.5 meters in height were counted. Having a height requirement decreased the probability of counting a non-woody plant. …”

Surgical Versus Non-Surgical Treatment for Vertebral Compression Fracture with Osteopenia: A Systematic Review and Meta-Analysis by Jia-Bao Guo (746660)

“…Evidence of better quality and from a larger sample size is required before a recommendation can be made.…”