Frequency distribution of primary hit structural clusters. by Elizabeth R. Sharlow (202360)

“…After analyses, 553 structural clusters were identified with cluster sizing ranging from 2–360 compounds. Six hundred and forty compounds could not be assigned to a structural cluster and were classified as singletons.…”

Deletion of <i>pafr</i> reduces tactile allodynia. by Shigeo Hasegawa (249454)

“…<p>While wild-type mice with an L5 nerve injury showed a progressively decreased paw withdrawal threshold, <i>pafr</i>^−/− mice showed an attenuation of the decrease in paw withdrawal threshold after nerve injury. …”

Zebrafish Bone and General Physiology Are Differently Affected by Hormones or Changes in Gravity by Jessica Aceto (752869)

“…Finally, we propose a novel type of experimental approach, the "Reduced Gravity Paradigm", by keeping the developing larvae at 3g hypergravity for the first 5 days before returning them to 1g for one additional day. 5 days exposure to 3g during these early stages also caused increased bone formation, while gene expression analysis revealed a central network of regulatory genes (<i>hes5</i>, <i>sox10</i>, <i>lgals3bp</i>, <i>egr1</i>, <i>edn1</i>, <i>fos</i>, <i>fosb</i>, <i>klf2</i>, <i>gadd45ba</i> and <i>socs3a</i>) whose expression was consistently affected by the transition from hyper- to normal gravity.…”

Phosphorylation of PKA targets is greatest when PKA is colocalized with cAMP production either in the spine or in the dendrite. by Myungsook Kim (2166613)

“…<p>(A1) Phospho-inhibitor-1 is greatest when PKA is colocalized with adenylyl cyclase (AC) in the spine head (red trace) and second largest when PKA is colocalized with AC in the dendrite (green trace). …”

Auto-antibodies in serum correlate with DTI and cognitive changes. by Nicola Marchi (4967)

“…<p><b>A</b>) Mean diffusivity index expressed as percent of white matter voxels showing either significant increase or decrease in MD between the preseason and 6 months after the post-season. …”

Migrants, healthy worker effect, and mortality trends in the Gulf Cooperation Council countries by Karima Chaabna (785895)

“…In 1990–2015, all-cause age-standardized mortality was inversely proportional to national population size (<i>p</i>-values: 0.0001–0.0457). In Bahrain, Qatar, Oman, and Saudi Arabia, the highest annual decrease in mortality was observed when the annual population growth was the highest. …”

Transforming Growth Factor β Signaling Overcomes Dasatinib Resistance in Lung Cancer by Edna Gordian (673369)

“…Knockdown of the expression of Smad3 using Smad3 siRNA also resulted in a decrease in BIM protein, suggesting that TGFβ-1 + dasatinib-induced apoptosis is mediated by Smad3 regulation of BIM. …”

Adaptive radiotherapy for head and neck cancer by J. Castelli (5823164)

“…</p> <p><b>Results:</b> Eight <i>in silico</i> studies tested a number of replanning sessions, ranging from 1 to 6, aiming primarily to reduce the dose to the parotid glands. …”

Frontal crash seat belt restraint effectiveness and comfort accessories used by older occupants by Tom Whyte (3911467)

“…</p> <p><b>Methods:</b> Eight frontal sled tests (43 km/h, 32 <i>g</i>) were carried out on a deceleration sled fitted with a three-point lap-sash seat belt and a front passenger seat from a common Australian passenger car for each test. …”

Impact On Local Pearl Oyster Pinctada Radiata Exposed To Chronic Levels Of Chlorine by Alfaqih, Arwa Shaif

“…In addition, when transfer the oysters from its natural ecosystem to artificial one, outdoors affect in the laboratory as temperature, light; all lead to stress and decreasing in the physiological performance of oysters. …”
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Effects of perturbation of Notch signaling in MG-derived neurospheres assays. by Carolina Beltrame Del Debbio (243080)

“…<i>Hes1</i> transcripts levels (f) increased and decreased in the presence of Jag1 and DAPT, respectively, compared to controls, confirming perturbation of Notch signaling. …”

Supplementary Material for: Increased Neuronal Nuclear and Perikaryal Size in the Medial Mamillary Nucleus of Vascular Dementia and Alzheimer’s Disease Patients: Relation to Nuclea... by Ishunina T.A. (4119157)

“…Neuronal nuclei (<i>p</i> < 0.05), but not perikarya were larger in AD than in control patients. …”

Within-host model fitness and equilibrium viral load. by Harriet Longley (22756119)

“…We explore a range of values of <i>m</i> (ranging 10 to 400 in increments of 10), with the corresponding fitness cost of a mutation reducing on a log-linear scale as <i>m</i> increases. …”

Activity traces and changes in individual β-galactosidase molecules between heat pulses. by Marcin J. Rojek (511810)

“…Negative values correspond to a decrease in the activity and positive values correspond to an increase in the activity after a heat pulse. …”

Supplementary information files for The relationship between bowling intensity and ground reaction force in cricket pace bowlers by Joseph W McGrath (14649929)

“…Lastly, bowling at submaximal intensities (i.e., low–medium) was associated with larger decreases in peak horizontal force (7.9–12.3% decrease), impulse (15.8–21.4%) and loading rate (7.4–12.7%) compared to decreases in ball release speed (5.4–8.3%). …”

DataSheet2_Micro-Porosity and gas emission characteristics of thermally contacted metamorphic coal by igneous intrusion.PDF by Xiang Fu (714580)

“…The results show that the porosity of macro- and meso-pores and the number of pores in the metamorphic coal are larger than those of the normal coal. The total length of pores per unit area and the average shape factor increase, and the connectivity of pore is raised, resulting in an enhanced gas release capacity (increased V₁) within the first one second. …”

DataSheet3_Micro-Porosity and gas emission characteristics of thermally contacted metamorphic coal by igneous intrusion.PDF by Xiang Fu (714580)

“…The results show that the porosity of macro- and meso-pores and the number of pores in the metamorphic coal are larger than those of the normal coal. The total length of pores per unit area and the average shape factor increase, and the connectivity of pore is raised, resulting in an enhanced gas release capacity (increased V₁) within the first one second. …”

MPP2 expression levels influence mIPSC amplitudes. by Bettina Schmerl (669003)

“…<b>(e)</b> Knockdown of MPP2 leads to a decrease in average mIPSC amplitude (Mann–Whitney test <i>p</i> = 0.0277). …”

ZnO−Al₂O₃ and ZnO−TiO₂ Core−Shell Nanowire Dye-Sensitized Solar Cells by Matt Law (1296396)

“…We find that alumina shells of all thicknesses act as insulating barriers that improve cell open-circuit voltage (<i>V</i>_OC) only at the expense of a larger decrease in short-circuit current density (<i>J</i>_SC). …”

Internal nitrogen removal from sediments by the hybrid system of microbial fuel cells and submerged aquatic plants by Peng Xu (17962)

“…The smaller number of <i>Nitrospira</i> and the larger number of <i>Bacillus</i> and <i>Pseudomonas</i> on the anodes via high throughput sequencing may account for strong mineralization and denitrification in the sediments under closed-circuit. …”