Table 1_Optimal fertilizer rate and sowing density can improve oat quality, yield and N and P comprehensive efficiency in the Loess Plateau of China.docx by Ruochen Zhang (3434996)

“…Introduction<p>Oat is a nutritious native species in Loess Plateau for forage and animal husbandry. …”

DataSheet_1_Reducedhumoral response against variants of concern in childhood solid cancer patients compared to adult patients and healthy children after SARS-CoV-2 vaccination.docx by Yifei Ma (206062)

“…Introduction<p>Although there is extended research on the response to severe acute respiratory syndrome coronavirus 2 (SARS-CoV-2) vaccines in adult cancer patients (ACP), the immunogenicity to the variants of concern (VOCs) in childhood cancer patients (CCP) and safety profiles are now little known.</p>Methods<p>A prospective, multi-center cohort study was performed by recruiting children with a solid cancer diagnosis and childhood healthy control (CHC) to receive standard two-dose SARS-CoV-2 vaccines. …”

Rer1 loss reduces γ-secretase activity, leading to abnormal Notch signaling and neural stem cell proliferation. by Taichi Hara (46246)

“…<p>(A) Reduced γ-secretase activity in forebrain-specific Rer1 cKO mice. γ-Secretase activity was assayed in solubilized membrane fractions of cerebral cortex isolated from control and forebrain-specific Rer1 cKO mice on E18.5. …”

DataSheet_1_Investigation of the Lipid-Lowering Mechanisms and Active Ingredients of Danhe Granule on Hyperlipidemia Based on Systems Pharmacology.docx by Kuikui Chen (8801588)

“…Experimental results indicated that DHG significantly increased SREBP-2, LDLR, PPARα, liver X receptor alpha (LXRα), cholesterol 7α-hydroxylase (CYP7A1), and ATP binding cassette subfamily A member 1 (ABCA1) mRNA and protein expressions while decreased SREBP-1c and fatty acid synthase (FAS) mRNA, and protein expressions.…”

DataSheet1_Antitumor Effect of Fluoxetine on Chronic Stress-Promoted Lung Cancer Growth via Suppressing Kynurenine Pathway and Enhancing Cellular Immunity.ZIP by Zhen Yang (107412)

“…FLX promoted Th to differentiate into Th1 cells and increased IL-2 and IFN-γ, meanwhile inhibited Th differentiate into Th2 and Th17 cells and decreased the concentrations of IL-4, IL-6, IL-10, and IL-17A. …”

DataSheet_2_Investigation of the Lipid-Lowering Mechanisms and Active Ingredients of Danhe Granule on Hyperlipidemia Based on Systems Pharmacology.pdf by Kuikui Chen (8801588)

“…Experimental results indicated that DHG significantly increased SREBP-2, LDLR, PPARα, liver X receptor alpha (LXRα), cholesterol 7α-hydroxylase (CYP7A1), and ATP binding cassette subfamily A member 1 (ABCA1) mRNA and protein expressions while decreased SREBP-1c and fatty acid synthase (FAS) mRNA, and protein expressions.…”

DPP6 regulates a channel with properties similar to TASK-3. by Brian M. Nadin (401054)

“…For these studies we only characterized changes in input conductance because pH 6.0 partially blocks voltage gated channels Na⁺ channels, making an analysis of effects of low pH on firing threshold complex and essentially uninformative for our purposes <a href="http://www.plosone.org/article/info:doi/10.1371/journal.pone.0060831#pone.0060831-Hille1" target="_blank">[73]</a>. Control cells show much larger voltage responses following low pH application indicating that a significant fraction of the resting membrane conductance is pH sensitive. …”

Data_Sheet_1_Adherence to COVID-19 preventive measures in Sub-Saharan Africa during the 1st year of the pandemic: Pooled analysis of the International Citizen Project on COVID-19 (... by Leonard Ngarka (6036032)

“…Using linear mixed models, predictors of increased individual adherence included: higher age (Coef = 0.005; 95% CI: 0.003–0.007), female gender (Coef = 0.071; 95% CI: 0.039–0.104), higher educational level (Coef = 0.999; 95% CI: 0.885–1.113), and working in the healthcare sector (Coef = 0.418; 95% CI: 0.380–0.456).</p>Conclusion<p>Decreasing adherence to non-pharmaceutical measures over time constitutes a risk for the persistence of COVID-19 in SSA. …”

Data_Sheet_1_Intracellular Vesicle Trafficking Genes, RabC-GTP, Are Highly Expressed Under Salinity and Rapid Dehydration but Down-Regulated by Drought in Leaves of Chickpea (Cicer... by Gulmira Khassanova (5796401)

“…Five isoforms of the CaRabC gene were identified and studied: CaRabC-1a, -1b, -1c, -2a and -2a^∗. Six accessions of both Desi and Kabuli ecotypes, selected from field trials, were tested for tolerance to abiotic stresses, including salinity, drought and rapid dehydration and compared to plant growth under control conditions. …”

Alternations of L-type calcium channel transcripts, protein, and action potential in KO smooth muscle. by Moon Young Lee (749843)

“…<p>(A) PCR validation of alternatively started and spliced exons of <i>Cacna1c</i> in WT and KO jejunum smooth muscle at KO days 5, 10, and 15. …”

Data_Sheet_1_The efficacy and safety of Chinese herbal medicine as an add-on therapy for amyotrophic lateral sclerosis: An updated systematic review and meta-analysis of randomized... by Yingdi Liao (13918467)

“…</p>Methods<p>We searched six electronic databases for randomized controlled trials involving CHM and patients with ALS that were published up to April 2022. …”

Table_1_Lipopolysaccharide-induced immune stress negatively regulates broiler chicken growth via the COX-2-PGE2-EP4 signaling pathway.docx by Kexin Liu (1547230)

“…However, the underlying mechanisms that cause growth inhibition of broilers with immune stress are not well defined.</p>Methods<p>A total of 252 1-day-old Arbor Acres(AA) broilers were randomly allocated to three groups with six replicates per group and 14 broilers per replicate. …”

Therapeutic body wraps (TBW) for treatment of severe injurious behaviour in children with autism spectrum disorder (ASD): A 3-month randomized controlled feasibility study by Pierre Delion (5470502)

“…There was no difference between wet and dry TBW at 3 months, and ABC-irritability significantly decreased with both wet and dry sheet TBW. To assess whether TBW may constitute an alternative to medication or behavioural intervention for treating SIB in ASD patients, a larger randomized comparative trial (e.g. …”

Assays showing functional activity of the aging genes. by Dror Sagi (156783)

“…<p>a. Levels of total ATP in extracts from L4 stage hermaphrodites. …”

Table_1_Bacteriophage as an Alternative to Antibiotics Promotes Growth Performance by Regulating Intestinal Inflammation, Intestinal Barrier Function and Gut Microbiota in Weaned P... by Yongdi Zeng (10040807)

“…<p>This study aimed to investigate the effects of dietary bacteriophage supplementation on growth performance, intestinal morphology, barrier function, and intestinal microbiota of weaned piglets fed antibiotic-free diet. A total of 120 weaned piglets were allotted to four dietary treatments with five pens/treatment and six piglets/pen in a 21-d feeding trial. …”

DataSheet2_Polymorphisms of nucleotide excision repair genes associated with colorectal cancer risk: Meta-analysis and trial sequential analysis.docx by Chuncheng Yi (10324538)

“…It showed that excision and repair cross complementary group 1 (ERCC1) rs11615 CC genotype decreased the risk of CRC, compared with TT genotype (CC vs. …”

DataSheet3_Polymorphisms of nucleotide excision repair genes associated with colorectal cancer risk: Meta-analysis and trial sequential analysis.docx by Chuncheng Yi (10324538)

“…It showed that excision and repair cross complementary group 1 (ERCC1) rs11615 CC genotype decreased the risk of CRC, compared with TT genotype (CC vs. …”

Table_1_Real-world effectiveness and persistence of secukinumab in the treatment of patients with psoriatic arthritis.DOCX by Juan José Alegre-Sancho (15457829)

“…</p>Conclusion<p>Secukinumab showed long-term effectiveness across the six key PsA domains thus reducing disease activity and pain, which are major treatment goals. …”

Image_2_An updated management approach of Pompe disease patients with high-sustained anti-rhGAA IgG antibody titers: experience with bortezomib-based immunomodulation.jpeg by Ankit K. Desai (9214082)

“…</p>Methods<p>Here, we describe two IOPD cases (patients 6 and 8) who developed HSAT at 8 and 10 weeks on ERT despite transient low-dose methotrexate ITI administration in the ERT-naïve setting and were treated with a bortezomib-based ITI regimen, and we compare their courses to a series of six historical patients (patients 1-5, and 7) with a similar presentation who exemplify our evolving approach to treatment.…”

Image_1_An updated management approach of Pompe disease patients with high-sustained anti-rhGAA IgG antibody titers: experience with bortezomib-based immunomodulation.jpeg by Ankit K. Desai (9214082)

“…</p>Methods<p>Here, we describe two IOPD cases (patients 6 and 8) who developed HSAT at 8 and 10 weeks on ERT despite transient low-dose methotrexate ITI administration in the ERT-naïve setting and were treated with a bortezomib-based ITI regimen, and we compare their courses to a series of six historical patients (patients 1-5, and 7) with a similar presentation who exemplify our evolving approach to treatment.…”