Table_2_Radiation therapy induces immunosenescence mediated by p90RSK.xlsx by Masaki Imanishi (515835)

“…We found that the frequency of the B cell subtype was decreased after RT. Unsupervised clustering of the CyTOF data identified 138 functional subsets of PBMCs. …”

Carbon trading, co-pollutants, and environmental equity: Evidence from California’s cap-and-trade program (2011–2015) by Lara Cushing (2914064)

“…</p><p>Methods and findings</p><p>We examined the relationship between multiple measures of neighborhood disadvantage and the location of GHG and co-pollutant emissions from facilities regulated under California’s cap-and-trade program—the world’s fourth largest operational carbon trading program. We examined temporal patterns in annual average emissions of GHGs, particulate matter (PM_2.5), nitrogen oxides, sulfur oxides, volatile organic compounds, and air toxics before (January 1, 2011–December 31, 2012) and after (January 1, 2013–December 31, 2015) the initiation of carbon trading. …”

Data_Sheet_2_Putative Concussion Biomarkers Identified in Adolescent Male Athletes Using Targeted Plasma Proteomics.PDF by Michael R. Miller (375187)

“…Proximity extension assays were performed for 1,472 plasma proteins; a total of six proteins were considered significantly different between cohorts (P < 0.01; five proteins decreased and one protein increased). …”

The Genotypic Population Structure of <em>Mycobacterium tuberculosis</em> Complex from Moroccan Patients Reveals a Predominance of Euro-American Lineages by Ouafae Lahlou (127724)

“…</p> <h3>Conclusion</h3><p>The <em>M. tuberculosis</em> population structure in Morocco is highly homogeneous, and is characterized by the predominance of the Euro-American lineages, namely LAM, Haarlem, and T, which belong to the “evolutionary recent” TbD1−/PGG2/3 phylogenetic group. The combination of spoligotyping and MIRUs decreased the clustering rate significantly, and should now be systematically applied in larger studies. …”

Image_2_Acute MR-Guided High-Intensity Focused Ultrasound Lesion Assessment Using Diffusion-Weighted Imaging and Histological Analysis.TIF by Matthew R. Walker (7434794)

“…</p><p>Results: The volume of treated tissue measured via MDWI did not differ significantly from histological measurements, and both were significantly larger than the treatment cell volume. Diffusion metrics in the treatment region were significantly decreased following MRgFUS treatment, with the peak change seen at the lesion core and decreasing radially. …”

Table2_Exploring the causal relationship: bidirectional mendelian randomization study on benign prostatic hyperplasia and cardiovascular diseases.XLSX by Nanyan Xiang (18124306)

“…</p>Results<p>Using a bidirectional two-sample MR study, we found that BPH patients had an increased risk of developing CHD (ConMix OR = 1.152, 95% CI: 1.011–1.235, p = 0.035) and MI (ConMix OR = 1.107.95% CI: 1.022–1.164, p = 0.013), but a decreased risk of stroke (ConMix OR = 0.872, 95% CI: 0.797–0.926, p = 0.002). …”

Table3_Exploring the causal relationship: bidirectional mendelian randomization study on benign prostatic hyperplasia and cardiovascular diseases.XLSX by Nanyan Xiang (18124306)

“…</p>Results<p>Using a bidirectional two-sample MR study, we found that BPH patients had an increased risk of developing CHD (ConMix OR = 1.152, 95% CI: 1.011–1.235, p = 0.035) and MI (ConMix OR = 1.107.95% CI: 1.022–1.164, p = 0.013), but a decreased risk of stroke (ConMix OR = 0.872, 95% CI: 0.797–0.926, p = 0.002). …”

Table4_Exploring the causal relationship: bidirectional mendelian randomization study on benign prostatic hyperplasia and cardiovascular diseases.XLSX by Nanyan Xiang (18124306)

“…</p>Results<p>Using a bidirectional two-sample MR study, we found that BPH patients had an increased risk of developing CHD (ConMix OR = 1.152, 95% CI: 1.011–1.235, p = 0.035) and MI (ConMix OR = 1.107.95% CI: 1.022–1.164, p = 0.013), but a decreased risk of stroke (ConMix OR = 0.872, 95% CI: 0.797–0.926, p = 0.002). …”

Analysis of Differential miRNA Expression in the Duodenum of <em>Escherichia coli</em> F18-Sensitive and -Resistant Weaned Piglets by Lan Ye (140528)

“…Combining information on differential miRNA expression and their regulatory relationships with transcription factors, identified 12 candidate miRNA disease markers, including 11 miRNAs with increased expression, ssc-miR-143, ssc-let-7f, ssc-miR-30e, ssc-miR-148a, ssc-miR-148b, ssc-miR-181a, ssc-miR-192, ssc-miR-27b, ssc-miR-15b, ssc-miR-21, and ssc-miR-215, and one with decreased expression, ssc-miR-152. Quantitative real-time PCR analysis of candidate miRNA expression in a larger cohort of <em>E coli</em> F18-sensitive and -resistant animals confirmed the high-throughput sequencing results.…”

An integrated digital healthcare platform for diabetes management with AI-based dietary management: 48-week results from a randomized controlled trial by You-Bin Lee (3391988)

“…</p> <p><strong>RESULTS</strong> </p> <p>A total of 294 participants were randomly assigned to group A (n=99), B (n=97), or C (n=98). The decreases in HbA1c from baseline to 24 and 48 weeks in group B (-0.32±0.58% to 24 weeks, -0.28±0.56% to 48 weeks) and group C (-0.49±0.57% to 24 weeks, -0.44±0.62% to 48 weeks) were significantly larger than those in group A (-0.06±0.61% to 24 weeks, 0.07±0.78% to 48 weeks). …”

Detailed analysis of the importance of K432E mutation in NA on receptor binding and activity of recombinant proteins. by Wenjuan Du (393238)

“…In the absence of OC, the difference in hemagglutination was even larger (S1A Fig), presumably because the receptor density on the red blood cells is decreased by NA activity and a much higher receptor density is need for hemagglutination with N1432E than with N1 (B) Analysis of NA enzymatic activity by BLI kinetic assay was performed similarly as described previously [<a href="http://www.plospathogens.org/article/info:doi/10.1371/journal.ppat.1008816#ppat.1008816.ref020" target="_blank">20</a>]. …”

Profile of Immune Cells in Axillary Lymph Nodes Predicts Disease-Free Survival in Breast Cancer by Holbrook E Kohrt (275250)

“…Moreover, axillary node CD4 T cell and CD1a dendritic cell populations allowed more significant stratification of disease-free survival of patients with T1 (primary tumor size 2 cm or less) and T2 (5 cm or larger) tumors than all other patient characteristics. …”

Table2_Observational and genetic evidence support a relationship between cardiac autonomic function and blood pressure.xlsx by Zekai Chen (12253898)

“…In contrast, one ln(ms) unit increase of the root mean square of the successive differences (RMSSD) and corrected RMSSD (RMSSDc), decreased DBP by 1.79 and 1.83 mmHg, respectively. …”

Associations of Suboptimal Growth with All-Cause and Cause-Specific Mortality in Children under Five Years: A Pooled Analysis of Ten Prospective Studies by Ibironke Olofin (416327)

“…The strength of association increased monotonically as Z scores decreased. Pooled mortality HR was 1.52 (95% Confidence Interval 1.28, 1.81) for mild underweight; 2.63 (2.20, 3.14) for moderate underweight; and 9.40 (8.02, 11.03) for severe underweight. …”

Large-scale molecular dynamics simulations of different lipid membrane systems. by Kirsi H. Pietiläinen (43149)

“…(B) Average area per lipid of the eight simulated bilayer systems, indicating the packing or fluidity of the bilayer (smaller area means decreased fluidity). (C) The molecular order parameter (<i>S</i>_mol) profiles along selected unsaturated acyl chains. …”

Spatial, temporal, and demographic patterns in prevalence of chewing tobacco use in 204 countries and territories, 1990-2019: A systematic analysis from the Global Burden of Diseas... by Kendrick, Parkes J

“…Although global age-standardised prevalence of smoking tobacco use decreased significantly between 1990 and 2019 (annualised rate of change: –1·21% [–1·26 to –1·16]), similar progress was not observed for chewing tobacco (0·46% [0·13 to 0·79]). …”
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Image_2_Clinical significance of right ventricular–pulmonary arterial coupling in patients with tricuspid regurgitation before closure of atrial septal defect.TIF by Seon Hwa Lee (1687621)

“…On multivariable regression, persistent TR was independently associated with age [odds ratio (OR) 1.07, 95% confidence interval (CI) 1.01–1.14, p = 0.030) and |RV GLS|/PASP (OR 0.001, 95% CI 0.00–0.017, p = 0.012). …”

Acetylated HIF-2α regulates <i>in vitro</i> tumor cell properties. by Rui Chen (95310)

“…Comparison of samples within a given condition on the day of interest was performed by two-way (cell proliferation) or one-way (colony formation, cell migration, cell invasion) ANOVA followed by Dunnett’s multiple comparisons test using control shRNA knockdown/control rescue as reference with decreased samples noted (*, P<0.05). For proliferation data, the indicated samples (*) differ from control cells for at least five of the last six days in this seven-day protocol. …”

Examples of NF-68 expression (arrows in B-G) in the MGN (B-D) and MoDG of the hippocampus (E-G) from the NC (B and E), 21D-B (C and F) and 21D-B/T (D and G) cohorts. by Xiaoping Du (284656)

“…Error bars represent standard error of the means. Scale bar = 50 µm in G for B-G, = 500 µm in A.…”

Kidneys from Kif5b-Pax2KD (<i>Kif5bfl/-</i>:<i>Pax2-Cre</i>) embryos have a reduced cell proliferation rate. by Ju Cui (726069)

“…Bars represent the means ± S.D. Six sections from three wild type and three mutant embryos were imaged and counted. …”