Table3_Exploring the causal relationship: bidirectional mendelian randomization study on benign prostatic hyperplasia and cardiovascular diseases.XLSX by Nanyan Xiang (18124306)

“…</p>Results<p>Using a bidirectional two-sample MR study, we found that BPH patients had an increased risk of developing CHD (ConMix OR = 1.152, 95% CI: 1.011–1.235, p = 0.035) and MI (ConMix OR = 1.107.95% CI: 1.022–1.164, p = 0.013), but a decreased risk of stroke (ConMix OR = 0.872, 95% CI: 0.797–0.926, p = 0.002). …”

Table4_Exploring the causal relationship: bidirectional mendelian randomization study on benign prostatic hyperplasia and cardiovascular diseases.XLSX by Nanyan Xiang (18124306)

“…</p>Results<p>Using a bidirectional two-sample MR study, we found that BPH patients had an increased risk of developing CHD (ConMix OR = 1.152, 95% CI: 1.011–1.235, p = 0.035) and MI (ConMix OR = 1.107.95% CI: 1.022–1.164, p = 0.013), but a decreased risk of stroke (ConMix OR = 0.872, 95% CI: 0.797–0.926, p = 0.002). …”

Analysis of Differential miRNA Expression in the Duodenum of <em>Escherichia coli</em> F18-Sensitive and -Resistant Weaned Piglets by Lan Ye (140528)

“…Combining information on differential miRNA expression and their regulatory relationships with transcription factors, identified 12 candidate miRNA disease markers, including 11 miRNAs with increased expression, ssc-miR-143, ssc-let-7f, ssc-miR-30e, ssc-miR-148a, ssc-miR-148b, ssc-miR-181a, ssc-miR-192, ssc-miR-27b, ssc-miR-15b, ssc-miR-21, and ssc-miR-215, and one with decreased expression, ssc-miR-152. Quantitative real-time PCR analysis of candidate miRNA expression in a larger cohort of <em>E coli</em> F18-sensitive and -resistant animals confirmed the high-throughput sequencing results.…”

An integrated digital healthcare platform for diabetes management with AI-based dietary management: 48-week results from a randomized controlled trial by You-Bin Lee (3391988)

“…</p> <p><strong>RESULTS</strong> </p> <p>A total of 294 participants were randomly assigned to group A (n=99), B (n=97), or C (n=98). The decreases in HbA1c from baseline to 24 and 48 weeks in group B (-0.32±0.58% to 24 weeks, -0.28±0.56% to 48 weeks) and group C (-0.49±0.57% to 24 weeks, -0.44±0.62% to 48 weeks) were significantly larger than those in group A (-0.06±0.61% to 24 weeks, 0.07±0.78% to 48 weeks). …”

Detailed analysis of the importance of K432E mutation in NA on receptor binding and activity of recombinant proteins. by Wenjuan Du (393238)

“…In the absence of OC, the difference in hemagglutination was even larger (S1A Fig), presumably because the receptor density on the red blood cells is decreased by NA activity and a much higher receptor density is need for hemagglutination with N1432E than with N1 (B) Analysis of NA enzymatic activity by BLI kinetic assay was performed similarly as described previously [<a href="http://www.plospathogens.org/article/info:doi/10.1371/journal.ppat.1008816#ppat.1008816.ref020" target="_blank">20</a>]. …”

Profile of Immune Cells in Axillary Lymph Nodes Predicts Disease-Free Survival in Breast Cancer by Holbrook E Kohrt (275250)

“…Moreover, axillary node CD4 T cell and CD1a dendritic cell populations allowed more significant stratification of disease-free survival of patients with T1 (primary tumor size 2 cm or less) and T2 (5 cm or larger) tumors than all other patient characteristics. …”

Table2_Observational and genetic evidence support a relationship between cardiac autonomic function and blood pressure.xlsx by Zekai Chen (12253898)

“…In contrast, one ln(ms) unit increase of the root mean square of the successive differences (RMSSD) and corrected RMSSD (RMSSDc), decreased DBP by 1.79 and 1.83 mmHg, respectively. …”

Associations of Suboptimal Growth with All-Cause and Cause-Specific Mortality in Children under Five Years: A Pooled Analysis of Ten Prospective Studies by Ibironke Olofin (416327)

“…The strength of association increased monotonically as Z scores decreased. Pooled mortality HR was 1.52 (95% Confidence Interval 1.28, 1.81) for mild underweight; 2.63 (2.20, 3.14) for moderate underweight; and 9.40 (8.02, 11.03) for severe underweight. …”

Image_2_Clinical significance of right ventricular–pulmonary arterial coupling in patients with tricuspid regurgitation before closure of atrial septal defect.TIF by Seon Hwa Lee (1687621)

“…On multivariable regression, persistent TR was independently associated with age [odds ratio (OR) 1.07, 95% confidence interval (CI) 1.01–1.14, p = 0.030) and |RV GLS|/PASP (OR 0.001, 95% CI 0.00–0.017, p = 0.012). …”

The Effect of Complete Integration of HIV and TB Services on Time to Initiation of Antiretroviral Therapy: A Before-After Study by Bernhard Kerschberger (129359)

“…In adjusted analyses, patients attending the clinic post-integration were 1.60 times (95% CI 1.11–2.29) more likely to have started ART relative to the pre-integration period. …”

Computational Determination of Potential Inhibitors of SARS-CoV‑2 Main Protease by Son Tung Ngo (425258)

“…FEP results indicate that two natural compounds, cannabisin A and isoacteoside, and an HIV-1 PR inhibitor, darunavir, exhibit a large binding free energy to SARS-CoV-2 Mpro, which is larger than that of <b>13b</b>, the most reliable SARS-CoV-2 Mpro inhibitor recently reported. …”

Interim Effects of Zoledronate, Denosumab, or Teriparatide on Bone Microarchitecture in Type 2 Diabetes: A Pilot Trial by Trupti Nagendra Prasad (17266455)

“…</p><p dir="ltr">Interventions: Participants were randomized in 1:1:1:1 ratio to receive zoledronate 5 mg annually, denosumab 60 mg every 6 months, teriparatide 20 µg daily, or only standard of care (calcium/cholecalciferol) for 72 weeks. …”

Interim Effects of Zoledronate, Denosumab, or Teriparatide on Bone Microarchitecture in Type 2 Diabetes: A Pilot Trial by Trupti Nagendra Prasad (17266455)

“…</p><p dir="ltr">Interventions: Participants were randomized in 1:1:1:1 ratio to receive zoledronate 5 mg annually, denosumab 60 mg every 6 months, teriparatide 20 µg daily, or only standard of care (calcium/cholecalciferol) for 72 weeks. …”

Supplementary Material for: Impacts of air pollution on dynamic lung function in asthma patients: the modifying effect of phenotype susceptibility and possible relationship with ai... by figshare admin karger (2628495)

“…Results We found that a 10 μg/m3 increase in PM2.5 was associated with decreases 0.79% in FEF25-75 (95% CI: 0.31 ~ 3.25), a range of decreases of 0.76%~0.83% PEF, 1.58%~1.93% for FEF25 and 1.79%~2.31% for FEF50 in the morning or evening on different lag days. …”

Metabolic features of Gulf War illness by Robert K. Naviaux (256148)

“…</p><p>Methods</p><p>Targeted, broad-spectrum serum metabolomics was used to gain insights into the biology of GWI. 40 male participants, included 20 veterans who met both Kansas and CDC diagnostic criteria for GWI and 20 nonveteran controls without similar symptoms that were 1:1 matched to GWI cases by age, sex, and ethnicity. …”

Ligand Stereoelectronic Effects in Complexes of Phospholanes, Phosphinanes, and Phosphepanes and Their Implications for Hydroformylation Catalysis by R. Angharad Baber (2508466)

“…Convenient syntheses are described for the five-, six-, and seven-membered phosphacycles PhP(CH₂)<i>_x</i>_-1, where <i>x</i> = 5 (<b>L</b><b>^a</b><b>₅</b>), 6 (<b>L</b><b>^a</b><b>₆</b>), 7 (<b>L</b><b>^a</b><b>₇</b>), and Bu^tP(CH₂)<i>_x</i>_-1 where <i>x</i> = 5 (<b>L</b><b>^b</b><b>₅</b>), 6 (<b>L</b><b>^b</b><b>₆</b>), 7 (<b>L</b><b>^b</b><b>₇</b>). …”

Table_2_Pan-Soft Tissue Sarcoma Analysis of the Incidence, Survival, and Metastasis: A Population-Based Study Focusing on Distant Metastasis and Lymph Node Metastasis.docx by Haotian Liu (5512757)

“…Patients with only lymph node metastases (N1/2M0) had a significantly worse prognosis than those without metastases (N0M0) but a better prognosis than those with only distant metastases (N0M1) (p<0.0001). …”

Table_7_Pan-Soft Tissue Sarcoma Analysis of the Incidence, Survival, and Metastasis: A Population-Based Study Focusing on Distant Metastasis and Lymph Node Metastasis.docx by Haotian Liu (5512757)

“…Patients with only lymph node metastases (N1/2M0) had a significantly worse prognosis than those without metastases (N0M0) but a better prognosis than those with only distant metastases (N0M1) (p<0.0001). …”

Table_5_Pan-Soft Tissue Sarcoma Analysis of the Incidence, Survival, and Metastasis: A Population-Based Study Focusing on Distant Metastasis and Lymph Node Metastasis.docx by Haotian Liu (5512757)

“…Patients with only lymph node metastases (N1/2M0) had a significantly worse prognosis than those without metastases (N0M0) but a better prognosis than those with only distant metastases (N0M1) (p<0.0001). …”

Reduced Graphene Oxide Paper Electrode: Opposing Effect of Thermal Annealing on Li and Na Cyclability by Lamuel David (1677751)

“…Maximum sodium charge capacity of ∼140 mAh·g^–1_anode at 100 mA·g^–1_anode (∼98 mAh·cm_anode^–3 at ∼70 μA·cm^–2) was realized for specimen reduced at 500 °C. …”