Evolution of New <i>cis</i>-Regulatory Motifs Required for Cell-Specific Gene Expression in <i>Caenorhabditis</i> by Michalis Barkoulas (3097899)

“…In this induction event, a single cell, the gonadal anchor cell, secretes LIN-3/EGF and induces three out of six competent precursor cells to acquire a vulval fate. …”

Minimum Initial Application and Price Discrimination in the Fund Market by Rafael de Braga Castilho (8370129)

“…<div><p>Abstract Banks offer multiple funds that vary in its characteristics. Usually funds with larger minimum initial application have lower administration fees, which could be due to lower costs. …”

Isolated hypothalamic neurons from E19 embryos. by Kinning Poon (469702)

“…Results are expressed as means ± SEM (n = 4). *<i>p</i> < 0.05, compared with chow. ENK = enkephalin; scale bar is 25 µM. …”

Figure 5 by David Heister (426551)

“…<p>A: <i>r</i> values for all regions across conditions show a larger inverse correlation and a decrease in positive correlation in the zECO conditions. …”

FRET Sensor calibration in the nucleus. by Jose G. Miranda (118268)

“…A) NLS-ZapSM2 FRET ratio increases slightly above resting suggesting that it is close to saturation at rest; B) NLS-ZapSR2, FRET ratio goes above resting; C) NLS-ZapOC2 has a small decrease in FRET ratio after TPEN and a larger increase after treatment with Zn²⁺; D) NLS-ZapOK2 exhibits a small change in FRET ratio after TPEN and Zn²⁺; E) NLS-ZapCmR1 has an inverted response in which TPEN causes an increase in FRET ratio while Zn²⁺ with digitonin causes a decrease in the ratio; F) NLS-ZapCmR1.1 displays a decrease in the FRET ratio after TPEN and large increase with Zn²⁺ and digitonin; G) NLS-ZapCmR2 is similar to ZapCmR1.1. …”

FRET Sensor calibration in the cytosol. by Jose G. Miranda (118268)

“…A) NES-ZapSM2, FRET ratio goes slightly above resting; B) NES-ZapSR2 has a similar response as observed in the nucleus, <a href="http://www.plosone.org/article/info:doi/10.1371/journal.pone.0049371#pone-0049371-g002" target="_blank">Figure 2B</a>; C) NES-ZapOC2 demonstrates a small decrease after TPEN compared to the same sensor in the nucleus; D) NES-ZapOK2 is observed with small changes in FRET ratio after TPEN and Zn²⁺/digitonin; E) NES-ZapCmR1 has an inverted response in which TPEN causes an increase in FRET ratio while Zn²⁺ with digitonin causes a decrease in the ratio; F) NES-ZapCmR1.1 and G) NES-ZapCmR2 exhibit a small decrease with TPEN and a larger increase in FRET ratio after addition of Zn²⁺ and digitonin. …”

Sequence gaps exclusive to both Archaea and Microsporidia 16S rRNAs. by Chaitanya Muralidhara (223748)

“…(<i>a</i>) The 100 gaps conserved in both the Archaea and Microsporidia map to the entire substructures I–III in the secondary structure model of the bacterium <i>E. coli</i> <a href="http://www.plosone.org/article/info:doi/10.1371/journal.pone.0018768#pone.0018768-Cannone1" target="_blank">[14]</a>. …”

Calcium levels in PC12 cells exposed to SMF, the A_2AR agonist CGS21680 or antagonist ZM241385. by Zhiyun Wang (360002)

“…Cells treated with 1.0 µM CGS21680 experienced decreased Ca²⁺ release compared to control cells while co-treatment of the cells with this agonist and either 1.0 µM ZM241385 or SMF attenuated the CGS21680-induced decrease (<i>p</i> values for each comparison are shown on the chart for n = 3 independent experiments).…”

RNA Microarray Analysis in Prenatal Mouse Cochlea Reveals Novel IGF-I Target Genes: Implication of MEF2 and FOXM1 Transcription Factors by Hortensia Sanchez-Calderon (186893)

“…By contrast, there was an increase in the nuclear accumulation of FoxM1 and a corresponding decrease in the nuclear cyclin-dependent kinase inhibitor p27^Kip1.…”

Comprehensive Analysis of the Naturally Processed Peptide Repertoire: Differences between HLA-A and B in the Immunopeptidome by Ingrid M. M. Schellens (377152)

“…<div><p>The cytotoxic T cell (CTL) response is determined by the peptide repertoire presented by the HLA class I molecules of an individual. We performed an in-depth analysis of the peptide repertoire presented by a broad panel of common HLA class I molecules on four B lymphoblastoid cell-lines (BLCL). …”

Properties of evolved FUS PLD. by Simon M. Lichtinger (11326846)

“…In genetic-algorithm runs which increase <i>T</i>_c, hydrophobic amino acids become favoured, whilst the converse holds for genetic-algorithm runs which decrease <i>T</i>_c. …”

Image_1_Effect of Flaxseed Supplementation in Diet of Dairy Cow on the Volatile Organic Compounds of Raw Milk by HS-GC–IMS.pdf by Guoxin Huang (5775458)

“…A total of 40 VOCs including three acids, six esters, 11 aldehydes, seven alcohols, 13 ketones were identified in all the raw milk samples. …”

<i>In Vivo</i> Changes in Lamina Cribrosa Microarchitecture and Optic Nerve Head Structure in Early Experimental Glaucoma by Kevin M. Ivers (778159)

“…In EG monkeys, an increase in mean ALCS Depth (ALCSD) was the first structural change measured in 6 of 7 EG eyes. A decrease in mean minimum rim width (MRW) simultaneously accompanied this early change in 4 of 6 EG eyes and was the first structural change in the 7^th EG eye. …”

Changes in Network and Node Properties Associated with Increasing Vulnerability. by Christine Moore (517762)

“…(b) Number of components (number of independent/isolated sub groups) – A decrease in the number of isolated groups increases the reachability of any random node (c) Giant Component (largest independent/isolated sub group) – if the largest component contracts infection, this infection can spread further through the Giant Component compared to smaller, more isolated components which will make the whole network more vulnerable. …”

Subsample analysis of supply-side explanations. by Santiago Carbo-Valverde (9575368)

“…<p>Fig 18 reports the relative importance—measured by mean decrease in accuracy—of those variables with the largest predictive power for the adoption of online banking by banks’ characteristics: size (large banks’ customers—Santander, BBVA, and CaixaBank—vs other banks’ customers) and branch closure (customers whose main bank closed at least one branch in their province vs customers whose main bank has not closed any branch in their province). …”

Increased Response to Glutamate in Small Diameter Dorsal Root Ganglion Neurons after Sciatic Nerve Injury by Kerui Gong (429477)

“…We recorded neuronal responses from the <i>ex-vivo</i> preparations of the dorsal root ganglia (DRG) one week following a chronic constriction injury (CCI) of the sciatic nerve in adult rats. …”

Fig 4 - by Samuel Thomas (6001970)

“…Volcano plots show 3079 and 2658 total <i>m/z</i> features, respectively; enlarged dots indicate significantly modulated features (Student’s <i>t</i>-test <i>p</i>-value < 0.05 and fold-change ≥ 50%); red indicates increase with JC virus, green indicates decrease with JC virus. …”

MyD88 influences the response of hematopoietic cells after stroke. by Catherine E. Downes (385077)

“…When the infarct volume is calculated from the TTC stained tissue the WT + <i>Myd88^−/−</i> groups shows a larger infarct volume than the WT + WT groups, whilst there is no difference between the <i>MyD88^−/−</i> + WT and the WT + WT infarct volume (n = 9). …”

Testing Dose-Dependent Effects of the Nectar Alkaloid Anabasine on Trypanosome Parasite Loads in Adult Bumble Bees by Winston E. Anthony (823308)

“…To determine how secondary compound consumption affects survival and pathogen load in <i>Bombus impatiens</i>, we manipulated the presence of a common gut parasite, <i>Crithidia bombi</i>, and dietary concentration of anabasine, a nectar alkaloid produced by <i>Nicotiana</i> spp. using four concentrations naturally observed in floral nectar. …”

Supplementary Material for: Assessment of the Corticospinal Tract Profile in Pure Lower Motor Neuron Disease: A Diffusion Tensor Imaging Study by Sarica A. (7851320)

“…Moreover, a random forest (RF) classifier was trained to evaluate the ability of CST diffusion metrics in distinguishing pairwise the groups from the controls. <b><i>Results:</i></b> ALS patients presented wide microstructural abnormalities in the entire CST as assessed by FA decrease and RD increase while pLMND patients showed focal FA decrease and a larger AD increase in the cerebral peduncle and posterior limb of the internal capsule in comparison with controls. …”