Homolog pairing and sister chromatid cohesion in interphase remain unaffected genome-wide after knockdown of Rad21. by T. Niroshini Senaratne (3067776)

“…(C) Schematic showing the three major chromosomes of Drosophila and summarizing the effects of Rad21 knockdown, with heterochromatic FISH targets highlighted in grey, smaller euchromatic FISH targets (tens to hundreds of kilobases) highlighted in yellow, and larger euchromatic FISH targets (several megabases) highlighted in pink. …”

The Effect of Automated Alerts on Provider Ordering Behavior in an Outpatient Setting by Andrew W Steele (275257)

“…<div><h3>Background</h3><p>Computerized order entry systems have the potential to prevent medication errors and decrease adverse drug events with the use of clinical-decision support systems presenting alerts to providers. …”

DataSheet1_Design and evaluation of a ball spline wasp-inspired needle.xlsx by Jette Bloemberg (11665612)

“…Furthermore, evaluation in 15-wt%, 10-wt%, and 5-wt% gelatin tissue phantoms showed that decreasing the gelatin concentration decreased the mean slip ratios from 0.35 to 0.19 and 0.18, respectively. …”

Video 2; Footage of several trials in the experiment from the participant's point of view (.avi) from The confusion effect when attacking simulated three-dimensional starling flock... by Benedict G. Hogan (3604364)

“…The confusion effect describes the phenomenon of decreasing predator attack success with increasing prey group size. …”

Osseointegration of an innovative functionally gradient biomimetic scaffold based on Voronoi-Tessellation for the design of orthopaedic implants by Yuzhu Wang (845659)

“…Animal experiments suggested that groups with larger pore sizes exhibited superior performance in promoting bone growth <i>in vivo</i> based on BV/TV and Tb.N measurement.…”

Reduction in denervation-induced atrophy of muscle fibers after combination treatment with erythropoietin and dexamethasone. by Jung Il Lee (4358167)

“…(n = 3 / group; **<i>P</i> < 0.05 vs. saline-treated group; saline, mice treated with saline; EPO, mice treated with erythropoietin; Dexa, mice treated with dexamethasone; EPO+Dexa, mice treated with erythropoietin and dexamethasone).…”

Data File; Text file containing all participant data from The confusion effect when attacking simulated three-dimensional starling flocks by Benedict G. Hogan (3604364)

“…The confusion effect describes the phenomenon of decreasing predator attack success with increasing prey group size. …”

Substitution outcomes do not correlate with amino acid frequency. by Sarah Meinhardt (503481)

“…No change corresponds to a value of 1 (dashed black line). The straight dotted lines indicate 2-fold change from the starting protein; this range is usually larger than the error bars of a repression measurement. …”

DataSheet2_A thermodynamically consistent monte carlo cross-bridge model with a trapping mechanism reveals the role of stretch activation in heart pumping.ZIP by Kazunori Yoneda (11271150)

“…Based on our numerical analysis, we draw the following conclusions regarding the stretch activation mechanism: (i) the delayed force becomes larger than the original isometric force because the population of trapped myosin molecules and their average force increase after stretching; (ii) the delayed force has a duration of more than a few seconds owing to a fairly small rate constant of escape from the trapped state. …”

The impact of a breast cancer diagnosis on health-related quality of life. A prospective comparison among middle-aged to elderly women with and without breast cancer by Randi V. Karlsen (2545756)

“…</p> <p><b>Results</b> Women with breast cancer reported significantly larger decreases in HQoL from before to after diagnosis than those who remained breast cancer-free (physical component summary, −2.0; 95% CI −2.8; −1.2, mental component summary, −1.5, 95% CI −2.3; −0.6). …”

Video2_A thermodynamically consistent monte carlo cross-bridge model with a trapping mechanism reveals the role of stretch activation in heart pumping.MP4 by Kazunori Yoneda (11271150)

“…Based on our numerical analysis, we draw the following conclusions regarding the stretch activation mechanism: (i) the delayed force becomes larger than the original isometric force because the population of trapped myosin molecules and their average force increase after stretching; (ii) the delayed force has a duration of more than a few seconds owing to a fairly small rate constant of escape from the trapped state. …”

Supplementary Material for: A Systematic Review on the Impact of Genetic Testing for Familial Melanoma II: Psychosocial Outcomes and Attitudes by Primiero C.A. (10045595)

“…<b><i>Background:</i></b> Although genetic testing for known familial melanoma genes is commercially available, clinical implementation has been restrained as utility is unclear, concerns of causing psychological distress are often cited, and consumer interest and perceptions are not well understood. …”

Supplementary Material for: Intra-Amniotic Sildenafil Treatment Promotes Lung Growth and Attenuates Vascular Remodeling in an Experimental Model of Congenital Diaphragmatic Hernia by Okolo F. (9118589)

“…The effect of prenatal intra-amniotic treatment with sildenafil on survival, lung growth, and vascular morphology in the nitrofen model was determined. <b><i>Results:</i></b> Nitrofen-treated embryos exhibited decreased blood flow in the lung periphery compared to controls, and intra-amniotic sildenafil significantly improved embryonic pulmonary blood flow. …”

Data_Sheet_1_A Prospective Multicenter Trial to Evaluate Urinary Metabolomics for Non-invasive Detection of Renal Allograft Rejection (PARASOL): Study Protocol and Patient Recruitm... by Miriam C. Banas (2827475)

“…To further validate our results in a large real-world patient cohort, we designed a multicentric observational prospective study (PARASOL) including six independent European transplant centers. …”

DataSheet_1_Evidence on Efficacy and Safety of Chinese Medicines Combined Western Medicines Treatment for Breast Cancer With Endocrine Therapy.docx by Lu Li (14069)

“…There were no limitations on the languages. We extracted data from the included RCTs, assessed study quality, conducted meta-analyses by RevMan 5.4 and compared the pooled Risk Ratios (RR) or Mean Difference (MD) with 95% CIs.…”

DataSheet_1_Kinetics of vaccine-induced neutralizing antibody titers and estimated protective immunity against wild-type SARS-CoV-2 and the Delta variant: A prospective nationwide... by Eliel Nham (13847299)

“…Estimations of vaccine-induced protective immunity against VOCs are essential for setting proper COVID-19 vaccination policy.</p>Methods<p>We performed plaque-reduction neutralizing tests (PRNTs) using sera from healthcare workers (HCWs) collected from baseline to six months after COVID-19 vaccination and from convalescent COVID-19 patients. …”

High-Resolution Diffusion Tensor Spinal Cord MRI Measures as Biomarkers of Disability Progression in a Rodent Model of Progressive Multiple Sclerosis by Francesca Gilli (253853)

“…Lower disability scores were associated with decreased fractional anisotropy values measured in the ventral (r = 0.68; <i>p</i><0.0001) and ventral-lateral (r = 0.70; <i>p</i><0.0001) regions of the white matter. …”

Predicted performance of a control program administered to dogs on arrival in US animal shelters. by Benjamin D. Dalziel (650353)

“…White lines show medians and shaded areas enclose the 5^th to the 95^th percentiles of the simulation data. (<b>B</b>) Decreasing control efficacy to 75% can still achieve eradication in isolated shelters (blue region, solid line), however shelters that transfer dogs amongst themselves at the observed mean rate of τ = 0.1 would preserve CIV in a few shelters despite the vaccination program (red region, dashed line). …”

Pharmacogenetic effect on the sensitivity parameter. by Christoph Eisenegger (430948)

“…<p>Administration of L-DOPA increases the sensitivity for making transfers that subjectively provide the largest expected return in player As who carry the 10/10R DAT1 genotype (lower endogenous striatal dopamine levels) (placebo: n = 22; L-DOPA: n = 28), but decreases this sensitivity in those who carry the 9/10R DAT1 genotype (higher endogenous striatal dopamine levels) (placebo: n = 27; L-DOPA: n = 16). …”

Analysis of the long-term effects of groundwater extraction on the water balance in part of the Urucuia Aquifer System in Bahia - Brazil by Leanize Teixeira Oliveira (8073563)

“…After defining well production rates from field surveys (4.6 m3 s-1) and modeling of the aquifer base geometry (maximum thickness of 535 m), the steady-state models with and without pumping show that, in the long term, groundwater storage decreases by 2 km3 (0.8 m on average in the aquifer) without interference in the regional flow direction. …”