Image2_Multi-omics analysis reveals the prognostic and tumor micro-environmental value of lumican in multiple cancer types.TIF by Zehuai Guo (16875003)

“…Among them, LUM expression displayed a significant positive correlation with CAFs and their factors, and exhibited immunosuppressive effects in six independent immunotherapy cohorts.</p><p>Conclusion: Multi-omics analysis suggests that LUM may have been a prognostic marker, contributed to immunosuppression in the TME, and decreased the effectiveness of immune checkpoint inhibitors.…”

Table1_Multi-omics analysis reveals the prognostic and tumor micro-environmental value of lumican in multiple cancer types.XLSX by Zehuai Guo (16875003)

“…Among them, LUM expression displayed a significant positive correlation with CAFs and their factors, and exhibited immunosuppressive effects in six independent immunotherapy cohorts.</p><p>Conclusion: Multi-omics analysis suggests that LUM may have been a prognostic marker, contributed to immunosuppression in the TME, and decreased the effectiveness of immune checkpoint inhibitors.…”

Validation and predictive accuracy of the cerebrovascular model, by Hadi Esfandi (21387211)

“…This suggests that superficial PAs are prone to larger distortions in their lumen diameters, since their MT mechanism must perform over a wider range of WT, (f) mean and standard deviation of blood flow resistance per 10 micrometer length of PA1. …”

Table_1_Proteomic Analysis of the Protective Effect of Eriodictyol on Benzo(a)pyrene-Induced Caco-2 Cytotoxicity.XLSX by Chong Wang (120449)

“…<p>We evaluated the possible protective effects of six polyphenols on benzo(a)pyrene (BaP)-induced cytotoxicity in Caco-2 cells. …”

Flow amplitude in untreated vessels, arterioarterial (AA) and arteriovenous (AV) loops. by Volker J. Schmidt (313862)

“…All values are mean+/-SEM, number of observations (n) is identical to <a href="http://www.plosone.org/article/info:doi/10.1371/journal.pone.0117407#pone.0117407.g003" target="_blank">Fig. 3</a>. #: <i>P</i><0.05.</p>…”

Catastrophic dynamics of the population shown in Fig 5. by Albertas Janulevicius (732672)

“…(C) A close-up of a catastrophe: (i) population size, (ii) glucose dynamics and (iii) FBP dynamics of two example cells, strongly imbalanced (<i>B</i>_g,1 = 0.15 mM, light orange) and weakly imbalanced (<i>B</i>_g,1 = 0.55 mM, dark orange). …”

Estimation of a Floquet multiplier (FM) using linear regression. by Jooeun Ahn (299192)

“…<p>Time series with different length, <i>n</i> were generated using <a href="http://www.plosone.org/article/info:doi/10.1371/journal.pone.0119596#pone.0119596.e003" target="_blank">Equation (1)</a>. …”

ERG responses before and after LD. by Delu Song (464991)

“…<p>Before LD, rod-a (<i>P</i><0.05) and rod-b (<i>P</i><0.05) waves were decreased in CD59aKO Balb/c mice compared to WT (A). …”

The depth of coverage over the reference sequences (87.5 Mbps) by cultivars, and across all cultivars. by Elhan S. Ersoz (132711)

“…<p>The fraction of the reference covered in each cultivar's individual sequence library was largest at 1x, and was decreasing in size as the coverage increased. …”

Table 2_Longitudinal immune profiling following autologous hematopoietic stem cell transplantation in multiple sclerosis: insights into immune reconstitution and disease modulation... by Malin Müller (3308340)

“…CD4 T-cell reconstitution demonstrated a shift from central memory (T_cm) to effector memory (T_em) phenotypes, with a selective depletion of polyfunctional Th1/Th17cells lacking PD-1 expression. Clusters enriched for PD-1⁺ T_em CD4 T cells appeared to differ between patients with and without EIDA. …”

Data Sheet 2_Longitudinal immune profiling following autologous hematopoietic stem cell transplantation in multiple sclerosis: insights into immune reconstitution and disease modul... by Malin Müller (3308340)

“…CD4 T-cell reconstitution demonstrated a shift from central memory (T_cm) to effector memory (T_em) phenotypes, with a selective depletion of polyfunctional Th1/Th17cells lacking PD-1 expression. Clusters enriched for PD-1⁺ T_em CD4 T cells appeared to differ between patients with and without EIDA. …”

Using a DAP to fit an increasing IoD range. by Duncan J. MacGregor (302359)

“…The presence of a large AHP results in a decreasing IoD range, where variability is less at larger binwidths [<a href="http://www.ploscompbiol.org/article/info:doi/10.1371/journal.pcbi.1007092#pcbi.1007092.ref021" target="_blank">21</a>]. …”

<b>Complement inhibition reshapes tumor microenvironment and enhances clinical efficacy in immunotherapy</b> by Xi Jiao (10224854)

“…<p dir="ltr">We conducted single-cell transcriptome (scRNA-seq) and whole-exome sequencing (WES) analyses on 9 esophageal cancer patients, consisting of three cases with complement mutations and six cases without mutations, resulting in a total of 52,727 cells after quality control. …”

<b>Complement inhibition reshapes tumor microenvironment and enhances clinical efficacy in immunotherapy</b> by Xi Jiao (10224854)

“…<p dir="ltr">We conducted single-cell transcriptome (scRNA-seq) and whole-exome sequencing (WES) analyses on 10 esophageal cancer patients, consisting of four cases with complement mutations and six cases without mutations, resulting in a total of 52,727 cells after quality control. …”

EDA-DATA by QiMin Zhou (17299183)

“…<p dir="ltr">Nineteen ectodysplasin-A variants were identified, six of which were not previously reported. Among these variants, we identified a patient who carried two mutations in ectodysplasin-A and exhibited more severe phenotypes. …”

Responses of example rACC neurons: rasters and spike density plots. by Koji Toda (334817)

“…B, Increasing type I activity (largest response at the rewarded trial), aligning on the deactivation of reward apparatus in the last drop. …”

When resolution does matter: Modelling indirect contacts in dairy farms at different levels of detail - Fig 3 by Alba Bernini (7512641)

“…The lighter area represents the whiskers: the upper [lower] whisker extends from the hinge to the largest [smallest] value no further than 1.5 x IQR from the hinge, where IQR is the interquartile range. …”

Dissociation of the gamma rhythm and high-gamma activity by manipulating stimulus size. by Supratim Ray (224895)

“…The black line shows the LFP energy in the baseline period. (D–F) and (G–I) show corresponding population responses of 15 and 104 sites from Monkeys 1 and 2, respectively. …”

Location of the study area. by Zhuoya Zhang (5755061)

“…In 1996, the overall landscape ecological safety was good, with 63.5% of the total area of grade I and II. In 2003, the proportion of the grade I and grade II areas decreased, with landscape ecological security problems appearing. …”

Data_Sheet_1_Establishment of sheep nasal mucosa explant model and its application in antiviral research.docx by Jian Zheng (287758)

“…IFN decreased significantly after the PRV infection. Similarly, we used this NMEM model to screen several antiviral substances, such as probiotics and drugs. …”