Inotodiol decreases clone formation in HCC cells. by Yushuang Xing (20636685)

“…In addition, inotodiol showed to induce apoptosis, characterized by an increase in Bax expression, a decrease in Bcl-2, Bcl-XL and MCL1 expression, the initiation of cleaved PARP1 and cleaved caspase 3, and inhibition of the MAPK/ERK pathway. …”

Inotodiol decreases clone formation in HCC cells. by Yushuang Xing (20636685)

Decreased cytokine expression in J2.2-HKU1.7b-infected BMDM. by Chaminda D. Gunawardene (22794593)

Decreasing oxygen saturation with corresponding levels of NLR and D-dimer for understanding the interplay of inflammation. by Narendran Gopalan (110148)

Development of a CRISPR/Cas-Based Detection Platform for Tracking Decreased Susceptibility to Cephalosporins in Neisseria gonorrheae by Ziyuan Zhao (2889005)

“…We have developed the Multiplex Integrated RPA-CRISPR/Cas12a detection Assay (MIRCA) for simultaneous detection of Neisseria gonorrheae (<i>Ng</i>) and mutations with decreased susceptibility to cephalosporins. …”

IFN-γ and several PARP genes are upregulated in infected olfactory bulbs of JHMV infected mice. by Catherine M. Kerr (21492574)

stress-strain curves. by Junxia Zhou (14381598)

Cell cycle-specific expression of Clb1 and Clb2 protein was also decreased in the <i>puf5</i>Δ mutant. by Megumi Sato (4116994)

PARP9 knockdown promotes apoptosis and DNA damage. by Yating Li (1819822)

“…(E) DNA damage in GC cells significantly increased post-PARP9 knockdown as determined by comet assay. (F) The anti-DNA damage capacity of GC cells decreased markedly following reduction of PARP9 expression. …”

Bacterial strains and plasmids. by Eunsil Choi (8271039)

“…This functional attenuation was corroborated by the decrease in virulence observed in the 14028Δ<i>bipA</i> strain in a mouse model. …”

Strains used in this study. by Zachary T. Hying (21512605)

“…In strains lacking <i>efgA</i>, we showed that inflated intracellular formaldehyde pools were accompanied by decreased cell viability, while the loss of <i>ttmR</i> resulted in the loss of one-carbon metabolites to the extracellular space. …”

Strains and reagents used in this study. by Longjun Pu (20685717)

Stress-strain curves under different sizes. by Junxia Zhou (14381598)

Data Sheet 1_Imaging-based assessment of response to olaparib in platinum-sensitive relapsed ovarian cancer patients.pdf by Maria Delgado-Ortet (8840702)

“…In this work, we developed noninvasive imagingbased measurements of spatial and longitudinal heterogeneity in a retrospective analysis of a phase 2 non-randomized study of germline BRCA1/BRCA2 mutated (gBRCAm) ovarian cancer patients treated with combination of PARP inhibitors (PARPi) and immune checkpoint inhibitors (ICIs).…”

Net work vs phase of activation and lattice spacing. Top) We simulated work loops in the half sarcomere model at phases of activation of 0 to 0.95 in 0.05 increments, as well as ov... by Travis Carver Tune (21012349)

WT and ∆<i>lcrF</i> strains grew similarly in M9 media and exhibit similar gentamicin susceptibility. by Justin Greene (306625)

Data from: Spillage and food dust do not decrease efficacy of long-lasting insecticide-incorporated netting against stored product insects by Sabita Ranabhat (17484660)

PARP cleavage analysis of sgCtrl and <i>IRF1</i> KO cells across conditions with and without vaccinia virus infection. by Tyron Chang (9922533)

Conformational Role of Methyl in the Potency of Cyclohexane-Substituted Squaramide CCR6 Antagonists by Brian S. Gerstenberger (1936534)

“…CCR6 is a chemokine receptor that mediates the migration of pathogenic inflammatory leukocytes to sites of inflammation in response to its ligand, CCL20. Herein we report the design of a potent CCR6 antagonist capable of inhibiting the chemotactic migration of CCR6⁺ T cells in vitro. …”

Conformational Role of Methyl in the Potency of Cyclohexane-Substituted Squaramide CCR6 Antagonists by Brian S. Gerstenberger (1936534)

“…CCR6 is a chemokine receptor that mediates the migration of pathogenic inflammatory leukocytes to sites of inflammation in response to its ligand, CCL20. Herein we report the design of a potent CCR6 antagonist capable of inhibiting the chemotactic migration of CCR6⁺ T cells in vitro. …”