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marked decrease » marked increase (Expand Search)
based decrease » caused decreased (Expand Search), based defense (Expand Search)
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a large » _ large (Expand Search)
marked decrease » marked increase (Expand Search)
based decrease » caused decreased (Expand Search), based defense (Expand Search)
large decrease » larger decrease (Expand Search), large increases (Expand Search), large degree (Expand Search)
a large » _ large (Expand Search)
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Conformational Role of Methyl in the Potency of Cyclohexane-Substituted Squaramide CCR6 Antagonists
Published 2025“…Evidence generated through the characterization of conformationally restricted analogues supports the conclusion that the large potency enhancement is the result of the methyl substituent biasing the cyclohexane ring ground state conformation to favor that of the bound ligand and thus decreasing the ligand strain energy.…”
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Conformational Role of Methyl in the Potency of Cyclohexane-Substituted Squaramide CCR6 Antagonists
Published 2025“…Evidence generated through the characterization of conformationally restricted analogues supports the conclusion that the large potency enhancement is the result of the methyl substituent biasing the cyclohexane ring ground state conformation to favor that of the bound ligand and thus decreasing the ligand strain energy.…”
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Conformational Role of Methyl in the Potency of Cyclohexane-Substituted Squaramide CCR6 Antagonists
Published 2025“…Evidence generated through the characterization of conformationally restricted analogues supports the conclusion that the large potency enhancement is the result of the methyl substituent biasing the cyclohexane ring ground state conformation to favor that of the bound ligand and thus decreasing the ligand strain energy.…”
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Table 1_Effect of decreased suspended sediment content on chlorophyll-a in Dongting Lake, China.docx
Published 2025“…The reduction in SSC may influence chlorophyll-a (Chl-a) concentrations in water, thereby further affecting the aquatic ecological environment. …”
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