يعرض 1 - 20 نتائج من 2,692 نتيجة بحث عن '(( strains ((over decrease) OR (((we decrease) OR (sizes decrease)))) ) OR ( a large decrease ))', وقت الاستعلام: 0.79s تنقيح النتائج
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    Conformational Role of Methyl in the Potency of Cyclohexane-Substituted Squaramide CCR6 Antagonists حسب Brian S. Gerstenberger (1936534)

    منشور في 2025
    "…Evidence generated through the characterization of conformationally restricted analogues supports the conclusion that the large potency enhancement is the result of the methyl substituent biasing the cyclohexane ring ground state conformation to favor that of the bound ligand and thus decreasing the ligand strain energy.…"
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    Conformational Role of Methyl in the Potency of Cyclohexane-Substituted Squaramide CCR6 Antagonists حسب Brian S. Gerstenberger (1936534)

    منشور في 2025
    "…Evidence generated through the characterization of conformationally restricted analogues supports the conclusion that the large potency enhancement is the result of the methyl substituent biasing the cyclohexane ring ground state conformation to favor that of the bound ligand and thus decreasing the ligand strain energy.…"