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we decrease » _ decrease (Expand Search), a decrease (Expand Search), nn decrease (Expand Search)
strains we » strains _ (Expand Search), strains b (Expand Search), strains where (Expand Search)
marked decrease » marked increase (Expand Search)
large decrease » larger decrease (Expand Search), large increases (Expand Search), large degree (Expand Search)
we decrease » _ decrease (Expand Search), a decrease (Expand Search), nn decrease (Expand Search)
strains we » strains _ (Expand Search), strains b (Expand Search), strains where (Expand Search)
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Conformational Role of Methyl in the Potency of Cyclohexane-Substituted Squaramide CCR6 Antagonists
Published 2025“…Evidence generated through the characterization of conformationally restricted analogues supports the conclusion that the large potency enhancement is the result of the methyl substituent biasing the cyclohexane ring ground state conformation to favor that of the bound ligand and thus decreasing the ligand strain energy.…”
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Conformational Role of Methyl in the Potency of Cyclohexane-Substituted Squaramide CCR6 Antagonists
Published 2025“…Evidence generated through the characterization of conformationally restricted analogues supports the conclusion that the large potency enhancement is the result of the methyl substituent biasing the cyclohexane ring ground state conformation to favor that of the bound ligand and thus decreasing the ligand strain energy.…”
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Conformational Role of Methyl in the Potency of Cyclohexane-Substituted Squaramide CCR6 Antagonists
Published 2025“…Evidence generated through the characterization of conformationally restricted analogues supports the conclusion that the large potency enhancement is the result of the methyl substituent biasing the cyclohexane ring ground state conformation to favor that of the bound ligand and thus decreasing the ligand strain energy.…”
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Overview of the parameters used in the model.
Published 2024“…<div><p>Background</p><p>Chikungunya virus (CHIKV) outbreaks, driven by the expanding habitat of the <i>Aedes albopictus</i> mosquito and global climate change, pose a significant threat to public health. Our study evaluates the effectiveness of emergency vaccination using a dynamic disease transmission model for a potential large-scale outbreak in Rome, Italy.…”
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Mortality rates per lifecycle stage [28].
Published 2024“…<div><p>Background</p><p>Chikungunya virus (CHIKV) outbreaks, driven by the expanding habitat of the <i>Aedes albopictus</i> mosquito and global climate change, pose a significant threat to public health. Our study evaluates the effectiveness of emergency vaccination using a dynamic disease transmission model for a potential large-scale outbreak in Rome, Italy.…”