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Data Sheet 1_Bio-functional hydrogel coated membranes to decrease T-cell exhaustion in manufacturing of CAR T-cells.docx
Published 2025“…To address this need, in this work, we utilized a bioinspired, scalable, tunable platform to direct T-cell activation and decrease exhaustion during CAR T production.…”
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Participants enrollment.
Published 2025“…<div><p>Hypertension is a widespread and life-threatening condition affecting one-third of adults globally. In low- and middle-income countries, like Malawi, the burden of hypertension is escalating due to inadequate healthcare resources and lifestyle changes. …”
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KAP assessment scores (n = 422).
Published 2025“…<div><p>Hypertension is a widespread and life-threatening condition affecting one-third of adults globally. In low- and middle-income countries, like Malawi, the burden of hypertension is escalating due to inadequate healthcare resources and lifestyle changes. …”
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Image 1_Emapalumab for severe cytokine release syndrome in solid tumor CAR-T: a case report.tif
Published 2025“…Here we report a patient who received an investigational CAR-T product for metastatic castration-resistant prostate cancer who developed multi-drug refractory, life-threatening CRS, which was successfully treated with the interferon (IFN)-γ antagonist emapalumab. …”
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Presentation 1_HNF4α contributes to hepatic CAR dysfunction in polymicrobial sepsis.pptx
Published 2025“…Additionally, we show that CAR DNA binding is impaired, and we propose that HNF4α may regulate chromatin accessibility of CAR binding sites in sepsis. …”
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Data Sheet 1_GSTP1 improves CAR-T cell proliferation and cytotoxicity to combat lymphoma.zip
Published 2025“…Based on these findings, we engineered GSTP1 CAR-T cells, which exhibited improved functionality. …”
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Development of production methodologies for scFv-Fc conjugated critical reagents to support CAR-T clinical programs
Published 2025“…</p> <p>We highlight our approach in developing process conditions for CAR-T supporting conjugated critical reagents, where recombinant CAR scFv-hFc is the surrogate drug material to be conjugated. …”