يعرض 1 - 20 نتائج من 191 نتيجة بحث عن '(( traits ((larger decrease) OR (marked decrease)) ) OR ( via ca decrease ))', وقت الاستعلام: 0.45s تنقيح النتائج
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    Data Sheet 1_Long-term gabapentin treatment impairs cognitive function in aged mice via tau hyperphosphorylation.docx حسب Suyun Xia (22173550)

    منشور في 2025
    "…In the hippocampus of GBP-treated mice, increased levels of p-tau (S416) and p-tau (S262) were observed, together with increased CaMKIIα and decreased Sirt1 expression. AAV-mediated Sirt1 overexpression in the hippocampus or systemic administration of the Sirt1 activator resveratrol prevented cognitive impairment and tau hyperphosphorylation via enhancing Sirt1 activity in GBP-treated mice.…"
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    Proposed mechanism of action of ibuprofen (IBU) on hypoxic cancer cells. حسب Katarina Grossmannova (7543517)

    منشور في 2025
    "…<p>IBU impairs the STAT3 pathway and downregulates HIF-1α protein leading to impaired HIF-1 binding on the <i>CA9</i> promoter. The disruption of CA IX transcription results in a decreased level of CA IX on cancer cell membrane. …"
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    PCA. حسب Jerzy Paleolog (3220308)

    منشور في 2025
    الموضوعات:
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