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Showing 1 - 20 results of 3,866 for search '(( two ((spans decrease) OR (small decrease)) ) OR ( a ((largest decrease) OR (marked decrease)) ))', query time: 0.73s Refine Results
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    Geographical distribution of large cities and small cities. by Saul Estrin (8629173)

    Published 2024
    “…Representative cities are selected to ensure maximal coverage of continents. The Figure reveals two patterns: 1) the maximum level of innovation is higher in large cities (2.53) than in small cities (2.02); 2) among large cities in <b>a</b>, innovation levels in general decrease with nightlight density. …”
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    Group-level narrow- and broad-band spectral changes after hemispherotomy reveal a marked EEG slowing of the isolated cortex, robust across patients. by Michele Angelo Colombo (22446342)

    Published 2025
    “…Patients who received a temporo-parieto-occipital disconnection (squares with a black outline) displayed an overall similar pattern to that of patients who received a hemispherotomy (small dots). Significant contrasts are denoted by star symbols (* <i>P</i> < 0.05; ** <i>P</i> < 0.01; *** <i>P</i> < 0.001; **** <i>P</i> < 0.0001) over a bracket connecting the contrasted values, either the two cortices, or the post-pre difference against zero. …”
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    Novel Small-Molecule miR-124 Inducer Acts as “a Physiological Brake” of Inflammation in Ulcerative Colitis by Targeting the PIK3R2/PI3K/Akt Axis by Tiantian Wang (1688881)

    Published 2025
    “…This study identified FHND5032, a novel small-molecule miR-124 inducer, as a potent therapeutic candidate for UC. …”
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    Data and code from: Continental declines in North American small mammal populations by Alec Medd (20968740)

    Published 2025
    “…The resulting database is the largest collection of multi-year abundance data for North American small mammals. …”
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    Discovery of Novel [1,2,4]Triazolo[1,5‑<i>a</i>]pyrimidine Derivatives as Novel Potent S‑Phase Kinase-Associated Protein 2 (SKP2) Inhibitors for the Treatment of Cancer by Kaizhao Hu (15670612)

    Published 2024
    “…Pharmacological inhibition of Skp2 has exhibited promising antitumor activity. Herein, we present the design and optimization of a series of [1,2,4]triazolo[1,5-<i>a</i>]pyrimidine-based small molecules targeting Skp2. …”
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    Discovery of Novel [1,2,4]Triazolo[1,5‑<i>a</i>]pyrimidine Derivatives as Novel Potent S‑Phase Kinase-Associated Protein 2 (SKP2) Inhibitors for the Treatment of Cancer by Kaizhao Hu (15670612)

    Published 2024
    “…Pharmacological inhibition of Skp2 has exhibited promising antitumor activity. Herein, we present the design and optimization of a series of [1,2,4]triazolo[1,5-<i>a</i>]pyrimidine-based small molecules targeting Skp2. …”
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    Discovery of Novel [1,2,4]Triazolo[1,5‑<i>a</i>]pyrimidine Derivatives as Novel Potent S‑Phase Kinase-Associated Protein 2 (SKP2) Inhibitors for the Treatment of Cancer by Kaizhao Hu (15670612)

    Published 2024
    “…Pharmacological inhibition of Skp2 has exhibited promising antitumor activity. Herein, we present the design and optimization of a series of [1,2,4]triazolo[1,5-<i>a</i>]pyrimidine-based small molecules targeting Skp2. …”
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    Discovery of Novel [1,2,4]Triazolo[1,5‑<i>a</i>]pyrimidine Derivatives as Novel Potent S‑Phase Kinase-Associated Protein 2 (SKP2) Inhibitors for the Treatment of Cancer by Kaizhao Hu (15670612)

    Published 2024
    “…Pharmacological inhibition of Skp2 has exhibited promising antitumor activity. Herein, we present the design and optimization of a series of [1,2,4]triazolo[1,5-<i>a</i>]pyrimidine-based small molecules targeting Skp2. …”
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    Discovery of Novel [1,2,4]Triazolo[1,5‑<i>a</i>]pyrimidine Derivatives as Novel Potent S‑Phase Kinase-Associated Protein 2 (SKP2) Inhibitors for the Treatment of Cancer by Kaizhao Hu (15670612)

    Published 2024
    “…Pharmacological inhibition of Skp2 has exhibited promising antitumor activity. Herein, we present the design and optimization of a series of [1,2,4]triazolo[1,5-<i>a</i>]pyrimidine-based small molecules targeting Skp2. …”
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