<b>Chemical components, emission dynamics, and external immune functions of red palm weevil larval volatiles in response to changes in developmental stages and pathogen stress</b> by Can-Hui Ding (22140753)

“…However, the volatile compositions, emission patterns, and external immune functions of the red palm weevil (RPW), a major invasive pest, are largely unknown. In this study, we examined RPW larval volatiles, analyzing their chemical composition and emission patterns across developmental stages and under pathogen stress. …”

smFISH probe sequences used in this study. by Grace E. Johnson (21376787)

“…To define mechanisms underlying biofilm developmental transitions, we establish a single-molecule fluorescence in situ hybridization (smFISH) approach that enables accurate quantitation of spatiotemporal gene-expression patterns in biofilms at cell-scale resolution. smFISH analyses of <i>V. cholerae</i> biofilm regulatory and structural genes demonstrate that, as biofilms mature, overall matrix gene expression decreases, and simultaneously, a pattern emerges in which matrix gene expression becomes largely confined to peripheral biofilm cells. …”

Strains used in this study. by Grace E. Johnson (21376787)

“…To define mechanisms underlying biofilm developmental transitions, we establish a single-molecule fluorescence in situ hybridization (smFISH) approach that enables accurate quantitation of spatiotemporal gene-expression patterns in biofilms at cell-scale resolution. smFISH analyses of <i>V. cholerae</i> biofilm regulatory and structural genes demonstrate that, as biofilms mature, overall matrix gene expression decreases, and simultaneously, a pattern emerges in which matrix gene expression becomes largely confined to peripheral biofilm cells. …”

Water-saving strategies in rice farming entail cascading effects in prey-predator interactions across ecosystem boundaries by Néstor Pérez-Méndez (7845404)

“…<i>Synthesis and applications</i><i>:</i> These results show that introducing multiple drainage periods in rice fields (i.e., AWD) indirectly hampers terrestrial spider reproduction through limiting the emergence of potential preys from the aquatic to terrestrial boundaries. MSD resulted in a more conciliatory strategy as it largely reduces methane emissions and does not affect predator-prey interactions, thus it should be prioritized over AWD to minimize environmental trade-offs. …”

Data Sheet 1_Hyaluronan synthase 3 deficiency lowers the incidence of ruptures of abdominal aortic aneurysms by reducing monocyte infiltration.docx by Viola Niemann (22572638)

“…Critical pathomechanisms involve immune cell infiltration and degradation of the vascular extracellular matrix (ECM). Hyaluronan (HA), a major constituent of the ECM synthesized by three HA synthase isoenzymes (HAS1-3), plays a role in both processes. …”

Table 1_Integrated multi-omics analysis reveals the mechanisms of naringin in ameliorating high-fat diet-induced metabolic dysfunction-associated steatotic liver disease.doc by Wenping Sun (1465360)

“…However, its underlying mechanisms remain largely elusive.</p>Methods<p>In this study, we investigated the efficacy and underlying mechanisms of Nar in a mouse model of high-fat diet (HFD)-induced MASLD using integrated analyses of network pharmacology, molecular docking, hepatic lipidomics, and gut microbiota.…”

Deficiency of the UBE2C/F264 Axis Underlies Intrinsic Radioresistance in Cervical Carcinoma by Maowei Ni (15397932)

“…Intrinsic radiotherapy resistance remains a persistent challenge to the treatment of cervical cancer (CC), as the underlying mechanisms remain largely elusive. …”

Image 2_Low-frequency electroacupuncture attenuates methamphetamine-induced depressive-like behaviors and cognitive impairment via modulating neuroinflammation.tif by Jingyi Zhang (741111)

“…Electroacupuncture (EA) has shown promise in treating mental disorders linked to CNS damage, yet the effects of EA on METH-induced depressive-like behaviors and cognitive impairment and it’s underlying therapeutic mechanisms remain largely unclear.</p>Methods<p>In this study, a mouse model of METH-induced neuropsychiatric dysfunction was established by administering high-dose METH under elevated ambient temperature. …”

Image 6_Low-frequency electroacupuncture attenuates methamphetamine-induced depressive-like behaviors and cognitive impairment via modulating neuroinflammation.tif by Jingyi Zhang (741111)

“…Electroacupuncture (EA) has shown promise in treating mental disorders linked to CNS damage, yet the effects of EA on METH-induced depressive-like behaviors and cognitive impairment and it’s underlying therapeutic mechanisms remain largely unclear.</p>Methods<p>In this study, a mouse model of METH-induced neuropsychiatric dysfunction was established by administering high-dose METH under elevated ambient temperature. …”

Image 4_Low-frequency electroacupuncture attenuates methamphetamine-induced depressive-like behaviors and cognitive impairment via modulating neuroinflammation.tif by Jingyi Zhang (741111)

“…Electroacupuncture (EA) has shown promise in treating mental disorders linked to CNS damage, yet the effects of EA on METH-induced depressive-like behaviors and cognitive impairment and it’s underlying therapeutic mechanisms remain largely unclear.</p>Methods<p>In this study, a mouse model of METH-induced neuropsychiatric dysfunction was established by administering high-dose METH under elevated ambient temperature. …”

Image 5_Low-frequency electroacupuncture attenuates methamphetamine-induced depressive-like behaviors and cognitive impairment via modulating neuroinflammation.tif by Jingyi Zhang (741111)

“…Electroacupuncture (EA) has shown promise in treating mental disorders linked to CNS damage, yet the effects of EA on METH-induced depressive-like behaviors and cognitive impairment and it’s underlying therapeutic mechanisms remain largely unclear.</p>Methods<p>In this study, a mouse model of METH-induced neuropsychiatric dysfunction was established by administering high-dose METH under elevated ambient temperature. …”

Image 3_Low-frequency electroacupuncture attenuates methamphetamine-induced depressive-like behaviors and cognitive impairment via modulating neuroinflammation.tif by Jingyi Zhang (741111)

“…Electroacupuncture (EA) has shown promise in treating mental disorders linked to CNS damage, yet the effects of EA on METH-induced depressive-like behaviors and cognitive impairment and it’s underlying therapeutic mechanisms remain largely unclear.</p>Methods<p>In this study, a mouse model of METH-induced neuropsychiatric dysfunction was established by administering high-dose METH under elevated ambient temperature. …”

Image 1_Low-frequency electroacupuncture attenuates methamphetamine-induced depressive-like behaviors and cognitive impairment via modulating neuroinflammation.tif by Jingyi Zhang (741111)

“…Electroacupuncture (EA) has shown promise in treating mental disorders linked to CNS damage, yet the effects of EA on METH-induced depressive-like behaviors and cognitive impairment and it’s underlying therapeutic mechanisms remain largely unclear.</p>Methods<p>In this study, a mouse model of METH-induced neuropsychiatric dysfunction was established by administering high-dose METH under elevated ambient temperature. …”

Data Sheet 1_Trifolin inhibits the calcium-driven contraction pathway in vascular smooth muscle.pdf by Renfeng Li (126284)

“…<p>Trifolin, a bioactive component of the Qingda granule, has demonstrated significant antihypertensive potential; however, its precise mechanisms of action remain largely unknown. …”

Deficiency of the UBE2C/F264 Axis Underlies Intrinsic Radioresistance in Cervical Carcinoma by Maowei Ni (15397932)

“…Intrinsic radiotherapy resistance remains a persistent challenge to the treatment of cervical cancer (CC), as the underlying mechanisms remain largely elusive. …”

Deficiency of the UBE2C/F264 Axis Underlies Intrinsic Radioresistance in Cervical Carcinoma by Maowei Ni (15397932)

“…Intrinsic radiotherapy resistance remains a persistent challenge to the treatment of cervical cancer (CC), as the underlying mechanisms remain largely elusive. …”

Data Sheet 1_Distinct Arnica montana L. extracts modulate human T cell activation in different ways via differential inhibition of NFκB and NFAT pathways.zip by Karina M. Berschneider (14001561)

“…<p>Arnica montana L. (Arnica) has a long history of use in treating inflammation and soft tissue injury, yet its immunomodulatory mechanisms remain largely unexplored. …”

Image 1_Analgesic effect of Dahuang Fuzi Decoction in neuropathic pain through inhibiting TNF-α and PI3K-AKT signaling.jpeg by Jinglian Qu (10044263)

“…A chronic sciatic nerve compression injury (CCI) rat mode was used to assess the analgesic efficacy of DF for NeP. …”

Tropical fishes can benefit more from novel than familiar species interactions at their cold-range edges by Angus Mitchell (8391018)

“…Whether such novel species interactions facilitate or inhibit range extensions remains largely unknown.</p><p dir="ltr">2. We evaluated how range-extending tropical and co-shoaling temperate fishes modify their behaviours (aggression, foraging, and anti-predator) along a 2,000-km latitudinal gradient encapsulating tropical, subtropical and temperate reefs in a global ocean warming hotspot.…”

Data Sheet 1_Itaconate and obesity-related hormones promote tumor progression – new insights on metabolic dysfunction in early-onset colon cancer.docx by Katharina M. Scheurlen (21507602)

“…Introduction<p>Obesity is a strong risk factor for early-onset colon cancer (EOCC) and is associated with chronic inflammation largely mediated by macrophages. …”