Image_4_TRAPS mutations in Tnfrsf1a decrease the responsiveness to TNFα via reduced cell surface expression of TNFR1.tif by Takahiko Akagi (13138338)

“…The TNFR1 levels were increased in whole-cell lysates of TRAPS mutant macrophages, whereas the cell surface expression of TNFR1 was significantly decreased in TRAPS mutant macrophages. Taken together, TRAPS mutations did not augment the inflammatory responses to TNFα and LPS; instead, they suppressed the response to TNFα via decreased cell surface expression of TNFR1. …”

Image_7_TRAPS mutations in Tnfrsf1a decrease the responsiveness to TNFα via reduced cell surface expression of TNFR1.tif by Takahiko Akagi (13138338)

“…The TNFR1 levels were increased in whole-cell lysates of TRAPS mutant macrophages, whereas the cell surface expression of TNFR1 was significantly decreased in TRAPS mutant macrophages. Taken together, TRAPS mutations did not augment the inflammatory responses to TNFα and LPS; instead, they suppressed the response to TNFα via decreased cell surface expression of TNFR1. …”

Image_3_TRAPS mutations in Tnfrsf1a decrease the responsiveness to TNFα via reduced cell surface expression of TNFR1.tif by Takahiko Akagi (13138338)

“…The TNFR1 levels were increased in whole-cell lysates of TRAPS mutant macrophages, whereas the cell surface expression of TNFR1 was significantly decreased in TRAPS mutant macrophages. Taken together, TRAPS mutations did not augment the inflammatory responses to TNFα and LPS; instead, they suppressed the response to TNFα via decreased cell surface expression of TNFR1. …”

Image_6_TRAPS mutations in Tnfrsf1a decrease the responsiveness to TNFα via reduced cell surface expression of TNFR1.tif by Takahiko Akagi (13138338)

“…The TNFR1 levels were increased in whole-cell lysates of TRAPS mutant macrophages, whereas the cell surface expression of TNFR1 was significantly decreased in TRAPS mutant macrophages. Taken together, TRAPS mutations did not augment the inflammatory responses to TNFα and LPS; instead, they suppressed the response to TNFα via decreased cell surface expression of TNFR1. …”

Image_2_TRAPS mutations in Tnfrsf1a decrease the responsiveness to TNFα via reduced cell surface expression of TNFR1.tif by Takahiko Akagi (13138338)

“…The TNFR1 levels were increased in whole-cell lysates of TRAPS mutant macrophages, whereas the cell surface expression of TNFR1 was significantly decreased in TRAPS mutant macrophages. Taken together, TRAPS mutations did not augment the inflammatory responses to TNFα and LPS; instead, they suppressed the response to TNFα via decreased cell surface expression of TNFR1. …”

SRC-3 treatment decreased tumor growth in a Jeko-1 ibrutinib resistant mouse model. by Imani Bijou (18275174)

Decreased self-inhibition of genotypes carrying the cooperation-associated allele along a density gradient. by Samuel E. Wuest (14192695)

Innovation and night light in large and small cities. by Saul Estrin (8629173)

(A) Shape of the osteotomies during the 3-step MIPS drilling procedure. by Marsel Ganeyev (21453399)

Geographical distribution of large cities and small cities. by Saul Estrin (8629173)

“…The Figure reveals two patterns: 1) the maximum level of innovation is higher in large cities (2.53) than in small cities (2.02); 2) among large cities in <b>a</b>, innovation levels in general decrease with nightlight density. …”

Deletion of TAL does not decrease GNG flux. by Julie Kovářová (4114573)

Colistin-phage combinations decrease antibiotic resistance in <i>Acinetobacter baumannii</i> via changes in envelope architecture by Xiaoqing Wang (514179)

The dynamic of a <i>Q</i> = 3 community. by Immanuel Meyer (12306666)

Increased isolated activity via Piezo1 decreases DRG cell divisions and reduces response to cold stimulus. by Jacob P. Brandt (11725253)

Hr-GAL1 and 3 decreases intracellular galectin-1 and -3 level via exocytosis and proteasomal degradation. by Anna Hillenmayer (12280007)

Gross photography and construct weight for initial chondrogenic screening. by Melissa A. MacIver (12850566)

Subjects:

Transcriptional analysis of chondrogenic and osteogenic genes. by Melissa A. MacIver (12850566)

Subjects:

Observation of a Large Slip Effect in the Nanoscale Flow of Highly Viscous Supercooled Liquid Metals by Jun-Xiang Xiang (16751412)

“…Here, we report the observation of a large boundary slip in the nanoscale flow of highly viscous supercooled liquid metals (with viscosities of ≲10⁸ Pa s), enabled by the hydrophobic treatment of smooth nanochannels. …”

Observation of a Large Slip Effect in the Nanoscale Flow of Highly Viscous Supercooled Liquid Metals by Jun-Xiang Xiang (16751412)

“…Here, we report the observation of a large boundary slip in the nanoscale flow of highly viscous supercooled liquid metals (with viscosities of ≲10⁸ Pa s), enabled by the hydrophobic treatment of smooth nanochannels. …”

<b>Supporting data for manuscript</b> "<b>Voluntary locomotion induces an early and remote hemodynamic decrease in the large cerebral veins</b>" by Kira Shaw (18796168)

“…<p dir="ltr">The CSV file 'Eyreetal_DrainingVein_SourceData' contains the averaged time series traces and extracted metrics from individual experiments used across Figures 1-5 in the manuscript "Voluntary locomotion induces an early and remote hemodynamic decrease in the large cerebral veins". The following acronyms included in the CSV file are defined as follows: Hbt is total hemoglobin, Art is artery region, DV is draining vein region, WV is whisker vein region, SEM is standard error mean, TS is time series, max peak is maximum peak, min peak is minima, AUC is area under the curve, WT is wild-type, AD is Alzheimer's disease, ATH is atherosclerosis and MIX is mixed AD/atherosclerosis. …”