Image_10_Topoisomerase 2B Decrease Results in Diastolic Dysfunction via p53 and Akt: A Novel Pathway.TIF by Rohit Moudgil (540119)

Image_12_Topoisomerase 2B Decrease Results in Diastolic Dysfunction via p53 and Akt: A Novel Pathway.TIFF by Rohit Moudgil (540119)

Image_15_Topoisomerase 2B Decrease Results in Diastolic Dysfunction via p53 and Akt: A Novel Pathway.TIFF by Rohit Moudgil (540119)

Image_1_Topoisomerase 2B Decrease Results in Diastolic Dysfunction via p53 and Akt: A Novel Pathway.TIFF by Rohit Moudgil (540119)

Image_9_Topoisomerase 2B Decrease Results in Diastolic Dysfunction via p53 and Akt: A Novel Pathway.TIF by Rohit Moudgil (540119)

Image_14_Topoisomerase 2B Decrease Results in Diastolic Dysfunction via p53 and Akt: A Novel Pathway.TIFF by Rohit Moudgil (540119)

Image_5_Topoisomerase 2B Decrease Results in Diastolic Dysfunction via p53 and Akt: A Novel Pathway.TIF by Rohit Moudgil (540119)

Image_2_Topoisomerase 2B Decrease Results in Diastolic Dysfunction via p53 and Akt: A Novel Pathway.TIFF by Rohit Moudgil (540119)

Sevoflurane induces cognitive impairment in young mice via autophagy by Xiaoning Wang (16150)

“…We used different groups of mice for behavioral testing via the Morris Water Maze from P31 to P37.</p><p>Results</p><p>The anesthetic sevoflurane increased the level of LC3-II and ratio of LC3-II/LC3-I, decreased the p62 level in the hippocampus of the young mice, and induced cognitive impairment in the mice. 3-Methyladenine, the inhibitor of autophagy, attenuated the activation of autophagy and ameliorated the cognitive impairment induced by sevoflurane in the young mice.…”

AMPK regulates Fet-A expression by proteosomal degradation and decreased C/EBP beta expression. by Vishal Kothari (12511601)

Animation displaying S100A1−MDM2 complex generated via the HADDOCK program. by Deepu Dowarha (5673440)

Dynorphin Neuropeptides Decrease Apparent Proton Affinity of ASIC1a by Occluding the Acidic Pocket by Lilia Leisle (11356934)

“…Prolonged acidosis, as it occurs during ischemic stroke, induces neuronal death via acid-sensing ion channel 1a (ASIC1a). Concomitantly, it desensitizes ASIC1a, highlighting the pathophysiological significance of modulators of ASIC1a acid sensitivity. …”

Dynorphin Neuropeptides Decrease Apparent Proton Affinity of ASIC1a by Occluding the Acidic Pocket by Lilia Leisle (11356934)

“…Prolonged acidosis, as it occurs during ischemic stroke, induces neuronal death via acid-sensing ion channel 1a (ASIC1a). Concomitantly, it desensitizes ASIC1a, highlighting the pathophysiological significance of modulators of ASIC1a acid sensitivity. …”

Video_1_Topoisomerase 2B Decrease Results in Diastolic Dysfunction via p53 and Akt: A Novel Pathway.MP4 by Rohit Moudgil (540119)

Video_1_Topoisomerase 2B Decrease Results in Diastolic Dysfunction via p53 and Akt: A Novel Pathway.MP4 by Rohit Moudgil (540119)

Video_2_Topoisomerase 2B Decrease Results in Diastolic Dysfunction via p53 and Akt: A Novel Pathway.MP4 by Rohit Moudgil (540119)

Video_2_Topoisomerase 2B Decrease Results in Diastolic Dysfunction via p53 and Akt: A Novel Pathway.MP4 by Rohit Moudgil (540119)

Data Sheet 1_Nicorandil reduces the antimicrobial effectiveness of polymyxin E against Klebsiella pneumoniae by decreasing reactive oxygen species accumulation.pdf by Rongqing Zhu (22261801)

“…The release of NO by nicorandil was confirmed via reactive nitrogen species (RNS) assays. The impact of NO on oxidative stress responses induced by polymyxin E was evaluated using reactive oxygen species (ROS) assays and RT-qPCR. …”

PRRSV enters MARC-145 cells via macropinocytosis and rottlerin blocks the macropinocytosis by decreasing actin polymerization. by Yeonglim Kang (21395261)

Protein degradation via the ubiquitin proteasome activity decreases with age and castration tends to increase the activity of this system. by Arik Davidyan (10450896)