DataSheet_1_GPCR19 Regulates P2X7R-Mediated NLRP3 Inflammasomal Activation of Microglia by Amyloid β in a Mouse Model of Alzheimer’s Disease.docx by Jahirul Islam (11280516)

“…<p>Amyloid β (Aβ) and/or ATP activate the NLRP3 inflammasome (N3I) via P2X7R in microglia, which is crucial in neuroinflammation in Alzheimer’s disease (AD). …”

Synthesis of Iridaboratranes Bearing Phosphine-Tethered Borane: Reversible CO/PR₃ (R = Me, OMe, OEt) Substitution Reactions Induced by a σ-Electron-Acceptor Borane Ligan... by Hajime Kameo (1612654)

“…The borane ligand extracts a significant amount of electron density from the iridium center, but the iridium center maintains an electron density similar to that of the boron-free compound <b>2-Ir</b> by decreasing π back-donation from Ir to CO and strengthening the donation from the phosphorus atom (or by weakening the d_metal–σ*_P–R interaction). …”

DataSheet1_Effects of modified Danggui Sini Decoction as adjuvant therapy for angina pectoris in coronary heart disease: a systematic review and meta-analysis based on randomised c... by He Wang (250350)

“…The quality of included studies was assessed using the Cochrane Handbook version 5.1, and meta-analysis was executed via RevMan 5.4 software.</p>Results<p>Thirteen studies encompassing 1,232 participants were incorporated. …”

Morphological features vary as cells divide. by Kerry A. Geiler-Samerotte (9248817)

“…(B) Centered data for 11, 23, and 44 unbudded, small-budded, and large-budded cells, respectively, show how Wishbone sorts live cells in a way that recapitulates the actual time series. …”

Electron Transfer between Two Silyl-Substituted Phenylene Rings:  EPR/ENDOR Spectra, DFT Calculations, and Crystal Structure of the One-Electron Reduction Compound of a Di(<i>m</i>... by Cosmina Dutan (2968782)

“…Reduction of a solution of octamethylcyclo-di(<i>m</i>-silylphenylenedisiloxane) <b>4</b> in THF on a potassium mirror leads to EPR/ENDOR spectra characterized by a large coupling (<i>∼</i>20 MHz) with two protons, similar to the spectra obtained after reduction of the <i>m</i>-disilylbenzene derivative <b>5</b>, consistent with a localization of the extra electron on a single ring of <b>4</b>. …”

Table_3_Extremes in Benthic Ecosystem Services; Blue Carbon Natural Capital Shallower Than 1000 m in Isolated, Small, and Young Ascension Island’s EEZ.xlsx by David K. A. Barnes (7828889)

“…Ascension Island and its seamounts are small, isolated and relatively young, yet harbor patchily dense life. Large areas of these waters are soon to be designated as a major Marine Protected Area. …”

Table_1_Extremes in Benthic Ecosystem Services; Blue Carbon Natural Capital Shallower Than 1000 m in Isolated, Small, and Young Ascension Island’s EEZ.xlsx by David K. A. Barnes (7828889)

“…Ascension Island and its seamounts are small, isolated and relatively young, yet harbor patchily dense life. Large areas of these waters are soon to be designated as a major Marine Protected Area. …”

Table_2_Extremes in Benthic Ecosystem Services; Blue Carbon Natural Capital Shallower Than 1000 m in Isolated, Small, and Young Ascension Island’s EEZ.xlsx by David K. A. Barnes (7828889)

“…Ascension Island and its seamounts are small, isolated and relatively young, yet harbor patchily dense life. Large areas of these waters are soon to be designated as a major Marine Protected Area. …”

Image_1_Acid-Sensing Ion Channel 1/Calpain1 Activation Impedes Macrophage ATP-Binding Cassette Protein A1-Mediated Cholesterol Efflux Induced by Extracellular Acidification.TIF by Yuan-Mei Wang (11530463)

“…Background<p>Extracellular acidification is a common feature of atherosclerotic lesions, and such an acidic microenvironment impedes ATP-binding cassette transporter A1 (ABCA1)-mediated cholesterol efflux and promotes atherogenesis. …”

Table 1_Polarization of Vδ2 T cells to a Th2-like phenotype promotes plasmablast differentiation and possesses pro-fibrotic properties in IgG4-related disease.docx by Jieqiong Li (327149)

“…</p>Conclusion<p>Within the IL-21-rich microenvironment of IgG4-RD, peripheral Vδ2 T cells acquire a Th2-like phenotype via the IL-21—STAT3—Blimp-1—GATA3 pathway. …”

DataSheet1_Isoforskolin Alleviates AECOPD by Improving Pulmonary Function and Attenuating Inflammation Which Involves Downregulation of Th17/IL-17A and NF-κB/NLRP3.pdf by Chuang Xiao (11208372)

“…In conclusion, ISOF alleviates AECOPD by improving pulmonary function and attenuating inflammation via the downregulation of proinflammatory cytokines, Th17/IL-17 A, and NF-κB/NLRP3 pathways.…”

Data_Sheet_1_Impact of Fermented Corn–Soybean Meal on Gene Expression of Immunity in the Blood, Level of Secretory Immunoglobulin A, and Mucosa-Associated Bacterial Community in th... by Junfeng Lu (820760)

“…Moreover, sequencing of 16S rRNA genes in duodenal mucosa samples indicated that the FF diet had a lower proportion of Tenericutes (P < 0.05) in the duodenal mucosa-associated microbiota, and FF significantly increased the percentage of Rikenellaceae and Christensenellaceae but decreased the abundance of Lachnospiraceae (P < 0.05) in the colonic mucosa-associated microbiota. …”

Data Sheet 1_Deciphering a missing piece of the branched-chain amino acids uptake puzzle: YhjE is an L-isoleucine and L-valine transporter in Escherichia coli K-12.docx by Sergey V. Molev (22769330)

“…Hydroxylamine mutagenesis yielded yhjE variants that permitted growth under L-leucine limitation; across tested alleles, L-leucine uptake increased while L-isoleucine uptake decreased, demonstrating reprogramming of substrate preference via discrete substitutions. …”

DataSheet1_Pan-Cancer Analyses Identify the CTC1-STN1-TEN1 Complex as a Protective Factor and Predictive Biomarker for Immune Checkpoint Blockade in Cancer.PDF by Lishuai Wang (12247556)

“…However, the detailed mechanisms of CST regulation in cancer remain largely unknown. Here, we perform a comprehensive analysis of CST across 33 cancer types using multi-omic data from The Cancer Genome Atlas. …”

Data_Sheet_1_Lateralized brain activities in subcortical vascular mild cognitive impairment with differential Chinese medicine patterns: A resting-state functional magnetic resonan... by Jianjun Wang (67330)

“…All patients were categorized into either the EP group (n = 16) and the DP group (n = 21) based on a quantitative CM scale. The fractional amplitude of low-frequency fluctuation (fALFF) value was used to make comparisons between different subgroups.…”

Impact of the announcement and implementation of the UK Soft Drinks Industry Levy on sugar content, price, product size and number of available soft drinks in the UK, 2015-19: A co... by Peter Scarborough (329722)

“…Whilst the product size of branded high levy and low levy drinks barely changed after implementation of the SDIL (−7 mL [−23 to 11 mL] and 16 mL [6–27ml], respectively), there were large changes to product size of own-brand drinks with an increase of 172 mL (133–214 mL) for high levy drinks and a decrease of 141 mL (111–170 mL) for low levy drinks. …”

DAF-16/FoxO Directly Regulates an Atypical AMP-Activated Protein Kinase Gamma Isoform to Mediate the Effects of Insulin/IGF-1 Signaling on Aging in <i>Caenorhabditis elegans</i> by Jennifer M. A. Tullet (244402)

“…Knock down of <i>aakg-4</i> expression caused a transient decrease in activation of expression in multiple DAF-16 target genes. …”

Global, regional, and national age-sex-specific burden of diarrhoeal diseases, their risk factors, and aetiologies, 1990–2021, for 204 countries and territories: a systematic analy... by Hmwe Hmwe, Kyu

“…The most pronounced decline was in children younger than 5 years, with a 79·2% (72·4–84·6) decrease in diarrhoeal deaths. …”
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Data_Sheet_1_Canine Transforming Growth Factor-β Receptor 2-Ig: A Potential Candidate Biologic for Melanoma Treatment That Reverses Transforming Growth Factor-β1 Immunosuppression.... by Hiroto Takeuchi (8959853)

“…<p>Cancer cells can evade host immune systems via multiple mechanisms. Transforming growth factor beta 1 (TGF-β1) is an immunosuppressive cytokine that induces regulatory T cell (Tregs) differentiation and is involved in immune evasion mechanisms in cancer. …”

Data_Sheet_1_The Diacylglycerol Analogs OAG and DOG Differentially Affect Primary Events of Pheromone Transduction in the Hawkmoth Manduca sexta in a Zeitgebertime-Dependent Manner... by Petra Gawalek (409771)

“…<p>For the hawkmoth Manduca sexta accumulating evidence suggests that pheromone transduction acts via a metabotropic signal transduction cascade, with G-protein-dependent phospholipase C (PLC) activations generating diacylglycerol (DAG) and inositol trisphosphate as the primary events in hawkmoth pheromone transduction. …”