Parameter sensitivity analysis and its correspondence with mutations in the extended pathway. by Jia Chen (8203)

“…<p>(A) The change in the saddle-node bifurcation point in response to a 20% increase or decrease of each parameter of the extended apoptosis pathway. …”

Model summarizing main findings. by K. M. Moyes (2852147)

“…This is also supported by the significant decrease in expression of negative acute phase proteins at this time (<a href="http://www.plosone.org/article/info:doi/10.1371/journal.pone.0157480#pone.0157480.s004" target="_blank">S4 Fig</a>). …”

Intestinal overexpression of <i>mir-2</i> enhances DA neurodegeneration and is attenuated by AIM-100 when <i>sid-1</i> is wildtype. by Anthony L. Gaeta (13272609)

“…When SID-3 is inhibited by AIM-100, evidence suggests that endocytosis of SID-1 is increased, resulting in a decrease of <i>mir-2</i> import into cells, and conversely increasing the abundance of upregulated transcripts that contribute to the DA neuroprotection observed. …”

Supporting data for “Soft robotic gloves for elderly assistance” by Hao Liu (11433595)

“…A 5 kg dumbbell lifting test is designed to evaluate the assistance performance of the robotic glove via the muscle activities, grip strength decrease ratio, and lifting time, which proves the practicability of the robotic glove at the physiological level, functional level, and behavior level, respectively.…”

CD86 and IL-12p70 Are Key Players for T Helper 1 Polarization and Natural Killer Cell Activation by Toll-Like Receptor-Induced Dendritic Cells by Felix S. Lichtenegger (139363)

“…Functionally, these signals translated into an increase in IFN-γ secreting Th1 cells and a decrease in regulatory T cells. T cell activation and polarization were dependent on IL-12p70 and CD86, but remarkably not on CD80 signaling. …”

Data_Sheet_1_Modulation of Septo-Hippocampal Neural Responses in Anesthetized and Behaving Rats by Septal AMPA Receptor Mechanisms.docx by Khairunisa Mohamad Ibrahim (10921080)

“…The current results showed that microinjection of AMPAR antagonist, NBQX (2,3-dihydroxy-6-nitro-7-sulfamoyl-benzo[f]quinoxaline-2,3-dione, 20 μg/μl, 0.5 μl), evoked a decrease in the frequency of theta activity evoked by various means in anesthetized and behaving rat. …”

I-Mutant results for selected nsSNPs in the TRIM22 protein. by Jenna N. Kelly (591069)

“…  =  number of deleterious predictions; nsSNPs with 4 or more deleterious predictions are considered high-risk nsSNPs, while nsSNPs with less than 4 deleterious predictions are considered low-risk; DDG: free energy change value in Kcal/mol (>0 increase, <0 decrease, >0.5 large increase, <−0.5 large decrease); Sign of DDG: the direction of the change (increase or decrease); The reliability index (RI) from 0–9 is shown in parentheses, where 0 is the lowest RI and 9 is the highest); PTM: predicted post-translational modification site; ConSurf results are shown in the last column (number represents the conservation score (CS) from 1–9, letter represents whether the residue was predicted to be exposed (e) or buried (b), putative functional residues are indicated with bold text; whereas putative structural residues are indicated with italicized text (<a href="http://www.plosone.org/article/info:doi/10.1371/journal.pone.0101436#pone.0101436.s001" target="_blank">Figure S1</a>); Sites with an additional ConSurf result in parentheses are located next to putative functional (9e) or structural (9b) residues; nsSNPs with the largest predicted stability decreases (DDG <−1.0) that also have a RI score of ≥5 are indicated with an asterisk.…”

Nluc sensitivity and cellular detection limit in vitro, in vivo and ex vivo. by John D. Ventura (8087951)

“…(F) In vivo and ex vivo Nluc signal detection limit in BALB/c mice infected subcutaneously via the footpad as well as intravenously via the retro-orbital route with decreasing concentrations of Friend MLV pMIG.Nluc.IRES.GFP virus for delivery to the popliteal lymph node and spleen, respectively. …”

Data_Sheet_1_Developmental Changes in ANS Precision Across Grades 1–9: Different Patterns of Accuracy and Reaction Time.pdf by Sergey Malykh (8395728)

“…The patterns of change were estimated via mixed-effect growth models. The results revealed that in the first cohort, the average accuracy increased from grade 1 to grade 5 following a non-linear pattern and that the rate of growth slowed after grade 3 (7–9 years old). …”

Direct downstream gene targets of the C/EBP-ε transcription factor. by Carolyn Glass (427882)

“…The x-axis is the significantly downregulated gene and the y-axis denotes reads per million on RNA-Seq analysis. <b>a)</b> In DA-1 <i>Evi1</i> overexpressed cells, <i>Serpinb2</i> had an 11.4-fold decrease (p = 0.0006), <i>Myc</i> had a 2.5-fold decrease (p = 0.04), <i>Lcn2</i> had a 3.4-fold decrease (p = 0.001), <i>Epx</i> had a 13.5-fold decrease (p = 0.0003). …”

<i>FMR4</i> affects proliferation in human cells. by Ahmad M. Khalil (38346)

“…<p>(A) Cell proliferation assay showing that the knockdown of <i>FMR4</i> via three distinct siRNAs in HEK-293T cells, but not knockdown of <i>FMR1</i>, resulted in decrease in cell proliferation in comparison to cells which are treated with a negative control siRNA. …”

S1 Data - by Allisson Dantas de Oliveira (17448081)

“…An average time of 27.00 ± 2.58 seconds is required to auto-focus a single FoV. Auto-focus evaluation demonstrates a mean average maximum Laplacian value of 11.83 with tested images. …”

Quantitative disruption of ER-PM contacts in Δ-s-tether cells. by Evan Quon (5244278)

“…It interacts with the PM via its C-terminal PI(4,5)P₂-binding polybasic region (++) [<a href="http://www.plosbiology.org/article/info:doi/10.1371/journal.pbio.2003864#pbio.2003864.ref034" target="_blank">34</a>]. …”

Data_Sheet_1_Striatal Volume Increase After Six Weeks of Selective Dopamine D2/3 Receptor Blockade in First-Episode, Antipsychotic-Naïve Schizophrenia Patients.docx by Helle G. Andersen (8869196)

“…Striatal increase was predicted by amisulpride dose, but not by either D_2/3R occupancy or baseline symptom severity. A significant reduction in symptom severity was observed at a mean dose of 233.3 (SD = 109.9) mg, corresponding to D_2/3R occupancy of 44.65%. …”

Difference between cystatin C- and creatinine-based estimated glomerular filtration rate and incident hypertension and the mediating role of Triglyceride Glucose Index by Zixuan Zhang (6957035)

“…During a mean follow-up period of 5.0 years, 613 new cases of hypertension occurred. …”

Table_2_The Impact of the COVID-19 Pandemic on Women’s Reproductive Health.docx by Niamh Phelan (10450682)

“…There was no change in the median cycle length (28 days) or days of bleeding (5) but there was a wider variability of cycle length (p = 0.01) and a 1 day median decrease in the minimum (p < 0.0001) and maximum (p = 0.009) cycle length. …”

Table_2_The Impact of the COVID-19 Pandemic on Women’s Reproductive Health.docx by Phelan Niamh (10342460)

“…There was no change in the median cycle length (28 days) or days of bleeding (5) but there was a wider variability of cycle length (p = 0.01) and a 1 day median decrease in the minimum (p < 0.0001) and maximum (p = 0.009) cycle length. …”

Table_1_The Impact of the COVID-19 Pandemic on Women’s Reproductive Health.docx by Niamh Phelan (10450682)

“…There was no change in the median cycle length (28 days) or days of bleeding (5) but there was a wider variability of cycle length (p = 0.01) and a 1 day median decrease in the minimum (p < 0.0001) and maximum (p = 0.009) cycle length. …”

Table_1_The Impact of the COVID-19 Pandemic on Women’s Reproductive Health.docx by Phelan Niamh (10342460)

“…There was no change in the median cycle length (28 days) or days of bleeding (5) but there was a wider variability of cycle length (p = 0.01) and a 1 day median decrease in the minimum (p < 0.0001) and maximum (p = 0.009) cycle length. …”

Datasheet1_Comparison of clinical and echocardiographic outcomes between mini-thoracotomy transatrial LuX-Valve transcatheter and surgical tricuspid valve replacement.pdf by Lei Huang (35191)

“…All TTVR patients received the LuX-Valve via a mini-thoracotomy and transatrial approach. …”