Heat-Shock Mediated Overexpression of HNF1β Mutations Has Differential Effects on Gene Expression in the <em>Xenopus</em> Pronephric Kidney by Kathrin Sauert (177290)

“…Heat-shock activation of the mutant HNF1B variants P328L329del and A263insGG resulted in malformations of various organs and the affected larvae developed large edemas. …”

Table_1_Infants Younger Than 90 Days Admitted for Late-Onset Sepsis Display a Reduced Abundance of Regulatory T Cells.docx by Ingmar Fortmann (9301351)

“…</p>Methods<p>We performed an exploratory, single center study between January 1^st, 2019 and June 1^st, 2021. …”

DataSheet_1_Construction of a prognostic 6-gene signature for breast cancer based on multi-omics and single-cell data.docx by Zeyu Xing (4381777)

“…Background<p>Breast cancer (BC) is one of the females’ most common malignant tumors there are large individual differences in its prognosis. …”

DataSheet_1_Invasive alien plants are phylogenetically distinct from other alien species across spatial and taxonomic scales in China.zip by Achyut Kumar Banerjee (7137815)

“…Introduction<p>Phylogenetic relatedness is one of the important factors in the community assembly process. …”

DataSheet_1_Genetically predicted levels of folate, vitamin B12, and risk of autoimmune diseases: A Mendelian randomization study.docx by Hong Yang (37298)

“…</p>Results<p>We found that a higher genetically determined serum folate level per one standard deviation (SD) was associated with a decreased risk of vitiligo by the IVW method [odds ratios (OR) = 0.47; 95% confidence interval (CI): 0.32–0.69; P = 1.33 × 10^-4]. …”

Data Sheet 1_Obstetric and perinatal outcomes in pregnancies conceived with donor versus partner sperm: a systematic review and meta-analysis.doc by Junjie Liu (193511)

“…Donor sperm was linked to better clinical pregnancy rates (RR 1.27, 95% CI 1.08–1.48) and decreased incidences of biochemical pregnancy (RR 0.85, 95% CI 0.81–0.88), miscarriage (RR 0.91, 95% CI 0.84–1.00), very preterm birth (RR 0.88, 95% CI 0.80–0.96), and very low birth weight (RR 0.89, 95% CI 0.81–0.98) compared with partner sperm. …”

Presentation_1_Retinal and Choroidal Vascular Perfusion and Thickness Measurement in Diabetic Retinopathy Patients by the Swept-Source Optical Coherence Tomography Angiography.pdf by Tingting Liu (267387)

Image 1_Inflammation mediated brain damage and cytokine expression in a maternally derived murine model for preterm hypoxic-ischemic encephalopathy.tiff by Tyler C. Hillman (13030476)

“…MAP2 expression was significantly decreased (p < 0.05) between 1.5–6.0 mm of the brain compared to Saline-Hypoxia and Naïve animals. …”

Data_Sheet_1_Temporal Bacterial Surveillance of Salmon Aquaculture Sites Indicates a Long Lasting Benthic Impact With Minimal Recovery.pdf by Joost T. P. Verhoeven (479712)

“…Samples within the high impact group were most often collected directly under cages, whereas those in the intermediate impact group were mainly sampled from 20 to 40 m from cages. Large scale phylum shifts (increases of Bacteroidetes, Firmicutes, Spirochaetes, and decreases in Proteobacteria and Epsilonbacteraeota) and a decline in bacterial diversity were observed in the high impact cluster, indicating significant ecological change. …”

Table1_Hydrogeochemistry of Hot Springs and the 2018 Mojiang M 5.9 Earthquake-Related Chemical Changes in the Simao Basin, China.docx by Qilin Li (535447)

Image_1_Infants Younger Than 90 Days Admitted for Late-Onset Sepsis Display a Reduced Abundance of Regulatory T Cells.jpeg by Ingmar Fortmann (9301351)

“…</p>Methods<p>We performed an exploratory, single center study between January 1^st, 2019 and June 1^st, 2021. …”

DataSheet1_Decadal variability of precipitation over the Tibetan Plateau modulated by the 11-year solar cycle over the past millennium.docx by Ying Hu (14950)

DataSheet1_Training machine learning models with synthetic data improves the prediction of ventricular origin in outflow tract ventricular arrhythmias.PDF by Ruben Doste (13239303)

“…However, the reported accuracy decreases when tested with different datasets. Machine learning algorithms can automatize the process and improve generalization, but their performance is hampered by the lack of large enough OTVA databases. …”

Data Sheet 1_Association between the triglyceride-glucose-waist-to-height ratio and cardiovascular disease in Chinese adults with sarcopenia or probable sarcopenia.docx by Wei Huang (36889)

“…Adjusted Cox models revealed that higher TyG-WHtR was independently associated with increased CVD risk: each one-unit increase corresponded to an 11% higher CVD risk (HR 1.11, 95% CI 1.01–1.22) and a 25% higher stroke risk (HR 1.25, 95% CI 1.06–1.47). …”

Table_1_Calorie-restricted diet mitigates weight gain and metabolic abnormalities in obese women with schizophrenia: a randomized controlled trial.DOC by Lei Zhang (38117)

“…Compared to the normal diet, adherence to the CRD significantly decreased body weight (2.38 ± 1.30 kg), body mass index (0.94 ± 0.52 kg/m²), waist circumference (4.34 ± 2.75 cm), hip circumference (3.37 ± 2.36 cm), mid-upper circumferences, triceps skin-fold thickness, fat mass and free fat mass with large effect sizes (p = <0.001, ηp² range between 0.145 and 0.571), as well as total cholesterol (0.69 ± 0.70 mmol/L) with a medium effect size (p = 0.028, ηp² = 0.054). …”

DataSheet_1_Age at first birth, age at menopause, and risk of ovarian cyst: a two-sample Mendelian randomization study.xlsx by Qian Su (3112242)

“…However, ANM has a positive correlation with the OC (IVW Beta: 0.05, OR: 1.05, 95% CI: 1.03–1.08, p = 8.38 × 10⁻⁶). …”

Image_1_P2x7 Receptor Signaling Blockade Reduces Lung Inflammation and Necrosis During Severe Experimental Tuberculosis.tif by Igor Santiago-Carvalho (10748994)

“…The effector CD4⁺ T cell population also decreased, but IFN-γ production by lung cells increased. …”

Data_Sheet_1_Spatial and Temporal Ecological Uniqueness of Andean Diatom Communities Are Correlated With Climate, Geodiversity and Long-Term Limnological Change.docx by Xavier Benito (4046333)

“…Over millennial time scales, decomposing temporal trends of beta diversity components showed different trajectories of lake diatom diversity as response of environmental change: i) increased hydroclimatic variability (as inferred by decreased temperature seasonality) mediating higher contribution of richness to local beta diversity patterns ca. 1000 years ago in Ecuador Andean lakes and ii) lake-specific temporal beta diversity trends for the last ca. 200 years, indicating that biotic homogenization is not widespread across the tropical Andes. …”

DataSheet_1_Macrophage-Regulatory T Cell Interactions Promote Type 2 Immune Homeostasis Through Resistin-Like Molecule α.pdf by Jiang Li (272926)

Image_1_Evidence for genetic causal relationships between gut microbiome, metabolites, and myasthenia gravis: a bidirectional Mendelian randomization study.jpeg by Dandan Sheng (3574232)

“…</p>Methods<p>Summary-level genetic datasets from large-scale genome-wide association studies regarding 196 gut microbial taxa from the MiBioGen consortium (n=18,340), 72 derived metabolites from the TwinsUK and KORA studies (n=7,824), and antiacetylcholine receptor (AChR) antibody-positive MG (case=1,873, control=36,370) were employed for MR causal estimates. …”