بدائل البحث:
larger decrease » marked decrease (توسيع البحث)
large decrease » marked decrease (توسيع البحث), large increases (توسيع البحث), large degree (توسيع البحث)
a decrease » _ decrease (توسيع البحث), _ decreased (توسيع البحث), _ decreases (توسيع البحث)
via large » a large (توسيع البحث)
larger decrease » marked decrease (توسيع البحث)
large decrease » marked decrease (توسيع البحث), large increases (توسيع البحث), large degree (توسيع البحث)
a decrease » _ decrease (توسيع البحث), _ decreased (توسيع البحث), _ decreases (توسيع البحث)
via large » a large (توسيع البحث)
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The ORF7a protein of SARS-CoV-2 initiates autophagy and limits autophagosome-lysosome fusion via degradation of SNAP29 to promote virus replication
منشور في 2022"…However, how SARS-CoV-2 mediates the subversion of the macroautophagy/autophagy pathway remains largely unclear. In this study, we demonstrate that overexpression of the SARS-CoV-2 ORF7a protein activates LC3-II and leads to the accumulation of autophagosomes in multiple cell lines, while knockdown of the viral <i>ORF7a</i> gene via shRNAs targeting <i>ORF7a</i> sgRNA during SARS-CoV-2 infection decreased autophagy levels. …"
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Ozone Chemistry and Photochemistry at the Surface of Icelandic Volcanic Dust: Insights from Elemental Speciation Analysis
منشور في 2021"…Volcanic particulate matter (PM), whether emitted directly as ash or indirectly via suspension of glaciogenic sediments, comprises a large fraction of atmospheric PM in Iceland, a major high-latitude dust source area. …"
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Image_5_TRAPS mutations in Tnfrsf1a decrease the responsiveness to TNFα via reduced cell surface expression of TNFR1.tif
منشور في 2022"…The TNFR1 levels were increased in whole-cell lysates of TRAPS mutant macrophages, whereas the cell surface expression of TNFR1 was significantly decreased in TRAPS mutant macrophages. Taken together, TRAPS mutations did not augment the inflammatory responses to TNFα and LPS; instead, they suppressed the response to TNFα via decreased cell surface expression of TNFR1. …"