Data_Sheet_1_Comparative plasma and urine metabolomics analysis of juvenile and adult canines.PDF by Taibo Wu (14347473)

“…Background and aims<p>The metabolomic profile of a biofluid can be affected by age, and thus provides detailed information about the metabolic alterations in biological processes and reflects the in trinsic rule regulating the growth and developmental processes.…”

Video_3_Therapeutic Effect of Bifidobacterium Administration on Experimental Autoimmune Myasthenia Gravis in Lewis Rats.MP4 by Elena Rinaldi (8155218)

“…Exposure of rat bone marrow-derived dendritic cells to bifidobacteria or lactobacilli strains upregulated toll-like receptor 2 mRNA expression, a key molecule involved in bacterium recognition via lipotheicoic acid. …”

Image_14_Classification of Estrogen Receptor-Positive Breast Cancer Based on Immunogenomic Profiling and Validation at Single-Cell Resolution.TIF by Xianxiong Ma (4276441)

“…Moreover, C2 was associated with a lower tumor mutation burden, a decreased neoantigen load, and fewer CNVs. …”

Kernel Density Plot of Effort Expectancy Scores. by Anis Ben Ghorbal (22521828)

“…<div><p>This paper aimed to explore the impact of disability along with other factors on telehealth usage, examining the degree of ease people feel while using telehealth services in Saudi Arabia. A cross-sectional study collected data from 428 Saudi adult participants via an online survey between October and November 2024. …”

DataSheet_1_Turmeric Is Therapeutic in Vivo on Patient-Derived Colorectal Cancer Xenografts: Inhibition of Growth, Metastasis, and Tumor Recurrence.docx by Mingyue Li (1582399)

“…The application of PDX model was well illustrated here as a good platform to verify the efficacy of multi-targeted herbal extracts.…”

Table_5_Integration of mRNA and miRNA Analysis Reveals the Molecular Mechanism of Cotton Response to Salt Stress.xlsx by Jingjing Zhan (1878034)

“…<p>To identify the regulatory network of known and novel microRNAs (miRNAs) and their targets responding to salt stress, a combined analysis of mRNA libraries, small RNA libraries, and degradome libraries were performed. …”

Image_8_Integration of mRNA and miRNA Analysis Reveals the Molecular Mechanism of Cotton Response to Salt Stress.JPEG by Jingjing Zhan (1878034)

“…<p>To identify the regulatory network of known and novel microRNAs (miRNAs) and their targets responding to salt stress, a combined analysis of mRNA libraries, small RNA libraries, and degradome libraries were performed. …”

Image_3_Optical Control of CD8+ T Cell Metabolism and Effector Functions.pdf by Andrea M. Amitrano (10915356)

“…Strong metabolic suppression in the TME is often associated with impaired T cell recruitment to the tumor site and hyporesponsive effector function via T cell exhaustion. Increasing evidence suggests that mitochondria play a key role in CD8⁺ T cell activation, effector function, and persistence in tumors. …”

Table_3_Discovery of therapeutic targets of quercetin for endometrial carcinoma patients infected with COVID-19 through network pharmacology.xlsx by Kehan Li (413697)

“…Then, regression analyses indicated that 9 prognostic genes (including ANPEP, OAS1, SCGB1A1, HLA‐A, NPPB, FGB, CCL2, TLR4, and SERPINE1) might play important roles in quercetin for treating UCEC/COVID-19. …”

Image1_FGF21-dependent alleviation of cholestasis-induced liver fibrosis by sodium butyrate.TIFF by Jing Yang (13969)

“…NaB administration can thus be a novel nutritional therapy for treating cholestasis via boosting FGF21 signaling and regulating the gut microbiota.…”

Image_1_Transcriptomic Regulation of Muscle Mitochondria and Calcium Signaling by Insulin/IGF-1 Receptors Depends on FoxO Transcription Factors.tif by Gourav Bhardwaj (206574)

“…<p>Insulin and IGF-1, acting through the insulin receptor (IR) and IGF-1 receptor (IGF1R), maintain muscle mass and mitochondrial function, at least part of which occurs via their action to regulate gene expression. Here, we show that while muscle-specific deletion of IR or IGF1R individually results in only modest changes in the muscle transcriptome, combined deletion of IR/IGF1R (MIGIRKO) altered > 3000 genes, including genes involved in mitochondrial dysfunction, fibrosis, cardiac hypertrophy, and pathways related to estrogen receptor, protein kinase A (PKA), and calcium signaling. …”

DataSheet_3_Large plants enhance aboveground biomass in arid natural forest and plantation along differential abiotic and biotic conditions.docx by Bai-Yu Yang (13952523)

“…Although climatic water availability had no direct impact on aboveground biomass in both forests, it indirectly controlled the change of aboveground biomass via species diversity, stand density, and large plants. …”

Data_Sheet_1_Elevated Levels of Arachidonic Acid-Derived Lipids Including Prostaglandins and Endocannabinoids Are Present Throughout ABHD12 Knockout Brains: Novel Insights Into the... by Emma Leishman (781735)

“…<p>Derived from arachidonic acid (AA), the endogenous cannabinoid (eCB) 2-arachidonoyl glycerol (2-AG) is a substrate for α/β hydrolase domain-12 (ABHD12). …”

DataSheet1_Knockout of C1q/tumor necrosis factor-related protein-9 aggravates cardiac fibrosis in diabetic mice by regulating YAP-mediated autophagy.pdf by Shiyan Ruan (18986591)

“…</p>Methods<p>We developed a type 1 diabetes (T1DM) model in CTRP9-KO mice via streptozotocin (STZ) induction to examine cardiac function, histopathology, fibrosis extent, Yes-associated protein (YAP) expression, and the expression of markers for autophagy such LC3-II and p62. …”

Table_1_Yifei Sanjie Formula Treats Chronic Obstructive Pulmonary Disease by Remodeling Pulmonary Microbiota.XLSX by Yueying Wu (747404)

“…Disturbed pulmonary microbiota was discovered to involve an increased relative abundance of Ralstonia and Mycoplasma and a decreased relative abundance of Lactobacillus and Bacteroides in COPD animals. …”

Image_2_Identification and characterization of the LDAP family revealed GhLDAP2_Dt enhances drought tolerance in cotton.jpeg by Yanyan Zhao (211551)

“…In group III, GhLDAP2_At/Dt, especially GhLDAP2_Dt was strongly induced by various abiotic stresses. Decreasing the expression of GhLDAP2_Dt in cotton via virus-induced gene silencing increased the drought sensitivity, and the over-expression of GhLDAP2_Dt led to increased tolerance to mannitol-simulated osmotic stress at the germination stage. …”

Image_5_Integration of mRNA and miRNA Analysis Reveals the Molecular Mechanism of Cotton Response to Salt Stress.JPEG by Jingjing Zhan (1878034)

“…<p>To identify the regulatory network of known and novel microRNAs (miRNAs) and their targets responding to salt stress, a combined analysis of mRNA libraries, small RNA libraries, and degradome libraries were performed. …”

Image3_Posaconazole inhibits the stemness of cancer stem-like cells by inducing autophagy and suppressing the Wnt/β-catenin/survivin signaling pathway in glioblastoma.JPEG by Hua Wang (13530)

“…In summary, this work provides an experimental foundation for exploiting POS as a CSCs-targeting antitumor drug for GBM treatment.…”

Image_6_Classification of Estrogen Receptor-Positive Breast Cancer Based on Immunogenomic Profiling and Validation at Single-Cell Resolution.TIF by Xianxiong Ma (4276441)

“…Moreover, C2 was associated with a lower tumor mutation burden, a decreased neoantigen load, and fewer CNVs. …”

Video_1_GSK3β Interacts With CRMP2 and Notch1 and Controls T-Cell Motility.mp4 by Mobashar Hussain Urf Turabe Fazil (11848967)

“…Here, we report a crucial involvement of GSK3β in T-cell motility. …”