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largest decrease » largest decreases (Expand Search), marked decrease (Expand Search)
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larger decrease » marked decrease (Expand Search)
a decrease » _ decrease (Expand Search), _ decreased (Expand Search), _ decreases (Expand Search)
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25701
Data_Sheet_1_Early Passive Leg Movement Prevents Against the Development of Heart Failure With Preserved Ejection Fraction in Rats.PDF
Published 2021“…In conclusion, treatment of ePLM alleviated high salt diet induced HFpEF by inhibiting fibrosis via suppressing TGF-β1/Smad3 signaling pathway as well as activating Akt/eNOS signaling pathway, implicating treatment of ePLM as a promising novel non-pharmacological approach for HFpEF.…”
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25702
Image_1_Caffeic Acid Phenethyl Ester Ameliorates Calcification by Inhibiting Activation of the AKT/NF-κB/NLRP3 Inflammasome Pathway in Human Aortic Valve Interstitial Cells.tif
Published 2020“…<p>Calcific aortic valve disease (CAVD) occurs via a pathophysiological process that includes inflammation-induced osteoblastic differentiation of aortic valvular interstitial cells (AVICs). …”
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25703
Data Sheet 1_Decoding the hypoxia-exosome-immune triad in OSA: PRCP/UCHL1/BTG2-driven metabolic dysregulation revealed by interpretable machine learning.zip
Published 2025“…OSA is associated with a reproducible transcriptional signature characterized by increased PRCP and UCHL1 expression and decreased BTG2 expression.…”
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25704
Image_1_Skin repair and immunoregulatory effects of myeloid suppressor cells from human cord blood in atopic dermatitis.tiff
Published 2024“…Our findings support the potential of hUCB-MDSCs as a novel treatment strategy for AD.</p>…”
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25705
Image_2_Integration of mRNA and miRNA Analysis Reveals the Molecular Mechanism of Cotton Response to Salt Stress.PNG
Published 2021“…<p>To identify the regulatory network of known and novel microRNAs (miRNAs) and their targets responding to salt stress, a combined analysis of mRNA libraries, small RNA libraries, and degradome libraries were performed. …”
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25706
Video_1_Optical Control of CD8+ T Cell Metabolism and Effector Functions.mp4
Published 2021“…Strong metabolic suppression in the TME is often associated with impaired T cell recruitment to the tumor site and hyporesponsive effector function via T cell exhaustion. Increasing evidence suggests that mitochondria play a key role in CD8<sup>+</sup> T cell activation, effector function, and persistence in tumors. …”
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25707
Probing the Soft and Nanoductile Mechanical Nature of Single and Polycrystalline Organic–Inorganic Hybrid Perovskites for Flexible Functional Devices
Published 2016“…The observed limited brittle fracture behavior is attributed to the transformation of partial edge dislocations to disordered atoms (nanovoid formation). A significant plastic deformation region is observed when nanovoids enlarge and coalesce with adjacent ones, which ultimately leads to crack propagations <i>via</i> ionic-chain breaking. …”
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25708
DataSheet_1_GSK3β Interacts With CRMP2 and Notch1 and Controls T-Cell Motility.pdf
Published 2021“…Here, we report a crucial involvement of GSK3β in T-cell motility. …”
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25709
Table 6_Transcriptional analysis of murine biliary atresia identifies macrophage heterogeneity and subset-specific macrophage functions.xlsx
Published 2025“…Ly6c+ macrophages in murine BA showed increased expression for Hif1a and other genes involved in the cellular response to hypoxia. …”
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25710
Data Sheet 1_Assessment of the effect of social media use on medical students’ academic performance: cross-sectional study from Jordan.pdf
Published 2025“…</p>Methods<p>A cross-sectional study that used structured self-administered online questionnaire to assess the use of social media by a random sample of 429 medical students in Jordan. …”
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25711
Data_Sheet_1_Identification of Biologically Active Ganoderma lucidum Compounds and Synthesis of Improved Derivatives That Confer Anti-cancer Activities in vitro.docx
Published 2019“…We also show for the first time in TNBC/IBC cells that ergosterol peroxide (EP) displays anti-proliferative effects through G1 phase cell cycle arrest, apoptosis induction via caspase 3/7 activation, and PARP cleavage. EP decreased migratory and invasive effects of cancer cells while inhibiting the expression of total AKT1, AKT2, BCL-XL, Cyclin D1 and c-Myc in the tested IBC cells. …”
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25712
Data_Sheet_1_Vacuolar Processing Enzymes Modulating Susceptibility Response to Fusarium oxysporum f. sp. cubense Tropical Race 4 Infections in Banana.pdf
Published 2022“…Furthermore, inhibition of MaVPE activities via caspase-1 inhibitor in the susceptible cultivar reduced tonoplast rupture, decreased lesion formation, and enhanced stress tolerance against FocTR4 infection. …”
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25713
Table_1_GSK3β Interacts With CRMP2 and Notch1 and Controls T-Cell Motility.xlsx
Published 2021“…Here, we report a crucial involvement of GSK3β in T-cell motility. …”
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25714
Image_4_Integration of mRNA and miRNA Analysis Reveals the Molecular Mechanism of Cotton Response to Salt Stress.JPEG
Published 2021“…<p>To identify the regulatory network of known and novel microRNAs (miRNAs) and their targets responding to salt stress, a combined analysis of mRNA libraries, small RNA libraries, and degradome libraries were performed. …”
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25715
Data Sheet 3_Significance of LRFN4 in prognosis and tumor microenvironment of lung adenocarcinoma.xlsx
Published 2025“…</p>Conclusion<p>LRFN4 may serve as a novel prognostic biomarker for LUAD, shows specific overexpression in LUAD and may be a potential therapeutic target for LUAD patients.…”
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25716
Video_1_Blockade of mGluR5 in astrocytes derived from human iPSCs modulates astrocytic function and increases phagocytosis.mp4
Published 2023“…These responses are possible because they sense their surroundings via several receptors, including the metabotropic glutamate receptor 5 (mGluR5). …”
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25717
Longitudinal change of circulating tumour cell count and its relation to prognosis in advanced intrahepatic cholangiocarcinoma patients
Published 2023“…A higher CTC count at diagnosis was correlated with elevated lymph node metastasis (<i>p</i> = 0.005), distant metastasis (<i>p</i> = 0.005) and TNM stage (<i>p</i> = 0.001) but no other characteristics. …”
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25718
Data Sheet 1_Significance of LRFN4 in prognosis and tumor microenvironment of lung adenocarcinoma.xlsx
Published 2025“…</p>Conclusion<p>LRFN4 may serve as a novel prognostic biomarker for LUAD, shows specific overexpression in LUAD and may be a potential therapeutic target for LUAD patients.…”
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25719
Image_1_OX40 Expression in Eosinophils Aggravates OVA-Induced Eosinophilic Gastroenteritis.tif
Published 2022“…</p>Conclusions<p>OX40 may play a critical role in the progress of OVA-induced EGE by promoting the maturation and function of eosinophils via the Traf2/6-related NF-κB signaling pathway.…”
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25720
Image_1_Mechanically-Loaded Breast Cancer Cells Modify Osteocyte Mechanosensitivity by Secreting Factors That Increase Osteocyte Dendrite Formation and Downstream Resorption.TIF
Published 2018“…Though loaded conditioned media decreased MLO cell number, apoptosis was not detected via TUNEL staining, suggesting an inhibition of growth instead. …”