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largest decrease » largest decreases (Expand Search), marked decrease (Expand Search)
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25801
Data Sheet 1_Cellular immune responses of bovine polymorphonuclear neutrophils to Calicophoron daubneyi.pdf
Published 2025“…Likewise, early NETosis was confirmed via nuclear area expansion assays. Bovine neutrophil stimulation with CdAg 100 µg/mL concentration led to a significant increase in oxygen consumption rates (p = 0.0152) and extracellular acidification rates (p = 0.0022), while lower concentrations of CdAg (10 µg/mL) failed to induce neutrophil activation, suggesting a dose dependent response. …”
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25802
Table_1_Dysregulation of the Mitochondrial Proteome Occurs in Mice Lacking Adiponectin Receptor 1.DOCX
Published 2019“…<p>Decreased serum adiponectin levels in type 2 diabetes has been linked to the onset of mitochondrial dysfunction in diabetic complications by impairing AMPK-SIRT1-PGC-1α signaling via impaired adiponectin receptor 1 (AdipoR1) signaling. …”
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25803
Image_7_Integration of mRNA and miRNA Analysis Reveals the Molecular Mechanism of Cotton Response to Salt Stress.JPEG
Published 2021“…<p>To identify the regulatory network of known and novel microRNAs (miRNAs) and their targets responding to salt stress, a combined analysis of mRNA libraries, small RNA libraries, and degradome libraries were performed. …”
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25804
Data_Sheet_1_PRDX2 Protects Against Atherosclerosis by Regulating the Phenotype and Function of the Vascular Smooth Muscle Cell.PDF
Published 2021“…In addition, PRDX2 down-regulation promoted the protein levels of p-p38, p-JNK, and p-ERK, which was confirmed in relevant MAPK inhibitor treatment experiments. Our results suggest a protective role of PRDX2, as a scavenger of ROS, in AS progression through inhibiting the VSMC phenotype alteration and function via MAPK signaling pathway.…”
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25805
Downregulation of endometrial mesenchymal marker SUSD2 causes cell senescence and cell death in endometrial carcinoma cells
Published 2017“…Silencing of <i>SUSD2</i> using siRNA resulted in senescence and cell death of Ishikawa cells <i>via</i> activation of SMAD2/3. These findings suggest that SUSD2 counteracts senescence and cell death and is thus a potential chemotherapeutic target in human endometrial cancer.…”
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25806
Image 3_Interleukin-26 expression in tuberculosis disease and its regulatory effect in macrophage polarization and intracellular elimination of Mycobacterium tuberculosis.jpeg
Published 2024“…Furthermore, our investigations revealed a dose-dependent escalation of reactive oxygen species production, decreased mitochondrial membrane potential, and enhanced autophagy flux activity in THP1 macrophages following IL-26 treatment. …”
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25807
Data_Sheet_1_Cell-Free Supernatant of Odoribacter splanchnicus Isolated From Human Feces Exhibits Anti-colorectal Cancer Activity.pdf
Published 2021“…After GM isolation, cell-free supernatants (CFSs) were prepared from the isolated gut microorganisms to efficiently screen a large amount of the GM for anti-proliferative ability in vitro. …”
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25808
Image_1_Classification of Estrogen Receptor-Positive Breast Cancer Based on Immunogenomic Profiling and Validation at Single-Cell Resolution.TIF
Published 2021“…Moreover, C2 was associated with a lower tumor mutation burden, a decreased neoantigen load, and fewer CNVs. …”
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25809
ROI-Specific paired stability analysis results.
Published 2025“…Reproducibility and stability were assessed via the Concordance Correlation Coefficient (CCC) and pairwise comparisons using paired stability tests. …”
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25810
Data Sheet 5_Transcriptional analysis of murine biliary atresia identifies macrophage heterogeneity and subset-specific macrophage functions.pdf
Published 2025“…Ly6c+ macrophages in murine BA showed increased expression for Hif1a and other genes involved in the cellular response to hypoxia. …”
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25811
The primers used for qRT- PCR.
Published 2015“…<i>adenophorum</i> induces renal cells apoptosis via the activation of mitochondria-mediated apoptosis pathway in renal cells. …”
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25812
Image_12_Classification of Estrogen Receptor-Positive Breast Cancer Based on Immunogenomic Profiling and Validation at Single-Cell Resolution.TIF
Published 2021“…Moreover, C2 was associated with a lower tumor mutation burden, a decreased neoantigen load, and fewer CNVs. …”
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25813
Video_2_GSK3β Interacts With CRMP2 and Notch1 and Controls T-Cell Motility.mp4
Published 2021“…Here, we report a crucial involvement of GSK3β in T-cell motility. …”
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25814
Table1_The therapeutic targets and signaling mechanisms of ondansetron in the treatment of critical illness in the ICU.XLSX
Published 2024“…Ondansetron may reduce excessive inflammatory injury in critical diseases by reducing the formation of NETs via influencing the five targets: TLR8, NFKB1, MAPK14, NE, and MPO. …”
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25815
Table_1_The Contribution of Genetic Variation and Aberrant Methylation of Aryl Hydrocarbon Receptor Signaling Pathway Genes to Rheumatoid Arthritis.doc
Published 2022“…Further, rs11204735 polymorphism was associated with a decreased risk of RA under the dominant model. …”
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25816
Data Sheet 1_Protective effect of Shenqi Wenfei Formula against lipopolysaccharide/cigarette smoke-induced COPD in Rat based on gut microbiota and network pharmacology analysis.zip
Published 2024“…Introduction<p>The incidence of chronic obstructive pulmonary disease (COPD) appears to be increasing and evidence suggests that the intestinal flora may play a causative role in its development. Previous studies found that the Shenqi Wenfei Formula (SQWF) can regulate pyroptosis via the NLRP3/GSDMD pathway, thereby reducing the inflammatory response in the lungs of COPD model rats. …”
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25817
Video_2_Therapeutic Effect of Bifidobacterium Administration on Experimental Autoimmune Myasthenia Gravis in Lewis Rats.MP4
Published 2019“…Exposure of rat bone marrow-derived dendritic cells to bifidobacteria or lactobacilli strains upregulated toll-like receptor 2 mRNA expression, a key molecule involved in bacterium recognition via lipotheicoic acid. …”
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25818
Table_4_Integration of mRNA and miRNA Analysis Reveals the Molecular Mechanism of Cotton Response to Salt Stress.xlsx
Published 2021“…<p>To identify the regulatory network of known and novel microRNAs (miRNAs) and their targets responding to salt stress, a combined analysis of mRNA libraries, small RNA libraries, and degradome libraries were performed. …”
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25819
Data_Sheet_1_Lung Surfactant Lipids Provide Immune Protection Against Haemophilus influenzae Respiratory Infection.pdf
Published 2019“…Decreased levels of surfactant phospholipids have been reported in smokers and patients with COPD. …”
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25820
Image 1_Interleukin-26 expression in tuberculosis disease and its regulatory effect in macrophage polarization and intracellular elimination of Mycobacterium tuberculosis.jpeg
Published 2024“…Furthermore, our investigations revealed a dose-dependent escalation of reactive oxygen species production, decreased mitochondrial membrane potential, and enhanced autophagy flux activity in THP1 macrophages following IL-26 treatment. …”