TAP1-Deficiency Does Not Alter Atherosclerosis Development in <em>Apoe</em>^−/− Mice by Daniel Kolbus (174756)

“…The CD3⁺CD4⁺ T cell fraction was increased in <em>Apoe^−/−Tap1^−/−</em> mice, suggesting a compensation for the decreased CD8⁺ T cell population. …”

Site-Specific <i>N</i>‑Glycoproteomic Analysis Reveals Upregulated Sialylation and Core Fucosylation during Transient Regeneration Loss in Neonatal Mouse Hearts by Jun Li (6494)

“…Notably, the upregulated sialylation was a comprehensive result of increased sialylated glycans with Neu5Gc, with both Neu5Gc and core fucose, and decreased sialylated glycans with Neu5Ac. …”

Analysis of potential targets of 20S-protopanaxadiol on diabetic nephropathy based on network pharmacology, molecular docking, and experimental validation by Chenfei Li (5921768)

“…<p>This study aims to investigate the protective effects and mechanisms of 20S-protopanaxadiol (PPD), a key component derived from ginseng folium, against diabetic nephropathy (DN).…”

DataSheet_1_Mucosal Vaccination Primes NK Cell-Dependent Development of CD8+ T Cells Against Pulmonary Brucella Infection.pdf by Ella Bhagyaraj (588347)

“…<p>Past studies with the live, double-mutant B. abortus (znBAZ) strain resulted in nearly complete protection of mice against pulmonary challenge with wild-type (wt) Brucella via a dominant CD8⁺ T cell response. …”

Data_Sheet_1_Comparative Transcriptome Analysis Uncovers the Regulatory Roles of MicroRNAs Involved in Petal Color Change of Pink-Flowered Strawberry.PDF by Jingyu Yue (12314657)

“…A total of 739 known miRNAs and 964 novel miRNAs were identified via small RNA sequencing, and 639 miRNAs were identified to cleave 2,816 target genes based on the degradome data. …”

Table1_Differential methylation of microRNA encoding genes may contribute to high myopia.DOCX by Joanna Swierkowska (3982061)

“…</p><p>Results: We identified differential methylation of CG dinucleotides in promoter regions of MIR3621, MIR34C, MIR423 (increased methylation level), and MIR1178, MIRLET7A2, MIR885, MIR548I3, MIR6854, MIR675, MIRLET7C, MIR99A (decreased methylation level) genes. …”

Table4_Differential methylation of microRNA encoding genes may contribute to high myopia.XLSX by Joanna Swierkowska (3982061)

“…</p><p>Results: We identified differential methylation of CG dinucleotides in promoter regions of MIR3621, MIR34C, MIR423 (increased methylation level), and MIR1178, MIRLET7A2, MIR885, MIR548I3, MIR6854, MIR675, MIRLET7C, MIR99A (decreased methylation level) genes. …”

Image_6_Dl-3-n-Butylphthalide Reduces Cognitive Impairment Induced by Chronic Cerebral Hypoperfusion Through GDNF/GFRα1/Ret Signaling Preventing Hippocampal Neuron Apoptosis.TIF by Wenxian Li (1577494)

“…<p>Hippocampal neuron death is a key factor in vascular dementia (VD) induced by chronic cerebral hypoperfusion (CCH). …”

Data Sheet 1_Hyaluronan synthase 3 deficiency lowers the incidence of ruptures of abdominal aortic aneurysms by reducing monocyte infiltration.docx by Viola Niemann (22572638)

“…</p>Results<p>Has3 deficiency improved survival in Apoe/Has3-DKO mice via reducing aortic ruptures. This was associated with decreased monocyte infiltration into the vessel wall. …”

Data Sheet 1_Brown adipocyte exosome - derived C22:6 inhibits the IL-1β signaling pathway to alleviate rheumatoid arthritis.pdf by Rui Jiang (264894)

“…This study aimed to investigate the therapeutic potential of exosomes derived from human classical interscapular brown adipocytes (hcBAC-exos) in alleviating symptoms of RA in a mouse model.</p>Methods<p>We established a mouse model of collagen-induced arthritis (CIA) to evaluate the efficacy of hcBAC-exos. …”

Stress-Induced Cell-Cycle Activation in Tip60 Haploinsufficient Adult Cardiomyocytes by Joseph B. Fisher (183954)

“…Aortic-banded Tip60^+/− hearts also exhibited significantly decreased apoptosis.</p> <h3>Conclusions/Significance</h3><p>These findings provide evidence that Tip60 may function in a tumor suppressor pathway(s) to maintain adult cardiomyocytes in replicative senescence.…”

DataSheet4_Platelet pannexin-1 channels modulate neutrophil activation and migration but not the progression of abdominal aortic aneurysm.pdf by Lisa Maria Metz (14721895)

“…<p>Abdominal aortic aneurysm (AAA) is a common disease and highly lethal if untreated. …”

Image_4_Dl-3-n-Butylphthalide Reduces Cognitive Impairment Induced by Chronic Cerebral Hypoperfusion Through GDNF/GFRα1/Ret Signaling Preventing Hippocampal Neuron Apoptosis.TIF by Wenxian Li (1577494)

“…<p>Hippocampal neuron death is a key factor in vascular dementia (VD) induced by chronic cerebral hypoperfusion (CCH). …”

Data_Sheet_2_Comparative Transcriptome Analysis Uncovers the Regulatory Roles of MicroRNAs Involved in Petal Color Change of Pink-Flowered Strawberry.xlsx by Jingyu Yue (12314657)

“…A total of 739 known miRNAs and 964 novel miRNAs were identified via small RNA sequencing, and 639 miRNAs were identified to cleave 2,816 target genes based on the degradome data. …”

Image_1_RA Fibroblast-Like Synoviocytes Derived Extracellular Vesicles Promote Angiogenesis by miRNA-1972 Targeting p53/mTOR Signaling in Vascular Endotheliocyte.tif by Yixiong Chen (129917)

“…Collectively, RA FLSs derived EVs can promote ECs angiogenesis via miR-1972 targeted p53/mTOR signaling, targeting on RA FLSs derived EVs or miR-1972 provides a promising strategy for the treatment of patients with RA.…”

Image-based parameter estimation for epithelial mechanics. by Goshi Ogita (12914958)

“…<p>(A) The structure of the monolayer epithelium. Epithelial cells adhere to each other via cell adhesion molecules such as cadherin (green). …”

12/15-Lipoxygenase-Derived Lipid Metabolites Induce Retinal Endothelial Cell Barrier Dysfunction: Contribution of NADPH Oxidase by Othman, Amira

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Data_Sheet_1_Pathological pericyte expansion and impaired endothelial cell-pericyte communication in endothelial Rbpj deficient brain arteriovenous malformation.pdf by Samantha Selhorst (13718164)

“…Pericytes are necessary for vascular development and homeostasis, with particularly critical roles in the brain, where they are involved in regulating cerebral blood flow and establishing the blood-brain barrier. A role for pericytes during neurovascular disease pathogenesis is less clear—while some studies associate decreased pericyte coverage with select neurovascular diseases, others suggest increased pericyte infiltration in response to hypoxia or traumatic brain injury. …”

Schematic diagram showing Nrf2 induction and consequences during <i>de novo</i> KSHV infection of endothelial cells. by Olsi Gjyshi (641713)

“…This establishes a feed-forward loop where Nrf2 activation induces COX-2 expression, which releases PGE2 and mediates further Nrf2 activation. …”

Image_1_Impediment of Cerebrospinal Fluid Drainage Through Glymphatic System in Glioma.tif by Dan Xu (138152)

“…Our results provide evidence toward a potential new treatment method for glioma in the future.…”