Image1_Long non-coding RNA CASC2 regulates osteoblasts matrix mineralization.tif by Jaime Freitas (1532779)

“…The results indicate that lncRNA CASC2 regulates late osteogenic differentiation and mineralization in hMSC via COMP and BSP. In conclusion, this study suggests that targeting lncRNA CASC2 could be a potential approach for modulating bone mineralization.…”

Table1_Inhibition of Brain GTP Cyclohydrolase I Attenuates 3-Nitropropionic Acid-Induced Striatal Toxicity: Involvement of Mas Receptor/PI3k/Akt/CREB/ BDNF Axis.DOCX by Aya M. Mustafa (11865782)

“…Rats received 3-NP (10 mg/kg/day; i.p.) with or without administration of DAHP (0.5 g/kg/day; i.p.) or wortmannin (WM), a PI3K inhibitor, (15 μg/kg/day; i.v.) for 14 days. …”

Image_6_Exogenous Biological Renal Support Improves Kidney Function in Mice With Rhabdomyolysis-Induced Acute Kidney Injury.TIF by Chao Liu (43092)

“…<p>Background: Rhabdomyolysis (RM) is a clinical syndrome characterized by breakdown of skeletal muscle fibers and release of their contents into the circulation. …”

Data Sheet 3_Global burden of inflammatory bowel disease in children and adolescents, 1990–2021: trends, age-specific patterns and future projections.zip by Hai-Qing Tan (22173514)

“…Introduction<p>Recent epidemiological trends have revealed a marked increase in incidence among children and adolescents. …”

DataSheet_3_Transcriptomic and metabolomic analyses reveal the antifungal mechanism of the compound phenazine-1-carboxamide on Rhizoctonia solani AG1IA.pdf by Ya Zhang (7980)

“…<p>To explore the molecular mechanisms of the antifungal compound phenazine-1-carboxamide (PCN) inhibits Rhizoctonia solani and discover potential targets of action, we performed an integrated analysis of transcriptome and metabolome in R. solani mycelium by whether PCN treating or not. A total of 511 differentially expressed genes (DEGs) were identified between the PCN treatment and control groups. …”

Anti-Obesity Effects of Granulocyte-Colony Stimulating Factor in Otsuka-Long-Evans-Tokushima Fatty Rats by Yonggu Lee (436856)

“…In conclusion, G-CSF treatment reduced body weight and increased energy expenditure in a diabetic model, and enhanced UCP-1 expression and decreased inflammatory cytokine levels may be associated with the effects of G-CSF treatment.…”

Table_1_Global Transcriptomics Uncovers Distinct Contributions From Splicing Regulatory Proteins to the Macrophage Innate Immune Response.xlsx by Allison R. Wagner (11102217)

“…<p>Pathogen sensing via pattern recognition receptors triggers massive reprogramming of macrophage gene expression. …”

Data_Sheet_1_Effect of Sow Intestinal Flora on the Formation of Endometritis.ZIP by Ling Zhang (18071)

“…The results showed a significant difference between endometritis and healthy sows birth canal flora in composition and abundance. …”

DataSheet1_Posaconazole inhibits the stemness of cancer stem-like cells by inducing autophagy and suppressing the Wnt/β-catenin/survivin signaling pathway in glioblastoma.CSV by Hua Wang (13530)

“…In summary, this work provides an experimental foundation for exploiting POS as a CSCs-targeting antitumor drug for GBM treatment.…”

Therapeutic Benefits of Induced Pluripotent Stem Cells in Monocrotaline-Induced Pulmonary Arterial Hypertension by Wei-Chun Huang (312724)

“…<div><p><u>P</u>ulmonary <u>a</u>rterial <u>h</u>ypertension (PAH) is characterized by progressive increases in vascular resistance and the remodeling of pulmonary arteries. …”

CD133/Prominin-1-Mediated Autophagy and Glucose Uptake Beneficial for Hepatoma Cell Survival by Haiyang Chen (380033)

“…<div><p>CD133/Prominin-1 is a pentaspan transmembrane protein that has been frequently used as a biomarker for cancer stem cells, although its biological function is unclear. …”

DataSheet_2_Transcriptomic and metabolomic analyses reveal the antifungal mechanism of the compound phenazine-1-carboxamide on Rhizoctonia solani AG1IA.pdf by Ya Zhang (7980)

“…<p>To explore the molecular mechanisms of the antifungal compound phenazine-1-carboxamide (PCN) inhibits Rhizoctonia solani and discover potential targets of action, we performed an integrated analysis of transcriptome and metabolome in R. solani mycelium by whether PCN treating or not. A total of 511 differentially expressed genes (DEGs) were identified between the PCN treatment and control groups. …”

Image_5_Exogenous Biological Renal Support Improves Kidney Function in Mice With Rhabdomyolysis-Induced Acute Kidney Injury.TIF by Chao Liu (43092)

“…<p>Background: Rhabdomyolysis (RM) is a clinical syndrome characterized by breakdown of skeletal muscle fibers and release of their contents into the circulation. …”

Image_3_Exogenous Biological Renal Support Improves Kidney Function in Mice With Rhabdomyolysis-Induced Acute Kidney Injury.TIF by Chao Liu (43092)

“…<p>Background: Rhabdomyolysis (RM) is a clinical syndrome characterized by breakdown of skeletal muscle fibers and release of their contents into the circulation. …”

CircSCAPER knockdown attenuates IL-1β-induced chondrocyte injury by miR-127-5p/TLR4 axis in osteoarthritis by Yuchang Zhang (13277741)

“…CircSCAPER up-regulation in OA cartilages was discovered to be accompanied by decreased miR-127-5p and increased TLR4. Mechanistically, circSCAPER acted as a sponge for miR-127-5p to positively regulate TLR4 expression in chondrocytes. …”

Table2_Inhibition of Brain GTP Cyclohydrolase I Attenuates 3-Nitropropionic Acid-Induced Striatal Toxicity: Involvement of Mas Receptor/PI3k/Akt/CREB/ BDNF Axis.DOCX by Aya M. Mustafa (11865782)

“…Rats received 3-NP (10 mg/kg/day; i.p.) with or without administration of DAHP (0.5 g/kg/day; i.p.) or wortmannin (WM), a PI3K inhibitor, (15 μg/kg/day; i.v.) for 14 days. …”

Table_1_Network Pharmacology and Absolute Bacterial Quantification-Combined Approach to Explore the Mechanism of Tianqi Pingchan Granule Against 6-OHDA-Induced Parkinson’s Disease... by Zhihua Liu (59139)

“…In vivo studies revealed that class Negativicutes and order Selenomonadales decreased, whereas class Mollicutes, order Enterobacteriales, and Mycoplasmatales increased in fecal samples of PD rats via 16S rRNA sequence analysis. …”

Data_Sheet_1_Early Changes in Nitrate Uptake and Assimilation Under Drought in Relation to Transpiration.pdf by Vít Gloser (9911616)

“…<p>Soil drying combined with nitrogen (N) deficiency poses a grave threat to agricultural crop production. …”

Supplementary file 1_Global burden of inflammatory bowel disease in children and adolescents, 1990–2021: trends, age-specific patterns and future projections.docx by Hai-Qing Tan (22173514)

“…Introduction<p>Recent epidemiological trends have revealed a marked increase in incidence among children and adolescents. …”

DataSheet1_Integrating network pharmacology and experimental verification to explore the mechanism of puerarin against oliguria in acute alcoholism.xls by Mei-Xuan Wan (13929312)

“…<p>Purpose: This study was designed to evaluate the pharmacological mechanisms of puerarin against oliguria in acute alcoholism via network pharmacology analysis combined with experimental verification.…”