Image1_PACAP regulates VPAC1 expression, inflammatory processes and lipid homeostasis in M1- and M2-macrophages.tiff by Roman Witzel (17140549)

“…Therefore, VPAC1 agonists or PACAP may represent a new class of anti-atherogenic therapeutics.</p>…”

Image_1_Brain-Derived Microparticles (BDMPs) Contribute to Neuroinflammation and Lactadherin Reduces BDMP Induced Neuroinflammation and Improves Outcome After Stroke.JPEG by Zhili Chen (2812762)

“…Adult male C57BL/6J mice were subjected to dMCAo and treated via tail vein injection at 3 h after stroke with: (A) +PBS (n = 5/group); (B) +BDMPs (1.5 × 10⁸, n = 6/group); (C) +Lactadherin (400 μg/kg, n = 5/group); (D) +BDMP+Lactadherin (n = 6/group). …”

Image2_PACAP regulates VPAC1 expression, inflammatory processes and lipid homeostasis in M1- and M2-macrophages.tiff by Roman Witzel (17140549)

“…Therefore, VPAC1 agonists or PACAP may represent a new class of anti-atherogenic therapeutics.</p>…”

S1 File - by Yaqin Hu (661123)

“…MiR-204-5p expression was measured via RT‒qPCR. The SIRT1 agonist RSV and a miR-204-5p inhibitor were used to study changes in ER stress (ERS), proliferation, and apoptosis in HEI-OC1 cells. …”

The Foxp3⁺ regulatory T-cell population requires IL-4Rα signaling to control inflammation during helminth infections by Nada Abdel Aziz (3863044)

“…<div><p>Forkhead box P3 (Foxp3⁺) regulatory T (Treg)-cell function is controlled by environmental cues of which cytokine-mediated signaling is a dominant component. In vivo, interleukin-4 (IL-4)-mediated signaling via IL-4 receptor alpha (IL-4Rα) mediates Treg cell transdifferentiation into ex-Foxp3 T helper 2 (Th2) or T helper 17 (Th17) cells. …”

Increased 14-3-3β and γ protein isoform expressions in parasitic eosinophilic meningitis caused by <i>Angiostrongylus cantonensis</i> infection in mice by Hung-Chin Tsai (673178)

“…</p><p>Mice were orally infected with 50 <i>A</i>. <i>cantonensis</i> L3 via an oro-gastric tube and sacrificed every week for 3 consecutive weeks after infection. …”

Effect of photobiomodulation and exercise on early remodeling of the Achilles tendon in streptozotocin-induced diabetic rats by Anderson Rodrigues de Oliveira (6157762)

“…Type 1 diabetes was induced via a single intravenous injection of Streptozotocin at a dose of 40 mg/kg. …”

Comparative analysis on DMS and EE data. by Luca Sesta (17996281)

“…Accuracy is quantified via the Pearson correlation between inferred energies <i>E</i> and independent fitness measurements [<a href="http://www.ploscompbiol.org/article/info:doi/10.1371/journal.pcbi.1011812#pcbi.1011812.ref015" target="_blank">15</a>, <a href="http://www.ploscompbiol.org/article/info:doi/10.1371/journal.pcbi.1011812#pcbi.1011812.ref016" target="_blank">16</a>], as a function of the threshold discrepancy between the two datasets <i>x</i>. …”

Deletion or mutation of <i>FEN1</i> improves fitness of gut-colonizing <i>C</i>. <i>glabrata</i> during caspofungin (CSF) treatment. by Yasmine Hassoun (10761963)

“…<p><b>A.</b> Gut-colonizing <i>fen1</i> mutants survive during CSF therapy better than the isogenic wild type strain. …”

Validation of both the dose and infused patterns of CORT within the circulation of the rat. by Benjamin P. Flynn (11256176)

“…(D) 1 ml of CORT (3.84 μM) was delivered intravenously over 3 hrs in a PULS manner (dashed line) via 20 min (grey bar), hourly CORT infusions at a rate of 1 ml/ hr, whilst the CONS (solid line) rate of 0.33 ml was maintained throughout the experimental period. …”

Crz signaling modulates energy and osmotic homeostasis. by Meet Zandawala (491178)

“…Crz modulates the release of CAPA from Va neurons, which in turn affects chill-coma recovery and desiccation tolerance via its effect on the renal tubules. CAPA is also acting on AKH-producing cells (APCs) and the gut, as shown in [<a href="http://www.plosgenetics.org/article/info:doi/10.1371/journal.pgen.1009425#pgen.1009425.ref061" target="_blank">61</a>]. …”

Data Sheet 1_Mitochondrial damage and IL-1β production in monocytes caused by Neospora caninum infection are mediated by dense granule protein 7 and prohibitins.xlsx by Yu Chen (29959)

“…Interestingly, NcGRA7 formed a complex with the prohibitins PHB1 and PHB2. Using inhibitors of PHB1 or transfecting N. caninum-infected THP-1 cells with PHB1 siRNA significantly decreased IL-1β production, but not TNF-α.…”

Table 1_Mitochondrial damage and IL-1β production in monocytes caused by Neospora caninum infection are mediated by dense granule protein 7 and prohibitins.docx by Yu Chen (29959)

“…Interestingly, NcGRA7 formed a complex with the prohibitins PHB1 and PHB2. Using inhibitors of PHB1 or transfecting N. caninum-infected THP-1 cells with PHB1 siRNA significantly decreased IL-1β production, but not TNF-α.…”

DataSheet1_Functional characterization of SGLT1 using SSM-based electrophysiology: Kinetics of sugar binding and translocation.pdf by Andre Bazzone (3169068)

“…Based on our findings we propose an 11-state kinetic model, introducing a random binding order and intermediate states corresponding to the electrogenic transitions detected via SSME upon substrate binding.…”

Kinetic and Computational Study of Dissociative Substitution and Phosphine Exchange at Tetrahedrally Distorted <i>cis</i>-Pt(SiMePh₂)₂(PMe₂Ph)<sub>... by Ola F. Wendt (1282323)

“…Addition of the leaving ligand causes mass-law retardation compatible with a dissociative process via a three-coordinate transition state or intermediate. …”

Living Polymerization of (<i>o</i>-(Trimethylsilyl)phenyl)acetylene by Molybdenum Imido Alkylidene Complexes by Richard R. Schrock (1295601)

“…<b>2a</b> reacts with (<i>o</i>-(trimethylsilyl)phenyl)acetylene (<i>o</i>-TMSPA) solely via formation of an α-substituted metallacyclobutene intermediate (α addition) that opens to give a single rotamer of a disubstituted alkylidene complex. …”

Notch activation drives apical constriction and epithelial fold. by Hui-Yu Ku (3185502)

“…The clone border is marked by a yellow line (I”) or a white line (J-K). (I) <i>bantam</i> blocks epithelial fold (arrow) via reduced Ena (I’, white) within the clone (16/22). …”

Table_1_Insights into melatonin-induced photosynthetic electron transport under low-temperature stress in cucumber.xlsx by Pei Wu (327833)

“…These results suggest that appropriate MT concentration (100 μmol · L^-1) can improve the photosynthetic performance of PS II and electron transport from primary quinone electron acceptor (Q_A) to secondary quinone electron acceptor (Q_B), promote the balance of energy distribution, strengthen the connectivity of PSI and PSII, improve the electron flow of PSII via Q_A to PC⁺ and P₇₀₀⁺ from reaching PSI by regulating multiple sites of electron transport chain in photosynthesis, and increase the pool size and reduction rates of PSI in low temperature-stressed cucumber plants, All these modifications by MT 100 treatment promoted the photosynthetic electron transfer smoothly, and further restored the cucumber plant growth under low temperature stress. …”

Study group background characteristics. by Zicheng Hu (3825313)

“…Additionally, the <b><i>NSE</i></b> and <b><i>HAD</i></b> groups were augmented by CSF specimens from Milan and Pune to attain a size comparable to the other main groups. When there was a larger number of CSF specimens available for a given group than required for the study, samples were chosen at random from archived collections (e.g., <b><i>CD4-defined</i></b> groups). …”

Image_2_β2-Adrenoceptor Deficiency Results in Increased Calcified Cartilage Thickness and Subchondral Bone Remodeling in Murine Experimental Osteoarthritis.tif by Gundula Rösch (11940632)

“…Purpose<p>Recent studies demonstrated a contribution of adrenoceptors (ARs) to osteoarthritis (OA) pathogenesis. …”