Image_3_Indomethacin Treatment Post-irradiation Improves Mouse Parotid Salivary Gland Function via Modulation of Prostaglandin E2 Signaling.TIFF by Kristy E. Gilman (11163543)

“…Combined, these data suggest a mechanism whereby irradiation-induced PGE₂ signaling to JNK blocks critical steps in saliva secretion manifested by a decrease in the quality (diminished amylase) and quantity (loss of calcium channel activity) of saliva, that can be restored with indomethacin. …”

Image_2_Indomethacin Treatment Post-irradiation Improves Mouse Parotid Salivary Gland Function via Modulation of Prostaglandin E2 Signaling.TIFF by Kristy E. Gilman (11163543)

“…Combined, these data suggest a mechanism whereby irradiation-induced PGE₂ signaling to JNK blocks critical steps in saliva secretion manifested by a decrease in the quality (diminished amylase) and quantity (loss of calcium channel activity) of saliva, that can be restored with indomethacin. …”

Table1_Leishmania major surface components and DKK1 signalling via LRP6 promote migration and longevity of neutrophils in the infection site.docx by Olivia C. Ihedioha (19925886)

Data_Sheet_1_Total Matrix Ca2+ Modulates Ca2+ Efflux via the Ca2+/H+ Exchanger in Cardiac Mitochondria.pdf by Gayathri K. Natarajan (9383882)

“…In Na⁺-free experimental buffer and with Ca²⁺ uptake inhibited, the rate of Ca²⁺ efflux and steady-state free matrix Ca²⁺ [mCa²⁺]_ss increased as the number of administered CaCl₂ boluses increased. ADP and cyclosporine A (CsA), which are known to increase Ca²⁺ buffering while maintaining a constant [mCa²⁺]_ss, decreased the rate of Ca²⁺ efflux via the CHE, with a significantly greater decrease in the presence of ADP. …”

Image 1_Epimedium brevicornu Maxim. extract activates natural killer cells against hepatocellular carcinoma via the cGAS-STING pathway.tif by Lu Liu (171341)

“…</p>Methods<p>The impact of EPE on NK cell activity was assessed via Enzyme-Linked Immunosorbent Assay (ELISA) and flow cytometry. …”

TAL1 associates with the <i>FUBP1</i> promoter via the <i>GATA</i> element to activate <i>FUBP1</i> expression. by Marlene Steiner (6240392)

Schematic of single molecule stochastic binding model. by Michael A. Kelley (13804062)

Association of Hypoxia-Inducible Factor-2 Alpha Gene Polymorphisms with the Risk of Hepatitis B Virus-Related Liver Disease in Guangxi Chinese: A Case-Control Study by Liling Huang (1627294)

“…The rs6715787 CG genotype polymorphism may contribute to a reduced risk of LC in the Guangxi Zhuang Chinese population (OR = 0.152, 95% CI = 0.028–0.807, <i>p</i> = 0.027), as determined via subgroup analysis by ethnicity. …”

Proposed model of miR-199a-5p profibrotic function in lung fibrogenesis. by Christian Lacks Lino Cardenas (282070)

“…In lung fibroblasts, TGFβ binds to TGFβR I (RI) and II (RII) and the resultant complex can be internalized via two distinct endocytic pathways. The clathrin-coated pit pathway (red arrows) increases TGFβ signal transduction leading to the activation of lung fibroblasts and ultimately lung fibrosis whereas the CAV1 lipid raft pathway (green arrows) mediates TGFβ/TGFβR complex degradation, thus decreasing TGFβ signaling and preventing lung fibrosis <a href="http://www.plosgenetics.org/article/info:doi/10.1371/journal.pgen.1003291#pgen.1003291-Rosenbloom1" target="_blank">[73]</a>. …”

Atherosclerotic Oxidized Lipids Affect Formation and Biophysical Properties of Supported Lipid Bilayers and Simulated Membranes by Dane E. Santa (16727929)

“…Oxidized lipids arising from oxidative stress are associated with many serious health conditions, including cardiovascular diseases. For example, KDdiA-PC and KOdiA-PC are two oxidized phosphatidylcholines (oxPC) directly linked to atherosclerosis, which precipitate heart failure, stroke, aneurysms, and chronic kidney disease. …”

Atherosclerotic Oxidized Lipids Affect Formation and Biophysical Properties of Supported Lipid Bilayers and Simulated Membranes by Dane E. Santa (16727929)

“…Oxidized lipids arising from oxidative stress are associated with many serious health conditions, including cardiovascular diseases. For example, KDdiA-PC and KOdiA-PC are two oxidized phosphatidylcholines (oxPC) directly linked to atherosclerosis, which precipitate heart failure, stroke, aneurysms, and chronic kidney disease. …”

Atherosclerotic Oxidized Lipids Affect Formation and Biophysical Properties of Supported Lipid Bilayers and Simulated Membranes by Dane E. Santa (16727929)

“…Oxidized lipids arising from oxidative stress are associated with many serious health conditions, including cardiovascular diseases. For example, KDdiA-PC and KOdiA-PC are two oxidized phosphatidylcholines (oxPC) directly linked to atherosclerosis, which precipitate heart failure, stroke, aneurysms, and chronic kidney disease. …”

Atherosclerotic Oxidized Lipids Affect Formation and Biophysical Properties of Supported Lipid Bilayers and Simulated Membranes by Dane E. Santa (16727929)

“…Oxidized lipids arising from oxidative stress are associated with many serious health conditions, including cardiovascular diseases. For example, KDdiA-PC and KOdiA-PC are two oxidized phosphatidylcholines (oxPC) directly linked to atherosclerosis, which precipitate heart failure, stroke, aneurysms, and chronic kidney disease. …”

Views of the branchial basket flow chambers and cartilage skeleton in a mature, NF 58 larva. by Christopher S. Rose (14420011)

“…The ornate processes decrease in size dorsally and the largest, near the ceratobranchial bases, form a meshwork above each gill slit (small arrows in d). …”

Fig 1 - by Rabia Asghar (18840759)

S1 Dataset - by Rabia Asghar (18840759)

“…While WBC classification was originally rooted in conventional ML, there has been a notable shift toward the use of DL, and particularly convolutional neural networks (CNN), with 54.4% of identified studies (n = 74) including the use of CNNs, and particularly in concurrence with larger datasets and bespoke features e.g., parallel data pre-processing, feature selection, and extraction. …”

Keywords used for iterative database searches. by Rabia Asghar (18840759)

“…While WBC classification was originally rooted in conventional ML, there has been a notable shift toward the use of DL, and particularly convolutional neural networks (CNN), with 54.4% of identified studies (n = 74) including the use of CNNs, and particularly in concurrence with larger datasets and bespoke features e.g., parallel data pre-processing, feature selection, and extraction. …”

Application of the bioinformatics analytical pipeline in a mouse model of brain aging. by Deng Wu (805710)

Fig 7 - by Velma K. Lopez (18510171)

<i>japonicum</i> infection induces MST1 activation. by Jianyang Li (461703)