Discovery and Characterization of the Potent and Selective P2X4 Inhibitor <i>N</i>‑[4-(3-Chlorophenoxy)-3-sulfamoylphenyl]-2-phenylacetamide (BAY-1797) and Structure-Guided Amelior... by Stefan Werner (220458)

“…A structure-guided optimization with respect to decreased pregnane X receptor (PXR) binding was started. …”

<i>E</i>. <i>coli</i> C deep rough LPS mutants show increased susceptibility to chloramphenicol and gentamicin. by Lavisha Parab (14248215)

Overview of the hemagglutination inhibition (HI) assay (top) and illustrative simulation results (bottom). by Janina Linnik (12024904)

Self-Assembly of Atomically Aligned Nanoparticle Superlattices from Pt–Fe₃O₄ Heterodimer Nanoparticles by Shengsong Yang (9930121)

“…Specifically, by using simulations and experiments, we show that heterodimers composed of larger Fe₃O₄ domains decorated with a Pt domain at one vertex can self-assemble into an SL with long-range atomic alignment between the Fe₃O₄ domains of different NPs across the SL. …”

Roadmap of the study protocol and procedures. by Amani Abu-Shaheen (4966288)

“…It is a silicone-based, adjustable device that is applied externally to the bridge of the nose and speeds up clotting by decreasing the temperature and the compressing effect of the device on the nose This study aims to examine the efficacy of the device in attaining hemostasis in goats with anterior nasal bleeding. …”

Stop Nosebleeds device used to stop epistaxis. by Amani Abu-Shaheen (4966288)

“…It is a silicone-based, adjustable device that is applied externally to the bridge of the nose and speeds up clotting by decreasing the temperature and the compressing effect of the device on the nose This study aims to examine the efficacy of the device in attaining hemostasis in goats with anterior nasal bleeding. …”

Characteristics of the study participants. by Michał Wendt (17601180)

“…However, further studies with a larger number of participants and an assessment of long-term effects are necessary.…”

Average bleeding time in both groups. by Amani Abu-Shaheen (4966288)

“…It is a silicone-based, adjustable device that is applied externally to the bridge of the nose and speeds up clotting by decreasing the temperature and the compressing effect of the device on the nose This study aims to examine the efficacy of the device in attaining hemostasis in goats with anterior nasal bleeding. …”

Plasma fatty acid levels by diet type. by Emma Hymel (13281830)

Image3_A novel functional IKBKE variant activating NFAT in a patient with polyarthritis and a remittent fever.jpeg by Saeko Yamada (11899439)

“…Background<p>IKBKE is a negative regulator of T cell activation and one of the key activators of type I interferon (IFN) and NFκB signaling via non-classical pathways. …”

Image1_A novel functional IKBKE variant activating NFAT in a patient with polyarthritis and a remittent fever.jpeg by Saeko Yamada (11899439)

“…Background<p>IKBKE is a negative regulator of T cell activation and one of the key activators of type I interferon (IFN) and NFκB signaling via non-classical pathways. …”

Image2_A novel functional IKBKE variant activating NFAT in a patient with polyarthritis and a remittent fever.jpeg by Saeko Yamada (11899439)

“…Background<p>IKBKE is a negative regulator of T cell activation and one of the key activators of type I interferon (IFN) and NFκB signaling via non-classical pathways. …”

Dorsal-ventral asymmetry of endothelial cell morphology based on more detailed classification. by Daniel Seeler (6451463)

“…Cells wrapping around a larger fraction of the vessel, e.g., D-LR and LR-V, have an area contribution of > 50% but ≤ 75% in the first sector; the majority of their remaining surface area is located in the second sector(s). …”

Identifying the Optimal Pd Ensemble Size in Dilute PdAu Alloy Nanomaterials for Benzaldehyde Hydrogenation by Selina K. Kaiser (16906703)

“…Combining catalyst evaluation, detailed characterization, and mechanistic studies based on density functional theory, we show that Pd single atoms in the Au surface plane (corresponding to samples with 4 atom % Pd in Au) are virtually inactive in this reaction and benzyl alcohol production is optimal over small Pd clusters (corresponding to samples with 10–12 atom % Pd in Au) due to superior benzaldehyde adsorption and transition state stabilization for the C–H bond formation step. For larger Pd ensembles (samples with ≥10 atom % Pd in Au), C–O bond hydrogenolysis occurs, promoting toluene formation and decreasing the selectivity toward benzyl alcohol, in line with a relatively lowered C–O bond cleavage barrier. …”

Electron micrograph of the Langerhans islet of the monkey before and after the hydroxynonenal injections. by Piyakarn Boontem (11663090)

“…Insulin secretory granules of the β-cell (β) are the largest with a clear halo. Glucagon secretory granules of the α-cell (α) lack a clear halo, being a little bit smaller but more electron-dense than insulin granules. …”

Extremely selective neurons. by Alejandro Tlaie (18414707)

Partner choice correlates with fine scale kin structuring in the paper wasp <i>Polistes dominula</i> by Paul John Parsons (7325612)

“…Although we cannot rule out a role for direct kin recognition or natal nest-mate recognition, our data suggest that kin groups may form via a philopatric rule-of-thumb, whereby wasps simply select groups and nesting sites that are nearby. …”

Invasion of cells and cellular infiltration functions overlaid with proteins from the particular comparison for SCC and ADC. by Andrzej Ciereszko (4993370)

Summary heatmap of increases in number of regimes traversed by the nodes. by Jan Stasinski (20371167)

Epigallocatechin Gallate Protects Mice against Methionine–Choline-Deficient-Diet-Induced Nonalcoholic Steatohepatitis by Improving Gut Microbiota To Attenuate Hepatic Injury and Re... by Kaiting Ning (9232988)

“…In our research, we observed that EGCG notably improved MCD-diet-derived gut microbiota dysbiosis, as proved by a distinctively clustered separation from that of the MCD group and by the decrease of the Oxalobacter, Oscillibacter, Coprococcus_1, and Desulfovibrio genera and enrichment of <i>norank_f__Bacteroidales_S24_7_group</i>, Alloprevotella, and Bacteroides. …”