6:2 Chlorinated Polyfluoroalkyl Ether Sulfonate (F-53B) Induces Aging and Parkinson’s Disease-like Disorders in <i>C. elegans</i> at Low Concentrations by Hui Li (32376)

“…Inhibition of antioxidant enzymes and disruption of the normal dopamine cycle via promoting DAT-1 were observed in C. elegans after F-53B exposure, consequently contributing to the increased level of reactive oxygen species (ROS). …”

6:2 Chlorinated Polyfluoroalkyl Ether Sulfonate (F-53B) Induces Aging and Parkinson’s Disease-like Disorders in <i>C. elegans</i> at Low Concentrations by Hui Li (32376)

“…Inhibition of antioxidant enzymes and disruption of the normal dopamine cycle via promoting DAT-1 were observed in C. elegans after F-53B exposure, consequently contributing to the increased level of reactive oxygen species (ROS). …”

6:2 Chlorinated Polyfluoroalkyl Ether Sulfonate (F-53B) Induces Aging and Parkinson’s Disease-like Disorders in <i>C. elegans</i> at Low Concentrations by Hui Li (32376)

“…Inhibition of antioxidant enzymes and disruption of the normal dopamine cycle via promoting DAT-1 were observed in C. elegans after F-53B exposure, consequently contributing to the increased level of reactive oxygen species (ROS). …”

Summary of miRNAs sequencing data quality. by Zhaowen Tan (12283502)

“…After training, total RNA was extracted from the left ventricular myocardium of rats in the SHR-SED group and the BFRT group, miRNAs were sequenced, followed by GO enrichment and KEGG pathway analyses, and the differentially expressed miRNAs were subsequently validated via qRT‒PCR.</p><p>Results</p><p>1) Hemodynamic tests revealed that the blood pressure of SHRs in the BFRT decreased significantly and that the blood pressure level of SHRs in the BFRT decreased more significantly than that of the simple resistance training groups did (P < 0.05). 2) Cardiac function tests revealed that the EF, FS, and MV E/A of SHRs in the BFRT significantly increased, whereas the HR, IVSd, IVSs, LVIDd, LIVDs, LVPWd, LVPWs and LV mass significantly decreased (P < 0.05). 3) Transcriptome sequencing revealed 9 differentially expressed miRNAs in the BFRT group compared with the SHR-SED group (2 miRNAs were significantly upregulated, and 7 miRNAs were significantly downregulated), with P < 0.05 and |log2FoldChange| ≥ 1 used as the criteria for differential significance. …”

The miRNA target genes. by Zhaowen Tan (12283502)

“…After training, total RNA was extracted from the left ventricular myocardium of rats in the SHR-SED group and the BFRT group, miRNAs were sequenced, followed by GO enrichment and KEGG pathway analyses, and the differentially expressed miRNAs were subsequently validated via qRT‒PCR.</p><p>Results</p><p>1) Hemodynamic tests revealed that the blood pressure of SHRs in the BFRT decreased significantly and that the blood pressure level of SHRs in the BFRT decreased more significantly than that of the simple resistance training groups did (P < 0.05). 2) Cardiac function tests revealed that the EF, FS, and MV E/A of SHRs in the BFRT significantly increased, whereas the HR, IVSd, IVSs, LVIDd, LIVDs, LVPWd, LVPWs and LV mass significantly decreased (P < 0.05). 3) Transcriptome sequencing revealed 9 differentially expressed miRNAs in the BFRT group compared with the SHR-SED group (2 miRNAs were significantly upregulated, and 7 miRNAs were significantly downregulated), with P < 0.05 and |log2FoldChange| ≥ 1 used as the criteria for differential significance. …”

Fig 7 - by Kayleigh E. Hood (14334045)

Presentation_1_Trilobatin Protects Against Aβ25–35-Induced Hippocampal HT22 Cells Apoptosis Through Mediating ROS/p38/Caspase 3-Dependent Pathway.zip by Nana Chen (569636)

“…Furthermore, TLB dramatically mitigated cell death after Aβ_25–35 insulted via decreasing the intracellular and mitochondrial ROS overproduction and restoring antioxidant enzyme activities, as well as suppressing apoptosis. …”

Erg251 is the major methyl sterol oxidase controlling drug susceptibility compared to its paralog Erg25. by Xin Zhou (54275)

Let-7a regulates mammosphere formation capacity through Ras/NF-κB and Ras/MAPK/ERK pathway in breast cancer stem cells by Chongwen Xu (736519)

“…In addition, the negative correlation between let-7a and KRas was clearly observed. In vitro, we found that let-7a inhibited mammosphere-forming efficiency and the mammosphere-size via NF-κB and MAPK/ERK pathway, respectively. …”

Effects of D₂O on expression levels of cellular genes involved in “TNF signaling pathway” and “p53 signaling pathway”. by Takeshi Yasuda (1398376)

Predictive Blood Chemistry Parameters for Pansteatitis-Affected Mozambique Tilapia (<i>Oreochromis mossambicus</i>) by John A. Bowden (1813099)

“…In this study, several plasma-based biomarkers accurately classified pansteatitis in Mozambique tilapia (<i>Oreochromis mossambicus</i>) collected from Lake Loskop using a commercially available benchtop blood chemistry analyzer combined with data interpretation via artificial neural network analysis. …”

Presentation_1_Nrf2 Is a Key Regulator on Puerarin Preventing Cardiac Fibrosis and Upregulating Metabolic Enzymes UGT1A1 in Rats.pdf by Shao-Ai Cai (5343128)

“…Treatment with Nrf2 siRNA or brusatol dramatically decreased UGT1A1 expression in puerarin-treated fibroblasts. …”

Data_Sheet_1_The Modulatory Role of CYP3A4 in Dictamnine-Induced Hepatotoxicity.docx by Zhuo-Qing Li (4455073)

“…Dictamnine (DTN), the main alkaloid from DC, possesses a furan ring which was suspected of being responsible for hepatotoxicity via metabolic activation primarily by CYP3A4. …”

Large-Scale Solvent Driven Actuation of Polyelectrolyte Multilayers Based on Modulation of Dynamic Secondary Interactions by Yuanqing Gu (1682098)

“…This unique and recoverable transition in the swelling/shrinking behaviors and the rheological performances of weak polyelectrolyte multilayer film in organic solvents is much larger than changes due to ionic strength or pH, and it enables large scale actuation of a freestanding PEM. …”

Large-Scale Solvent Driven Actuation of Polyelectrolyte Multilayers Based on Modulation of Dynamic Secondary Interactions by Yuanqing Gu (1682098)

“…This unique and recoverable transition in the swelling/shrinking behaviors and the rheological performances of weak polyelectrolyte multilayer film in organic solvents is much larger than changes due to ionic strength or pH, and it enables large scale actuation of a freestanding PEM. …”

Large-Scale Solvent Driven Actuation of Polyelectrolyte Multilayers Based on Modulation of Dynamic Secondary Interactions by Yuanqing Gu (1682098)

“…This unique and recoverable transition in the swelling/shrinking behaviors and the rheological performances of weak polyelectrolyte multilayer film in organic solvents is much larger than changes due to ionic strength or pH, and it enables large scale actuation of a freestanding PEM. …”

Monobenzyltin Complex C1 Induces Apoptosis in MCF-7 Breast Cancer Cells through the Intrinsic Signaling Pathway and through the Targeting of MCF-7-Derived Breast Cancer Stem Cells... by Somayeh Fani (2967933)

Simulations of Droplet Coalescence in Simple Shear Flow by Orest Shardt (1954234)

“…As in experiments, the critical capillary number decreases with increasing droplet size. A second numerical parameter, the interface diffusivity (Péclet number) also influences the conditions for coalescence: coalescence occurs at higher capillary numbers with lower Péclet numbers (higher diffusivity). …”

Simulations of Droplet Coalescence in Simple Shear Flow by Orest Shardt (1954234)

“…As in experiments, the critical capillary number decreases with increasing droplet size. A second numerical parameter, the interface diffusivity (Péclet number) also influences the conditions for coalescence: coalescence occurs at higher capillary numbers with lower Péclet numbers (higher diffusivity). …”

Simulations of Droplet Coalescence in Simple Shear Flow by Orest Shardt (1954234)

“…As in experiments, the critical capillary number decreases with increasing droplet size. A second numerical parameter, the interface diffusivity (Péclet number) also influences the conditions for coalescence: coalescence occurs at higher capillary numbers with lower Péclet numbers (higher diffusivity). …”