Schematic overview of apoptotic pathway regulated by HuD and Msi2. by Naina Gaikwad (20435889)

Spatial distribution of malaria incidence. by Angelina Mageni Lutambi (22097223)

S1 Fig - by Geoff Harley (14593275)

Percentage change in predicted malaria incidence. by Angelina Mageni Lutambi (22097223)

“…<p>Positive % change indicates a decrease in predicted malaria incidence and negative % change indicates an increase in predicted malaria incidence. …”

Generation and characterization of an antagonistic monoclonal antibody against an extracellular domain of mouse DP2 (CRTH2/GPR44) receptors for prostaglandin D₂ by Nanae Nagata (3916574)

“…PGD₂ interacts with 2 types of G protein-coupled receptors, DP1 and DP2/CRTH2 (chemoattractant receptor homologous molecule expressed on T helper type 2 cells)/GPR44 to show a variety of biological effects. DP1 activation leads to Gs-mediated elevation of the intracellular cAMP level, whereas activation of DP2 decreases this level via the Gi pathway; and it also induces G protein-independent, arrestin-mediated cellular responses. …”

Fig 7 - by Geoff Harley (14593275)

Utrophin A mRNA becomes enriched in polysomes in response to PDN treatment. by Pedro Miura (48365)

“…Cell lysates were layered on a continuous sucrose gradient. Absorbance of the gradients was measured at 254 nm from top to bottom via a peristaltic pump and RNA-containing sucrose gradients were fractioned for a total of 12 fractions. …”

Bofu-Tsu-Shosan, an Oriental Herbal Medicine, Exerts a Combinatorial Favorable Metabolic Modulation Including Antihypertensive Effect on a Mouse Model of Human Metabolic Disorders... by Kengo Azushima (468944)

“…Intriguingly, plasma acylated-ghrelin, an active form of orexigenic hormone, and short-term food intake were significantly decreased by single bolus administration of BOF. These results indicate that BOF exerts a combinatorial favorable metabolic modulation including antihypertensive effect, at least partially, via its beneficial effect on adipose tissue function and its appetite-inhibitory property through suppression on the ghrelin system.…”

Fig 5 - by Geoff Harley (14593275)

“…<p>Measurement of markers of inflammation via RT-PCR in WT and PFKFB2 KI kidneys subjected to UUO ± metformin (A-D). mRNA expression of F4.80, TNF-α, Interleukin-1 (IL-1) and Interleukin-6 (IL-6) was significantly reduced with the addition of metformin in wild-type mice (<b>A-D</b> ***p = 0.0001, **p = 0.0016, *p = 0.0230, **p = 0.0008 respectively). …”

Drivers of change in OHI scores from 2012–2016 for a sampling of regions. by Benjamin S. Halpern (180356)

“…<p>Contribution of OHI goals to changes in annual Index scores for the 15 regions with largest increases and decreases in scores and 10 representative regions in between (separated by dark black lines). …”

DMOG treatment affects worm body morphology in a dose-dependent manner. by Megan M. Braun (8201181)

“…<p>A. Midpoint width increases with increasing DMOG dose. …”

SPARC Regulates Transforming Growth Factor Beta Induced (TGFBI) Extracellular Matrix Deposition and Paclitaxel Response in Ovarian Cancer Cells by David A. Tumbarello (680437)

“…Furthermore, ovarian cancer cells have a reduced motility and decreased response to the chemotherapeutic agent paclitaxel when plated on ECM derived from mesothelial cells lacking SPARC compared to control mesothelial-derived ECM. …”

Alpha and beta diversity of gut microbiome. by Xueyan Lin (448667)

Schematic summary of metabolic and transcriptome alterations in MCF-7 breast cancer cells treated with ribitol. by Jason Driver Tucker (14232306)

“…Simultaneously, ribitol treatment decreases the ROS production, not entering into the TCA cycle (Acetyl Co-A not assayed in our study) and no fatty acid synthesis further. …”

A Structural Strategy for Generating Rapid Electron-Transfer Kinetics in Copper(II/I) Systems by Ksenia Krylova (2979108)

“…This is the largest self-exchange rate constant ever reported for a low molecular weight Cu(II/I) system. …”

Experimental timeline: by Christopher Rowan (21499924)

Reductions in the levels of catabolic markers and inflammatory cytokines in OA rats and human chondrocytes. by JooYeon Jhun (3797404)

Model of the control of DgcE activity by the GTPase RdcA and its accessory factor RdcB. by Vanessa Pfiffer (6635057)

“…<p><b>A:</b> At high cellular GTP levels, the RdcA/RdcB complex is predominantly in the GTP-bound form that is unable to interact with the MASE1 domain of DgcE, whose GGDEF domain remains in the monomeric and enzymatically inactive form since the C-terminal EAL domain counteracts dimerization via the PAS₃ region. …”

<i>Hnrnph1</i> Is A Quantitative Trait Gene for Methamphetamine Sensitivity by Neema Yazdani (835533)

“…Transcriptome analysis via mRNA sequencing in the striatum implicated a neurobiological mechanism involving a reduction in mesolimbic innervation and striatal neurotransmission. …”

A Time Series Evaluation of the FAST National Stroke Awareness Campaign in England by Darren Flynn (614507)

“…</p><p>Results</p><p>Before the campaign, emergency admissions (and patients admitted via accident and emergency [A&E]) and thrombolysis activity was increasing significantly over time, whereas emergency admissions via general practitioners (GPs) were decreasing significantly. …”