SSD - a free software for designing multimeric mono-, bi- and trivalent shRNAs by Gabriel José de Carli (8526942)

“…RT-qPCR analysis revealed that our molecule promoted a decrease in more than 50% of the target mRNA, in a dose-dependent manner, when compared to the control group. …”

Impact of lean manufacturing tools on maintenance management at a manufacturing plant in the Western Cape by Gershwin Cornelius (20719184)

“…By proper utilisation of these lean tools, organisations can increase productivity via understanding the lean tools and with corrective actions which do not include hefty machine investments</p><p dir="ltr">The primary research objectives of this study are the following:</p><p dir="ltr">• To determine if a common trend between MTTR and OEE within a manufacturing plant in the Western Cape</p><p dir="ltr">• To determine whether an increase in MTTR results in a decrease in OEE within a manufacturing plant in the Western Cape.…”

Table_1_Allopregnanolone and mood in the peripartum: a longitudinal assessment in healthy women.DOCX by Maria Katharina Grötsch (20299668)

“…Background<p>Allopregnanolone (ALLO), a neuroactive steroid hormone derived from progesterone, can modulate mood via the GABA-A receptor. …”

Supplementary Material for: A comparison of telencephalon composition among chickens, junglefowl, and wild galliforms. by Racicot K. (17982619)

“…Instead, chickens have undergone a mosaic of changes with some regions increasing and others decreasing in size and there are few differences between chickens and junglefowl.…”

Comparison of choroidal thickness in normal eyes and different ocular pathologies in a Brazilian population by Murilo U. Polizelli (10371024)

“…The small sample size in this study was a limitation. Additional research with a larger study population to better understand these findings.…”

Spotlight on Mitochondrial Health: A Trailblazing Fluorescent Tool for Cancer Detection and Surgical Guidance by Wei Zhang (405)

“…The mitochondrial autophagy process of disease-related cells is usually accompanied by a decrease in polarity and pH, and the fluorescence sensing effects caused by these two factors are usually contradictory. …”

Spotlight on Mitochondrial Health: A Trailblazing Fluorescent Tool for Cancer Detection and Surgical Guidance by Wei Zhang (405)

“…The mitochondrial autophagy process of disease-related cells is usually accompanied by a decrease in polarity and pH, and the fluorescence sensing effects caused by these two factors are usually contradictory. …”

Spotlight on Mitochondrial Health: A Trailblazing Fluorescent Tool for Cancer Detection and Surgical Guidance by Wei Zhang (405)

“…The mitochondrial autophagy process of disease-related cells is usually accompanied by a decrease in polarity and pH, and the fluorescence sensing effects caused by these two factors are usually contradictory. …”

Table_1_Inadequate Bioavailability of Intramuscular Epinephrine in a Neonatal Asphyxia Model.DOCX by Sara K. Berkelhamer (4232437)

“…Background<p>Over half a million newborn deaths are attributed to intrapartum related events annually, the majority of which occur in low resource settings. …”

Spotlight on Mitochondrial Health: A Trailblazing Fluorescent Tool for Cancer Detection and Surgical Guidance by Wei Zhang (405)

“…The mitochondrial autophagy process of disease-related cells is usually accompanied by a decrease in polarity and pH, and the fluorescence sensing effects caused by these two factors are usually contradictory. …”

Spotlight on Mitochondrial Health: A Trailblazing Fluorescent Tool for Cancer Detection and Surgical Guidance by Wei Zhang (405)

“…The mitochondrial autophagy process of disease-related cells is usually accompanied by a decrease in polarity and pH, and the fluorescence sensing effects caused by these two factors are usually contradictory. …”

Single Molecule Nanospectroscopy Visualizes Proton-Transfer Processes within a Zeolite Crystal by Zoran Ristanović (1359162)

“…Interestingly, replacing <i>n</i>-heptane with 1-butanol as a solvent led to a reactivity decrease of several orders and shorter survival times of fluorescent products due to the strong chemisorption of 1-butanol onto the Brønsted acid sites. …”

Single Molecule Nanospectroscopy Visualizes Proton-Transfer Processes within a Zeolite Crystal by Zoran Ristanović (1359162)

“…Interestingly, replacing <i>n</i>-heptane with 1-butanol as a solvent led to a reactivity decrease of several orders and shorter survival times of fluorescent products due to the strong chemisorption of 1-butanol onto the Brønsted acid sites. …”

Spotlight on Mitochondrial Health: A Trailblazing Fluorescent Tool for Cancer Detection and Surgical Guidance by Wei Zhang (405)

“…The mitochondrial autophagy process of disease-related cells is usually accompanied by a decrease in polarity and pH, and the fluorescence sensing effects caused by these two factors are usually contradictory. …”

Crystal structure and cytotoxic activities of a bis(pyrrolyl-imine) gold(III) complex by Daniel De Moraes Profirio (2885411)

“…Interaction studies with CT-DNA by fluorescence and competition with ethidium bromide (EB) showed a quenching of the emission band of DNA with a Stern–Volmer quenching constant value of (3.0 ± 0.1) × 10⁴ M⁻¹ and a decrease in fluorescence quenching of EB-DNA system, respectively, confirming that DNA is a possible target for the complex via an intercalative binding, which was confirmed by DNA conformational changes observed with circular dichroism spectroscopy.…”

Development of Potent Immune Modulators Targeting Stimulator of Interferon Genes Receptor by Min Jae Jeon (12274199)

“…</i> Intravenous injection of compounds <b>4a</b> and <b>4c</b> significantly decreased tumor volume in a CT26 murine colorectal carcinoma model, and the immunological memory-derived cancer inhibition was observed in <b>4c</b>-treated mouse models. …”

Sinking towards destiny: High throughput measurement of phytoplankton sinking rates through time-resolved fluorescence plate spectroscopy by Catherine C. Bannon (4487728)

“…We verified the method through experimental analysis of known factors that influence sinking rates, including exponential versus stationary growth phase in species of different cell sizes; <i>Thalassiosira pseudonana</i> CCMP1335, chain-forming <i>Skeletonema marinoi</i> RO5A and <i>Coscinodiscus radiatus</i> CCMP312. We fit decay curves to an algebraic transform of the decrease in fluorescence signal as cells sank away from the fluorometer detector, and then used minimal mechanistic assumptions to extract a sinking rate (m d^-1) using an RStudio script, SinkWORX. …”

A Humanized Mouse Model of HPV-Associated Pathology Driven by E7 Expression by Águeda Buitrago-Pérez (149456)

“…Finally, our findings indicate a decrease of the <em>in vitro</em> capacity of HPV5 E7 to reduce pRb levels <em>in vivo</em>, possibly explaining the phenotypical differences when compared with 16E7-grafts. …”

A Role for PP1/NIPP1 in Steering Migration of Human Cancer Cells by Cristina Martin-Granados (151101)

“…In addition, we identify PP1/NIPP1 as a novel molecular compass that controls directed cell migration via upregulation of Cdc42 signalling and suggest a way by which PP1/NIPP1 may contribute to the migratory properties of cancer cells.…”

Supplementary Material for: Protective effects of Xanthohumol against diabetic nephropathy in a mouse model by Li F. (3206265)

“…Discussion/Conclusion: Xanthohumol could ameliorate DN-related impairments via Nrf2 signaling pathway, which might serve as a promising drug candidate for treatment of DN.…”