miR-19a: An Effective Regulator of SOCS3 and Enhancer of JAK-STAT Signalling by Aideen S. Collins (435532)

“…Functional studies revealed that miR-19a significantly decreased SOCS3 mRNA and protein, while a miR-19a antagomir specifically reversed its inhibitory effect. …”

The Immunology of a Healing Response in Cutaneous Leishmaniasis Treated with Localized Heat or Systemic Antimonial Therapy by Ines Lakhal-Naouar (125773)

“…Immunology of healing, through local or systemic treatments, culminated in similar changes in frequency, quality, and antigen specific responsiveness with immunomodulation possibly via a CD8⁺ T cell dependent mechanism. …”

Supplementary Material for: Continuous Intragastric Dextrose: A Therapeutic Option for Refractory Hypoglycemia in Congenital Hyperinsulinism by Vajravelu M.E. (5607443)

“…<b><i>Methods:</i></b> This was a retrospective cohort of infants with HI treated with IGD from 2009–2017. …”

Mesomorphic properties of cyanobiphenyl dimers with a substituted central malonate unit: overruling effect of fluorination by Marco André Grunwald (5425064)

“…In case of C2-hexyl-substituted dimers, shorter spacers favoured N phases (n = 6–9), while longer spacers favoured SmA phases (n ≥ 9). In addition, decreased clearing temperatures were observed. …”

A possible amplification model of PrP^Sc in prion infected cells. by Keiji Uchiyama (140599)

“…Prion infection stimulates lysosomal degradation of sortilin, thereby impairing the sortilin-mediated trafficking of PrP^C and PrP^Sc to lysosomes. As a result, PrP^C and PrP^Sc are increased at the raft domains and endocytosed via the sortilin-independent pathway, increasing the conversion of PrP^C into PrP^Sc. …”

Image_3_Prenatal Exposure to a Maternal High Fat Diet Increases Hepatic Cholesterol Accumulation in Intrauterine Growth Restricted Rats in Part Through MicroRNA-122 Inhibition of C... by Erin K. Zinkhan (5306672)

“…In vivo inhibition of miR-122 increased hepatic Cyp7a1 protein and decreased hepatic cholesterol. Our findings suggest that IUGR combined with a maternal HFD decreased cholesterol catabolism to bile acids, in part, via miR-122 inhibition of Cyp7a1.…”

Image_1_Prenatal Exposure to a Maternal High Fat Diet Increases Hepatic Cholesterol Accumulation in Intrauterine Growth Restricted Rats in Part Through MicroRNA-122 Inhibition of C... by Erin K. Zinkhan (5306672)

“…In vivo inhibition of miR-122 increased hepatic Cyp7a1 protein and decreased hepatic cholesterol. Our findings suggest that IUGR combined with a maternal HFD decreased cholesterol catabolism to bile acids, in part, via miR-122 inhibition of Cyp7a1.…”

Image_2_Prenatal Exposure to a Maternal High Fat Diet Increases Hepatic Cholesterol Accumulation in Intrauterine Growth Restricted Rats in Part Through MicroRNA-122 Inhibition of C... by Erin K. Zinkhan (5306672)

“…In vivo inhibition of miR-122 increased hepatic Cyp7a1 protein and decreased hepatic cholesterol. Our findings suggest that IUGR combined with a maternal HFD decreased cholesterol catabolism to bile acids, in part, via miR-122 inhibition of Cyp7a1.…”

Table_1_Mineralogy of Deep-Sea Coral Aragonites as a Function of Aragonite Saturation State.DOCX by Gabriela A. Farfan (6063773)

“…Instead, we observe a significant trend of increasing calcite content as a function of both decreasing unit cell parameters as well as decreasing Ω_sw. …”

Altered inflow hemodynamics affects heart development in a side specific manner in the embryonic heart by Alser, Maha W

“…Background: Hemodynamics, forces from the flowing blood in the heart, is a major epigenetic factor for heart development. …”
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Image_2_A Two-Gene-Based Diagnostic Signature for Ruptured Intracranial Aneurysms.TIF by Yuwang Li (11270949)

“…The RT-qPCR further validated that compared with the healthy samples, the expression levels of IL2RB and CCR7 were decreased in ruptured IA samples.</p><p>Conclusions: This study might be helpful for cohorts who have a high risk of ruptured IA for early diagnosis and prevention of the disease.…”

Table_3_A Two-Gene-Based Diagnostic Signature for Ruptured Intracranial Aneurysms.DOCX by Yuwang Li (11270949)

“…The RT-qPCR further validated that compared with the healthy samples, the expression levels of IL2RB and CCR7 were decreased in ruptured IA samples.</p><p>Conclusions: This study might be helpful for cohorts who have a high risk of ruptured IA for early diagnosis and prevention of the disease.…”

The Cysteine-Rich Protein Thimet Oligopeptidase as a Model of the Structural Requirements for S-glutathiolation and Oxidative Oligomerization by Alberto Malvezzi (155925)

“…Previous work on this enzyme revealed that the oxidative oligomerization of EP24.15 is triggered by S-glutathiolation at physiological GSSG levels (10–50 µM) via a mechanism based on thiol-disulfide exchange. …”

Data_Sheet_1_Cognitive Motivation as a Resource for Affective Adjustment and Mental Health.PDF by Alexander Strobel (5898266)

“…</p><p>Conclusion: Based on a large longitudinal data set, the present study expands previous findings and suggests a resource allocation model in which decreasing depressive symptoms lead to a release of capacities benefitting self-regulation directly, and indirectly via cognitive motivation.…”

Food supplementation affects gut microbiota and immunological resistance to parasites in a wild bird species by Sarah Knutie (3609899)

“…Food supplementation increased overall fledging success. Parasitism had a sublethal effects on blood loss, but food supplementation mitigated these effects by increasing parasite resistance via the nestling IgY antibody response.…”

Image_1_A Two-Gene-Based Diagnostic Signature for Ruptured Intracranial Aneurysms.JPEG by Yuwang Li (11270949)

“…The RT-qPCR further validated that compared with the healthy samples, the expression levels of IL2RB and CCR7 were decreased in ruptured IA samples.</p><p>Conclusions: This study might be helpful for cohorts who have a high risk of ruptured IA for early diagnosis and prevention of the disease.…”

Endothelial cell tropism is a determinant of H5N1 pathogenesis in mammalian species by Smanla Tundup (376040)

“…Here, we investigated if the cell tropism of H5N1 virus is a determinant of enhanced virulence in mammalian species. …”

Table_1_A Two-Gene-Based Diagnostic Signature for Ruptured Intracranial Aneurysms.DOCX by Yuwang Li (11270949)

“…The RT-qPCR further validated that compared with the healthy samples, the expression levels of IL2RB and CCR7 were decreased in ruptured IA samples.</p><p>Conclusions: This study might be helpful for cohorts who have a high risk of ruptured IA for early diagnosis and prevention of the disease.…”

Table_2_A Two-Gene-Based Diagnostic Signature for Ruptured Intracranial Aneurysms.DOCX by Yuwang Li (11270949)

“…The RT-qPCR further validated that compared with the healthy samples, the expression levels of IL2RB and CCR7 were decreased in ruptured IA samples.</p><p>Conclusions: This study might be helpful for cohorts who have a high risk of ruptured IA for early diagnosis and prevention of the disease.…”

Data_Sheet_1_Hydrogen Oxidation Influences Glycogen Accumulation in a Verrucomicrobial Methanotroph.pdf by Carlo R. Carere (7254482)

“…Under nitrogen-fixing conditions, removal of hydrogen from the feed-gas resulted in a 14% reduction in observed growth rates and a 144% increase in cellular glycogen content. …”