Image_5_Metformin Modulates T Cell Function and Alleviates Liver Injury Through Bioenergetic Regulation in Viral Hepatitis.tif by Lanman Xu (9549845)

“…Together, our results revealed a protective role and therapeutic potential of metformin against liver injury in acute viral hepatitis via modulating effector T cell activation via regulating the mTORC1 pathway and mitochondrial functions.…”

Image_3_Metformin Modulates T Cell Function and Alleviates Liver Injury Through Bioenergetic Regulation in Viral Hepatitis.tif by Lanman Xu (9549845)

“…Together, our results revealed a protective role and therapeutic potential of metformin against liver injury in acute viral hepatitis via modulating effector T cell activation via regulating the mTORC1 pathway and mitochondrial functions.…”

DataSheet_1_Metformin Modulates T Cell Function and Alleviates Liver Injury Through Bioenergetic Regulation in Viral Hepatitis.docx by Lanman Xu (9549845)

“…Together, our results revealed a protective role and therapeutic potential of metformin against liver injury in acute viral hepatitis via modulating effector T cell activation via regulating the mTORC1 pathway and mitochondrial functions.…”

Combined Experimental and Computational Studies on Carbon−Carbon Reductive Elimination from Bis(hydrocarbyl) Complexes of (PCP)Ir by Rajshekhar Ghosh (1812388)

“…For R/R′ = Ph/Ph, Ph/Me, and Ph/CCPh, we obtain upper limits to the elimination rate; and for R/R′ = CCPh/CCPh, a lower limit. In general, the rates decrease (activation barriers increase) according to the following order: acetylide < vinyl ∼ Me < Ph. …”

Combined Experimental and Computational Studies on Carbon−Carbon Reductive Elimination from Bis(hydrocarbyl) Complexes of (PCP)Ir by Rajshekhar Ghosh (1812388)

“…For R/R′ = Ph/Ph, Ph/Me, and Ph/CCPh, we obtain upper limits to the elimination rate; and for R/R′ = CCPh/CCPh, a lower limit. In general, the rates decrease (activation barriers increase) according to the following order: acetylide < vinyl ∼ Me < Ph. …”

Combined Experimental and Computational Studies on Carbon−Carbon Reductive Elimination from Bis(hydrocarbyl) Complexes of (PCP)Ir by Rajshekhar Ghosh (1812388)

“…For R/R′ = Ph/Ph, Ph/Me, and Ph/CCPh, we obtain upper limits to the elimination rate; and for R/R′ = CCPh/CCPh, a lower limit. In general, the rates decrease (activation barriers increase) according to the following order: acetylide < vinyl ∼ Me < Ph. …”

Combined Experimental and Computational Studies on Carbon−Carbon Reductive Elimination from Bis(hydrocarbyl) Complexes of (PCP)Ir by Rajshekhar Ghosh (1812388)

“…For R/R′ = Ph/Ph, Ph/Me, and Ph/CCPh, we obtain upper limits to the elimination rate; and for R/R′ = CCPh/CCPh, a lower limit. In general, the rates decrease (activation barriers increase) according to the following order: acetylide < vinyl ∼ Me < Ph. …”

Combined Experimental and Computational Studies on Carbon−Carbon Reductive Elimination from Bis(hydrocarbyl) Complexes of (PCP)Ir by Rajshekhar Ghosh (1812388)

“…For R/R′ = Ph/Ph, Ph/Me, and Ph/CCPh, we obtain upper limits to the elimination rate; and for R/R′ = CCPh/CCPh, a lower limit. In general, the rates decrease (activation barriers increase) according to the following order: acetylide < vinyl ∼ Me < Ph. …”

Combined Experimental and Computational Studies on Carbon−Carbon Reductive Elimination from Bis(hydrocarbyl) Complexes of (PCP)Ir by Rajshekhar Ghosh (1812388)

“…For R/R′ = Ph/Ph, Ph/Me, and Ph/CCPh, we obtain upper limits to the elimination rate; and for R/R′ = CCPh/CCPh, a lower limit. In general, the rates decrease (activation barriers increase) according to the following order: acetylide < vinyl ∼ Me < Ph. …”

Combined Experimental and Computational Studies on Carbon−Carbon Reductive Elimination from Bis(hydrocarbyl) Complexes of (PCP)Ir by Rajshekhar Ghosh (1812388)

“…For R/R′ = Ph/Ph, Ph/Me, and Ph/CCPh, we obtain upper limits to the elimination rate; and for R/R′ = CCPh/CCPh, a lower limit. In general, the rates decrease (activation barriers increase) according to the following order: acetylide < vinyl ∼ Me < Ph. …”

Combined Experimental and Computational Studies on Carbon−Carbon Reductive Elimination from Bis(hydrocarbyl) Complexes of (PCP)Ir by Rajshekhar Ghosh (1812388)

“…For R/R′ = Ph/Ph, Ph/Me, and Ph/CCPh, we obtain upper limits to the elimination rate; and for R/R′ = CCPh/CCPh, a lower limit. In general, the rates decrease (activation barriers increase) according to the following order: acetylide < vinyl ∼ Me < Ph. …”

Combined Experimental and Computational Studies on Carbon−Carbon Reductive Elimination from Bis(hydrocarbyl) Complexes of (PCP)Ir by Rajshekhar Ghosh (1812388)

“…For R/R′ = Ph/Ph, Ph/Me, and Ph/CCPh, we obtain upper limits to the elimination rate; and for R/R′ = CCPh/CCPh, a lower limit. In general, the rates decrease (activation barriers increase) according to the following order: acetylide < vinyl ∼ Me < Ph. …”

Viral ORF57 inhibits eIF2α phosphorylation through down-regulation of PKR pathway. by Nishi R. Sharma (4543936)

“…<p>(A) Diagrams of four major stress pathways leading to phosphorylation of eIF2α via different kinases. …”

Table_1_Targeting immunosuppressive Ly6C+ classical monocytes reverses anti-PD-1/CTLA-4 immunotherapy resistance.xlsx by B. Leticia Rodriguez (1953484)

“…Classical Ly6C+ monocytes from ICB resistant tumors had a decrease in both Flt3 and PU.1 expression that prevented differentiation into dendritic cells/macrophages.…”

Presentation_1_Targeting immunosuppressive Ly6C+ classical monocytes reverses anti-PD-1/CTLA-4 immunotherapy resistance.pptx by B. Leticia Rodriguez (1953484)

“…Classical Ly6C+ monocytes from ICB resistant tumors had a decrease in both Flt3 and PU.1 expression that prevented differentiation into dendritic cells/macrophages.…”

Combined Experimental and Computational Studies on Carbon−Carbon Reductive Elimination from Bis(hydrocarbyl) Complexes of (PCP)Ir by Rajshekhar Ghosh (1812388)

“…For R/R′ = Ph/Ph, Ph/Me, and Ph/CCPh, we obtain upper limits to the elimination rate; and for R/R′ = CCPh/CCPh, a lower limit. In general, the rates decrease (activation barriers increase) according to the following order: acetylide < vinyl ∼ Me < Ph. …”

Combined Experimental and Computational Studies on Carbon−Carbon Reductive Elimination from Bis(hydrocarbyl) Complexes of (PCP)Ir by Rajshekhar Ghosh (1812388)

“…For R/R′ = Ph/Ph, Ph/Me, and Ph/CCPh, we obtain upper limits to the elimination rate; and for R/R′ = CCPh/CCPh, a lower limit. In general, the rates decrease (activation barriers increase) according to the following order: acetylide < vinyl ∼ Me < Ph. …”

Effects of under-sampling on analysis of bout duration distributions. by Matt T. Bianchi (236029)

“…<p>The relative frequency histograms of WASO (A1) NREM (A2) and REM sleep (A3) bout durations are shown for a single, randomly selected patient from the control group for comparison with histograms from larger samples (<a href="http://www.plosone.org/article/info:doi/10.1371/journal.pone.0011356#pone-0011356-g001" target="_blank">Figures 1</a> and <a href="http://www.plosone.org/article/info:doi/10.1371/journal.pone.0011356#pone-0011356-g002" target="_blank">2</a>). …”

Transition-Metal Carbonyl Complexes of 2,5-Diferrocenyl-1-phenyl‑1<i>H</i>‑phosphole by Dominique Miesel (1533022)

“…However, the coordination of the dienic system in <b>9</b> results in a significantly decreased electronic communication of the Fc/Fc⁺ termini via the heterocyclic core.…”

Image 1_Emphysema-related mortality rates in the U.S. from 1999 to 2022.pdf by Alexandra Brown (225908)

“…</p>Discussion<p>Emphysema-related deaths in the United States decreased overall between 1999 and 2022, likely a result of a greater emphasis on health education concerning the significant dangers of smoking and policy changes that made cigarettes less accessible and less affordable, and more available access to resources and support networks.…”