Showing 7,681 - 7,700 results of 26,083 for search '(( via ((a decrease) OR (step decrease)) ) OR ( i ((largest decrease) OR (larger decrease)) ))', query time: 1.03s Refine Results
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    Effect of partial Glo-I inhibition by EP on LPS-induced production of TNF-α, collagen-I and α-SMA in HSC. by Marcus Hollenbach (376231)

    Published 2017
    “…Co-treatment of LPS and EP indicated significant dose-dependent reduction of LPS-induced markers of inflammation <b>(A1)</b> and fibrosis <b>(B1, C1)</b>. Presence of LPS and treatment with low-level concentrations of MGO (indicating partial inhibition of Glo-I activity without complete enzyme inhibition) showed significant decrease of LPS-induced release of TNF-α (absence vs. presence of 10mM MGO: 371.8±22.7 vs. 60.9±11.2 pg/ml; p<0.001), collagen-I (10.0±0.3 vs. 1.8±0.5 ng/ml; p<0.001) and α-SMA (68.6±3.6 vs. 43.8±2.2 ng/ml; p<0.001) <b>(A2, B2, C2)</b>. …”
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  8. 7688

    Non-steroidal mineralocorticoid receptor antagonist finerenone inhibits peritoneal fibrosis induced by high-glucose dialysate via regulating enhancer of zeste homolog 2 (EZH2) expr... by Dandan Chen (394689)

    Published 2025
    “…<p>Finerenone, a novel high-selective aldosterone receptor antagonist, exhibits powerful anti-inflammatory and antifibrotic effects in previous researches. …”
  9. 7689

    DataSheet1_Curcumin Ameliorates Cardiac Fibrosis by Regulating Macrophage-Fibroblast Crosstalk via IL18-P-SMAD2/3 Signaling Pathway Inhibition.DOCX by Jing Zhao (21160)

    Published 2022
    “…<p>Ethnopharmacological relevance: Curcumin is a bright yellow chemical produced by plants of the Curcuma longa species. …”
  10. 7690

    Xanthine Oxidase-Derived ROS Upregulate Egr-1 via ERK1/2 in PA Smooth Muscle Cells; Model to Test Impact of Extracellular ROS in Chronic Hypoxia by Tanya Hartney (15297)

    Published 2011
    “…Furthermore, we established in mice a correlation between hypoxic induction of Egr-1 and reduced activity of extracellular superoxide dismutase (EC-SOD), an antioxidant that scavenges extracellular superoxide. …”
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    DataSheet1_Sanqi Oral Solution Mitigates Proteinuria in Rat Passive Heymann Nephritis and Blocks Podocyte Apoptosis via Nrf2/HO-1 Pathway.pdf by Xiaowan Wang (9704207)

    Published 2022
    “…Thus, SQ mitigates podocyte apoptosis and proteinuria in PHN rats via the Nrf2/HO-1 pathway.</p>…”
  14. 7694

    Image_1_Endothelial HSPA12B Exerts Protection Against Sepsis-Induced Severe Cardiomyopathy via Suppression of Adhesion Molecule Expression by miR-126.TIF by Xia Zhang (41398)

    Published 2020
    “…The data suggest that HSPA12B protects against sepsis-induced severe cardiomyopathy via regulating miR-126 expression which targets adhesion molecules, thus decreasing the accumulation of immune cells in the myocardium.…”
  15. 7695

    DataSheet5_Sanqi Oral Solution Mitigates Proteinuria in Rat Passive Heymann Nephritis and Blocks Podocyte Apoptosis via Nrf2/HO-1 Pathway.ZIP by Xiaowan Wang (9704207)

    Published 2021
    “…Thus, SQ mitigates podocyte apoptosis and proteinuria in PHN rats via the Nrf2/HO-1 pathway.</p>…”
  16. 7696

    DataSheet6_Sanqi Oral Solution Mitigates Proteinuria in Rat Passive Heymann Nephritis and Blocks Podocyte Apoptosis via Nrf2/HO-1 Pathway.ZIP by Xiaowan Wang (9704207)

    Published 2021
    “…Thus, SQ mitigates podocyte apoptosis and proteinuria in PHN rats via the Nrf2/HO-1 pathway.</p>…”
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    DataSheet3_Sanqi Oral Solution Mitigates Proteinuria in Rat Passive Heymann Nephritis and Blocks Podocyte Apoptosis via Nrf2/HO-1 Pathway.zip by Xiaowan Wang (9704207)

    Published 2022
    “…Thus, SQ mitigates podocyte apoptosis and proteinuria in PHN rats via the Nrf2/HO-1 pathway.</p>…”
  19. 7699

    DataSheet7_Sanqi Oral Solution Mitigates Proteinuria in Rat Passive Heymann Nephritis and Blocks Podocyte Apoptosis via Nrf2/HO-1 Pathway.ZIP by Xiaowan Wang (9704207)

    Published 2021
    “…Thus, SQ mitigates podocyte apoptosis and proteinuria in PHN rats via the Nrf2/HO-1 pathway.</p>…”
  20. 7700

    DataSheet2_Sanqi Oral Solution Mitigates Proteinuria in Rat Passive Heymann Nephritis and Blocks Podocyte Apoptosis via Nrf2/HO-1 Pathway.ZIP by Xiaowan Wang (9704207)

    Published 2021
    “…Thus, SQ mitigates podocyte apoptosis and proteinuria in PHN rats via the Nrf2/HO-1 pathway.</p>…”