Study characteristics, outcomes and effects. by Amanda L. Seims (16806818)

“…Three of the 13 studies significantly increased children’s physical activity (1 = Moderate to vigorous physical activity, 2 = total volume, <i>P</i><0.05). …”

S1 Dataset - by Yanliqing Song (14492720)

“…The optimal sleep interval for the elderly at night is 6–7.5 hours, and the health benefits are the largest. A sleep duration of < 6 hours at night (OR = 2.25, 95% CI: 1.90 to 2.65) was associated with a high likelihood of depression. …”

Image1_Total flavonoids extracted from Penthorum chinense Pursh mitigates CCl4-induced hepatic fibrosis in rats via inactivation of TLR4-MyD88-mediated NF-κB pathways and regulatio... by Sujuan Wang (1865149)

“…Compared with control animals, CCl₄-treated rats demonstrated obvious liver injury and fibrosis, manifested as increases in gray values, distal diameter of portal vein (DDPV) and a decrease in blood flow velocity (VPV) in the ultrasound analysis; increased biochemical index values (serum levels of ALT, AST, TBIL, and ALP); marked increases in the contents of fibrotic markers (PC III, COL4, LN, HA) and inflammatory factors (serum TNF-α, IL-6, and IL-1β); and significant pathological changes. …”

Image2_Total flavonoids extracted from Penthorum chinense Pursh mitigates CCl4-induced hepatic fibrosis in rats via inactivation of TLR4-MyD88-mediated NF-κB pathways and regulatio... by Sujuan Wang (1865149)

“…Compared with control animals, CCl₄-treated rats demonstrated obvious liver injury and fibrosis, manifested as increases in gray values, distal diameter of portal vein (DDPV) and a decrease in blood flow velocity (VPV) in the ultrasound analysis; increased biochemical index values (serum levels of ALT, AST, TBIL, and ALP); marked increases in the contents of fibrotic markers (PC III, COL4, LN, HA) and inflammatory factors (serum TNF-α, IL-6, and IL-1β); and significant pathological changes. …”

UBR3 affects Shh signaling in mammalian cells by poly-ubiquitinating Kif7. by Tongchao Li (115391)

DataSheet_2_Metabolic Engineering to Improve Docosahexaenoic Acid Production in Marine Protist Aurantiochytrium sp. by Disrupting 2,4-Dienoyl-CoA Reductase.docx by Shitong Liang (13049235)

“…Currently, DHA production costs are high due to fermentation inefficiency; however, improving DHA yield by metabolic engineering in thraustochytrids is one approach to reduce these costs. In this study, a high-yielding (53.97% of total fatty acids) DHA production strain was constructed by disrupting polyunsaturated fatty acid beta-oxidation via knockout of the 2,4-dienyl-CoA reductase (DECR) gene (KO strain) in Aurantiochytrium sp. …”

DataSheet_1_Metabolic Engineering to Improve Docosahexaenoic Acid Production in Marine Protist Aurantiochytrium sp. by Disrupting 2,4-Dienoyl-CoA Reductase.docx by Shitong Liang (13049235)

“…Currently, DHA production costs are high due to fermentation inefficiency; however, improving DHA yield by metabolic engineering in thraustochytrids is one approach to reduce these costs. In this study, a high-yielding (53.97% of total fatty acids) DHA production strain was constructed by disrupting polyunsaturated fatty acid beta-oxidation via knockout of the 2,4-dienyl-CoA reductase (DECR) gene (KO strain) in Aurantiochytrium sp. …”

DataSheet_1_Metabolic Engineering to Improve Docosahexaenoic Acid Production in Marine Protist Aurantiochytrium sp. by Disrupting 2,4-Dienoyl-CoA Reductase.docx by Shitong Liang (13049235)

“…Currently, DHA production costs are high due to fermentation inefficiency; however, improving DHA yield by metabolic engineering in thraustochytrids is one approach to reduce these costs. In this study, a high-yielding (53.97% of total fatty acids) DHA production strain was constructed by disrupting polyunsaturated fatty acid beta-oxidation via knockout of the 2,4-dienyl-CoA reductase (DECR) gene (KO strain) in Aurantiochytrium sp. …”

DataSheet_2_Metabolic Engineering to Improve Docosahexaenoic Acid Production in Marine Protist Aurantiochytrium sp. by Disrupting 2,4-Dienoyl-CoA Reductase.docx by Shitong Liang (13049235)

“…Currently, DHA production costs are high due to fermentation inefficiency; however, improving DHA yield by metabolic engineering in thraustochytrids is one approach to reduce these costs. In this study, a high-yielding (53.97% of total fatty acids) DHA production strain was constructed by disrupting polyunsaturated fatty acid beta-oxidation via knockout of the 2,4-dienyl-CoA reductase (DECR) gene (KO strain) in Aurantiochytrium sp. …”

Neutrophil Superoxide anion production, Heat map for gene expression from neutrophils of CGD patients, and PCA plot for genome-wide gene expression. by Daniel R. Ambruso (12042605)

“…The cells are colored according to expression level relative to row (i.e., relative within gene). Genes that responded to IFN-γ with increased expression are at the bottom and those with decreased expression are at the top. …”

Flexible Optical Waveguides in Heterocyclic Schiff Base Self-Assembled Hydrogen-Bonded Solvates by Yang Ye (175530)

“…Simultaneously adjusting the mechanical and optical properties of crystalline materials remains interesting and challenging. In the present work, a guest molecule was introduced via hydrogen-bonded solvation, which achieved excellent mechanical elasticity and higher fluorescence emission than that of the host heterocyclic Schiff base molecule crystal itself. …”

The model of this work. by Huang Tang (2997894)

Air-Stable Spin-Coated Naphthalocyanine Transistors for Enhanced Chemical Vapor Detection by James E. Royer (1904821)

“…The observed mobility decreases for both sensors are consistent with electron donation trends via hydrogen bonding by basic analytes. …”

Adaptive scaling of contributions from force-field and cryo-EM density data overcomes potential energy barriers without excessive work input. by Christian Blau (4665502)

Complement evasion factor (CEF), a novel immune evasion factor of <i>Streptococcus pyogenes</i> by Haniyeh Aghababa (12020666)

“…This is the first example of a <i>S. pyogenes</i> virulence factor binding to several different target proteins via glycan-dependent interactions.…”

Table_1_Specific Inhibition of CYP4A Alleviates Myocardial Oxidative Stress and Apoptosis Induced by Advanced Glycation End-Products.docx by Rui Wang (52434)

“…The present work aimed to investigate whether CYP4A mediates AGEs-induced myocardial injury. AGEs solution was administered intragastrically to C57BL/6 mice for 60 days, while the specific inhibitor of CYP4A, HET0016, was given from the 47th day via intraperitoneal injection for 2 weeks. …”

The effects of CHRM2 knockdown on osteogenic differentiation and cell proliferation. by Cheng Zhong (573294)

The Prognostic Role of <i>BRAF</i> Mutation in Metastatic Colorectal Cancer Receiving Anti-<i>EGFR</i> Monoclonal Antibodies: A Meta-Analysis by Zi-Xu Yuan (420280)

“…In KRAS WT population, there were even larger PFS benefit (HR 0.29[0.19,0.43]) and larger OS benefit (HR 0.26 [0.20,0.35]) in BRAF WT. …”

data_sheet_1_High-Frequency Repetitive Magnetic Stimulation Enhances the Expression of Brain-Derived Neurotrophic Factor Through Activation of Ca2+–Calmodulin-Dependent Protein Kin... by Ahreum Baek (5179652)

“…Therefore, in this study, we examined the global gene expression patterns depending on different frequencies of repetitive magnetic stimulation (rMS) in both undifferentiated and differentiated Neuro-2a cells to generate a comprehensive view of the biological mechanisms. …”

data_sheet_2_High-Frequency Repetitive Magnetic Stimulation Enhances the Expression of Brain-Derived Neurotrophic Factor Through Activation of Ca2+–Calmodulin-Dependent Protein Kin... by Ahreum Baek (5179652)

“…Therefore, in this study, we examined the global gene expression patterns depending on different frequencies of repetitive magnetic stimulation (rMS) in both undifferentiated and differentiated Neuro-2a cells to generate a comprehensive view of the biological mechanisms. …”