Data_Sheet_1_Determining 5HT7R’s Involvement in Modifying the Antihyperalgesic Effects of Electroacupuncture on Rats With Recurrent Migraine.pdf by Lu Liu (171341)

“…<p>Electroacupuncture (EA) is widely used in clinical practice to relieve migraine pain. 5-HT₇ receptor (5-HT₇R) has been reported to play an excitatory role in neuronal systems and regulate hyperalgesic pain and neurogenic inflammation. 5-HT₇R could influence phosphorylation of protein kinase A (PKA)- or extracellular signal-regulated kinase₁_/₂ (ERK₁_/₂)-mediated signaling pathways, which mediate sensitization of nociceptive neurons via interacting with cyclic adenosine monophosphate (cAMP). …”

Insulin Sensitivity in Adipose and Skeletal Muscle Tissue of Dairy Cows in Response to Dietary Energy Level and 2,4-Thiazolidinedione (TZD) by Afshin Hosseini (827012)

“…The bovine PPARG receptor appears TZD-responsive, with its activation potentially leading to greater adipogenesis and lipogenesis in SAT, while differentially regulating glucose homeostasis and fatty acid oxidation in skeletal muscle. Targeting PPARG via dietary nutraceuticals while avoiding excessive fat deposition might improve insulin sensitivity in dairy cows during times such as the peripartal period when the onset of lactation naturally decreases systemic insulin release and sensitivity in tissues such as AT.…”

Fig 1 - by Sue E. Moore (2932644)

Results of Experiment S1 as a function of Stimulus Type. by İlayda Nazlı (19332772)

GABA catabolic pathway in <i>Drosophila</i> blood-progenitor cells control their GSH levels. by Manisha Goyal (6339704)

Noise and Recurrence Destroy E/I Co-Tuning. by Emmanouil Giannakakis (8415591)

“…</b> An increase in the input noise leads to a reduction in diversity (teal) and, for larger noise intensities, also co-tuning of E/I weights (purple). …”

Ca²⁺ binding mutants expressed and localized correctly. by Mallory C. Shields (4474210)

“…By replacing one aspartate residue deep in the Ca²⁺-binding pocket with a larger, negatively-charged glutamate residue (magenta, larger), the <i>syt^D-E</i> mutation in C₂A blocks Ca²⁺ binding by steric hindrance while maintaining electrostatic repulsion of the presynaptic membrane (large arrows). …”

How Elephant Seals (<i>Mirounga leonina</i>) Adjust Their Fine Scale Horizontal Movement and Diving Behaviour in Relation to Prey Encounter Rate by Yves Le Bras (756623)

“…The southern elephant seal (<i>Mirounga leonina</i>, hereafter SES), the largest phocid, is a major predator of the southern ocean feeding on myctophids and cephalopods. …”

Verification of the effect of various glucose concentrations on cytotoxicity and <i>in vitro</i> wound healing assay in primary cultured rat gingival fibroblasts. by Daisuke Kido (4710143)

“…(B) Effects of various glucose concentrations on <i>in vitro</i> wound healing assay. The relative cell migration area in the 75 mM group significantly decreased from 9 to 36 h compared with that in the 15 mM group. …”

Circulating Tfh1 (cTfh1) cell numbers and PD1 expression are elevated in low-grade B-cell non-Hodgkin’s lymphoma and cTfh gene expression is perturbed in marginal zone lymphoma by Elliot T. Byford (4730568)

“…Lymphoma patients showed increased numbers of cTfh1 and reduced cTfh17 cells due to decreased expression of the subset-defining marker CCR6 in patients. …”

Effects of a person-centred telephone-support in patients with chronic obstructive pulmonary disease and/or chronic heart failure – A randomized controlled trial by Andreas Fors (5706587)

“…</p><p>Results</p><p>At six-month follow-up no difference in the composite score was found between the two study groups (57.6%, n = 68 vs. 46.6%, n = 48; OR = 1.6, 95% CI: 0.9–2.7; P = 0.102) in the intention-to-treat analysis (n = 221); however, significantly more patients in the control group showed a clinically important decrease in GSE (≥ 5 units) (22.9%, n = 27 vs. 9.7%, n = 10; OR = 2.8, 95% CI: 1.3–6.0; P = 0.011). …”

Quantification of number of invasion foci and number of bacteria per infection focus. by Volkan K. Köseoğlu (12055346)

Association analysis for the transplant outcome of clinical CMV (CMV PCR >137 IU/mL) and transcriptomic expression. by Julie M. Steinbrink (14510455)

Phosphoenolpyruvate Carboxykinase, a Key Enzyme That Controls Blood Glucose, Is a Target of Retinoic Acid Receptor-Related Orphan Receptor α by Hiroshi Matsuoka (797627)

“…Transcription is additionally regulated via a cAMP response unit, which includes a cAMP response element and four binding sites for CCAAT/enhancer-binding protein (C/EBP). …”

DataSheet_1_A Testis-Specific Long Noncoding RNA, Start, Is a Regulator of Steroidogenesis in Mouse Leydig Cells.pdf by Kai Otsuka (10507952)

“…The increase in expression of steroidogenic genes in adult Start-KO testes might be caused by a secondary effect via the androgen receptor autocrine pathway or the hypothalamus-pituitary-gonadal axis. …”

DataSheet_1_A Testis-Specific Long Noncoding RNA, Start, Is a Regulator of Steroidogenesis in Mouse Leydig Cells.pdf by Kai Otsuka (10507952)

“…The increase in expression of steroidogenic genes in adult Start-KO testes might be caused by a secondary effect via the androgen receptor autocrine pathway or the hypothalamus-pituitary-gonadal axis. …”

Progression of Osteosarcoma from a Non-Metastatic to a Metastatic Phenotype Is Causally Associated with Activation of an Autocrine and Paracrine uPA Axis by Liliana Endo-Munoz (789643)

“…In addition, in the tumour microenvironment, uPA was expressed and secreted by bone marrow cells (BMC), and OS- and BMC-derived uPA significantly and specifically stimulated migration of metastatic OS cells <i>via</i> uPA-dependent signaling pathways. Silencing of <i>uPAR</i> in metastatic OS cells abrogated the migratory response to uPA <i>in vitro</i> and decreased metastasis <i>in vivo</i>. …”

Antiinflammatory effect of the ethanolic extract of Korean native herb <i>Potentilla rugulosa</i> Nakai in Bisphenol-a-stimulated A549 cells by Yong Geon Choi (16726095)

“…In addition, inhibition of the NF-κB and MAPK signaling pathways by <i>P. rugulosa</i> extract was found to occur via decrease in the transcriptional activity of NF-κB. …”

Clustering and PCA analysis of basal gene expression reveals <i>MITF</i> expression and gene regulation separates melanoma cell lines. by Brian J. Capaldo (800144)

“…Principal component plot of basal expression across the twelve cell lines (C) separates cells according to <i>MITF</i> expression along the first principal component (i.e., decreasing <i>MITF</i> expression going from left to right) and Bliss score across the second principal component.…”

Supplementary file 1_A risk prediction model of spontaneous miscarriage in women with threatened miscarriage: a prospective cohort study.docx by Chee Wai Ku (5722886)

“…Introduction<p>This study aims to develop a holistic risk prediction triage tool for women with threatened miscarriage by integrating clinical, biochemical, and radiological factors. …”