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linear decrease » linear increase (Expand Search)
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linear decrease » linear increase (Expand Search)
marked decrease » marked increase (Expand Search)
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Cyclopropane as an Unsaturation “Effect Isostere”: Lowering the Melting Points in Lipid-like Ionic Liquids
Published 2023“…Inspired by this phenomenon, we herein address the relative effect of the cyclopropanation, both <i>cis</i> and <i>trans</i> configurations, on melting points, packing efficiency, and order of a series of lipid-like ionic liquids via a combination of thermophysical analysis, X-ray crystallography, and computational modeling. …”
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MEDOC: A Fast, Scalable, and Mathematically Exact Algorithm for the Site-Specific Prediction of the Protonation Degree in Large Disordered Proteins
Published 2025“…To address this problem, we developed "multisite extent of deprotonation originating from context" (MEDOC) to determine the degree of protonation of a protein based on the local sequence context of each ionizable residue. …”
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