Data_Sheet_1_Elevated Levels of Arachidonic Acid-Derived Lipids Including Prostaglandins and Endocannabinoids Are Present Throughout ABHD12 Knockout Brains: Novel Insights Into the... by Emma Leishman (781735)

“…Aging and ABHD12 deletion drove widespread changes in the CNS lipidome; however, the effects of ABHD12 deletion were similar between old and young mice, meaning that many alterations in the lipidome precede PHARC-like symptoms. …”

<i>dSERT</i>^<i>16</i> mutants exhibit defects in feeding. by Elizabeth M. Knapp (14149819)

“…(C) Representative images depict visual feeding score used to assay food uptake. (D) Quantification via spectrophotometry of ingested blue dye (n = 13 groups of 10 flies). …”

Estimating germline maintenance. by Mareike Koppik (4489318)

“…However, sociosexual interactions prior to the challenge to the germline decreases offspring quality further in S males but not in N+S and N males (closed symbols). …”

Real-time three-dimensional MRI for the assessment of dynamic carpal instability by Calvin B. Shaw (7406642)

“…Image quality was assessed via blinded scoring by three radiologists and quantitative imaging metrics.…”

Image_1_miR-96 Inhibits SV2C to Promote Depression-Like Behavior and Memory Disorders in Mice.pdf by Lidong Sun (288628)

“…When miR-96 was downregulated or SV2C was overexpressed via intra-cerebroventricular injection with a miR-96 antagonist (miR-96 antagomir) or overexpression of SV2C vector, the Novel Object Recognition Test and sucrose preference index were increased, whereas the escape latency, the number of water maze platform crossings, and the immobility time of the mice were decreased. …”

Bop1 is necessary for brain development in <i>Xenopus laevis</i>. by Corinna Gärtner (13411333)

“…Error bars indicate standard error of the means; *, p ≤ 0.05; ***, p ≤ 0.001; ****, p ≤ 0.0001.…”

Pupil dilation and microsaccades provide complementary insights into the dynamics of arousal and instantaneous attention during effortful listening by Maria Chait (6765644)

“…The speech reception threshold was calculated as the mean SNR of the final four reversals. Participants completed 3 runs in total (the first was used as a practice). …”

Extended data - The SnackerTracker: A novel home-cage monitoring device for measuring food-intake and food-seeking behaviour in mice by Marissa Mueller (20545196)

“…These can be visualised on any connected device, including via the C) mobile app and D) corresponding interface.…”

Image 1_Caffeine on the mind: EEG and cardiovascular signatures of cortical arousal revealed by wearable sensors and machine learning—a pilot study on a male group.jpeg by Shabbir Chowdhury (22246345)

“…EEG was recorded from seven central electrodes (C3, Cz, C4, CP1, CP2, CP5, CP6) using the EMOTIV EPOC Flex system, and heart rate (HR) and blood pressure (BP) were continuously monitored via the Huawei Watch D. Data analysis included power spectral density (PSD) estimation, FOOOF decomposition, and unsupervised k-means clustering.…”

Image_3_CD300b regulates intestinal inflammation and promotes repair in colitis.jpeg by Shmuel Avlas (14825695)

“…Subsequently, current therapeutic approaches target immune-mediated pathways as means for therapeutic intervention and promotion of mucosal healing and repair. …”

Image_1_CD300b regulates intestinal inflammation and promotes repair in colitis.jpeg by Shmuel Avlas (14825695)

“…Subsequently, current therapeutic approaches target immune-mediated pathways as means for therapeutic intervention and promotion of mucosal healing and repair. …”

DataSheet_3_mTORC1 Inhibition Protects Human Regulatory T Cells From Granzyme-B-Induced Apoptosis.docx by Siawosh K. Eskandari (12858206)

“…Here, we assessed the role of inhibiting mechanistic target of rapamycin complex 1 (mTORC1), a recently favored drug target in the transplant field, in regulating human T_reg apoptosis via GrB. Using ex vivo models of human T_reg culture and a humanized mouse model of human skin allotransplantation, we found that by inhibiting mTORC1 using rapamycin, intracytoplasmic expression and functionality of GrB diminished in host T_regs; lowering human T_reg apoptosis by in part decreasing the phosphorylation of S6K and c-Jun. …”

Image_4_CD300b regulates intestinal inflammation and promotes repair in colitis.jpeg by Shmuel Avlas (14825695)

“…Subsequently, current therapeutic approaches target immune-mediated pathways as means for therapeutic intervention and promotion of mucosal healing and repair. …”

Table_1_Music-Enhanced Analgesia and Antiseizure Activities in Animal Models of Pain and Epilepsy: Toward Preclinical Studies Supporting Development of Digital Therapeutics and The... by Cameron S. Metcalf (1997293)

“…<p>Digital therapeutics (software as a medical device) and mobile health (mHealth) technologies offer a means to deliver behavioral, psychosocial, disease self-management and music-based interventions to improve therapy outcomes for chronic diseases, including pain and epilepsy. …”

DataSheet_2_mTORC1 Inhibition Protects Human Regulatory T Cells From Granzyme-B-Induced Apoptosis.docx by Siawosh K. Eskandari (12858206)

“…Here, we assessed the role of inhibiting mechanistic target of rapamycin complex 1 (mTORC1), a recently favored drug target in the transplant field, in regulating human T_reg apoptosis via GrB. Using ex vivo models of human T_reg culture and a humanized mouse model of human skin allotransplantation, we found that by inhibiting mTORC1 using rapamycin, intracytoplasmic expression and functionality of GrB diminished in host T_regs; lowering human T_reg apoptosis by in part decreasing the phosphorylation of S6K and c-Jun. …”

Image_2_CD300b regulates intestinal inflammation and promotes repair in colitis.jpeg by Shmuel Avlas (14825695)

“…Subsequently, current therapeutic approaches target immune-mediated pathways as means for therapeutic intervention and promotion of mucosal healing and repair. …”

DataSheet_1_mTORC1 Inhibition Protects Human Regulatory T Cells From Granzyme-B-Induced Apoptosis.xlsx by Siawosh K. Eskandari (12858206)

“…Here, we assessed the role of inhibiting mechanistic target of rapamycin complex 1 (mTORC1), a recently favored drug target in the transplant field, in regulating human T_reg apoptosis via GrB. Using ex vivo models of human T_reg culture and a humanized mouse model of human skin allotransplantation, we found that by inhibiting mTORC1 using rapamycin, intracytoplasmic expression and functionality of GrB diminished in host T_regs; lowering human T_reg apoptosis by in part decreasing the phosphorylation of S6K and c-Jun. …”

Table_1_Toward a Hybrid Passive BCI for the Modulation of Sustained Attention Using EEG and fNIRS.XLSX by Alexander J. Karran (7824854)

“…The results suggest that providing a means to self-regulate sustained attention has the potential to keep operators engaged over long periods, and moderately increase on-task performance while decreasing on-task error.…”

Data_Sheet_1_Dry Season Transpiration and Soil Water Dynamics in the Central Amazon.docx by Gustavo C. Spanner (6893450)

“…Tree water use was assessed via radial patterns of sap flow in eight dominant canopy trees, each a different species with a range in diameter, height, and wood density. …”

supplementary figure: Osimertinib inhibits the MYLK4-mediated phosphorylation of CDKAL1 to suppress stemness and chemoresistance in rhabdomyosarcoma by Takuto Itano (16830105)

“…The RT‒PCR data are presented as the means ± SDs (n = 3). Statistical significance: ns, p ≥ 0.05. …”