Search alternatives:
largest decrease » largest decreases (Expand Search), marked decrease (Expand Search)
linear decrease » linear increase (Expand Search)
larger decrease » marked decrease (Expand Search)
teer decrease » mean decrease (Expand Search), greater decrease (Expand Search)
largest decrease » largest decreases (Expand Search), marked decrease (Expand Search)
linear decrease » linear increase (Expand Search)
larger decrease » marked decrease (Expand Search)
teer decrease » mean decrease (Expand Search), greater decrease (Expand Search)
-
9201
Image_1_Pharmacokinetic Behavior of Vincristine and Safety Following Intravenous Administration of Vincristine Sulfate Liposome Injection in Chinese Patients With Malignant Lymphom...
Published 2018“…</p><p>Results: In this phase Ia study, a total of eight subjects participated. VCR elimination from the circulation after injection of VSLI was characterized by a significantly increased maximum concentration (C<sub>max</sub>, 86.6 ng/mL) and plasma area under the plasma concentration-time curve from zero to infinity (AUC<sub>0-Inf</sub>, 222.1 ng/mL h), markedly decreased distribution volume (V<sub>z</sub>, 224.1 L) and plasma clearance (CL, 8.9 L/h) compared to lower C<sub>max</sub> (26.6 ng/mL) and AUC<sub>0-Inf</sub> (95.1 ng/mL h), larger V<sub>z</sub> (688.8 L) and CL (22.1 L/h) for VSI. …”
-
9202
Image_6_Pharmacokinetic Behavior of Vincristine and Safety Following Intravenous Administration of Vincristine Sulfate Liposome Injection in Chinese Patients With Malignant Lymphom...
Published 2018“…</p><p>Results: In this phase Ia study, a total of eight subjects participated. VCR elimination from the circulation after injection of VSLI was characterized by a significantly increased maximum concentration (C<sub>max</sub>, 86.6 ng/mL) and plasma area under the plasma concentration-time curve from zero to infinity (AUC<sub>0-Inf</sub>, 222.1 ng/mL h), markedly decreased distribution volume (V<sub>z</sub>, 224.1 L) and plasma clearance (CL, 8.9 L/h) compared to lower C<sub>max</sub> (26.6 ng/mL) and AUC<sub>0-Inf</sub> (95.1 ng/mL h), larger V<sub>z</sub> (688.8 L) and CL (22.1 L/h) for VSI. …”
-
9203
Image_7_Pharmacokinetic Behavior of Vincristine and Safety Following Intravenous Administration of Vincristine Sulfate Liposome Injection in Chinese Patients With Malignant Lymphom...
Published 2018“…</p><p>Results: In this phase Ia study, a total of eight subjects participated. VCR elimination from the circulation after injection of VSLI was characterized by a significantly increased maximum concentration (C<sub>max</sub>, 86.6 ng/mL) and plasma area under the plasma concentration-time curve from zero to infinity (AUC<sub>0-Inf</sub>, 222.1 ng/mL h), markedly decreased distribution volume (V<sub>z</sub>, 224.1 L) and plasma clearance (CL, 8.9 L/h) compared to lower C<sub>max</sub> (26.6 ng/mL) and AUC<sub>0-Inf</sub> (95.1 ng/mL h), larger V<sub>z</sub> (688.8 L) and CL (22.1 L/h) for VSI. …”
-
9204
Image_3_Pharmacokinetic Behavior of Vincristine and Safety Following Intravenous Administration of Vincristine Sulfate Liposome Injection in Chinese Patients With Malignant Lymphom...
Published 2018“…</p><p>Results: In this phase Ia study, a total of eight subjects participated. VCR elimination from the circulation after injection of VSLI was characterized by a significantly increased maximum concentration (C<sub>max</sub>, 86.6 ng/mL) and plasma area under the plasma concentration-time curve from zero to infinity (AUC<sub>0-Inf</sub>, 222.1 ng/mL h), markedly decreased distribution volume (V<sub>z</sub>, 224.1 L) and plasma clearance (CL, 8.9 L/h) compared to lower C<sub>max</sub> (26.6 ng/mL) and AUC<sub>0-Inf</sub> (95.1 ng/mL h), larger V<sub>z</sub> (688.8 L) and CL (22.1 L/h) for VSI. …”
-
9205
Image_2_Pharmacokinetic Behavior of Vincristine and Safety Following Intravenous Administration of Vincristine Sulfate Liposome Injection in Chinese Patients With Malignant Lymphom...
Published 2018“…</p><p>Results: In this phase Ia study, a total of eight subjects participated. VCR elimination from the circulation after injection of VSLI was characterized by a significantly increased maximum concentration (C<sub>max</sub>, 86.6 ng/mL) and plasma area under the plasma concentration-time curve from zero to infinity (AUC<sub>0-Inf</sub>, 222.1 ng/mL h), markedly decreased distribution volume (V<sub>z</sub>, 224.1 L) and plasma clearance (CL, 8.9 L/h) compared to lower C<sub>max</sub> (26.6 ng/mL) and AUC<sub>0-Inf</sub> (95.1 ng/mL h), larger V<sub>z</sub> (688.8 L) and CL (22.1 L/h) for VSI. …”
-
9206
Image_4_Pharmacokinetic Behavior of Vincristine and Safety Following Intravenous Administration of Vincristine Sulfate Liposome Injection in Chinese Patients With Malignant Lymphom...
Published 2018“…</p><p>Results: In this phase Ia study, a total of eight subjects participated. VCR elimination from the circulation after injection of VSLI was characterized by a significantly increased maximum concentration (C<sub>max</sub>, 86.6 ng/mL) and plasma area under the plasma concentration-time curve from zero to infinity (AUC<sub>0-Inf</sub>, 222.1 ng/mL h), markedly decreased distribution volume (V<sub>z</sub>, 224.1 L) and plasma clearance (CL, 8.9 L/h) compared to lower C<sub>max</sub> (26.6 ng/mL) and AUC<sub>0-Inf</sub> (95.1 ng/mL h), larger V<sub>z</sub> (688.8 L) and CL (22.1 L/h) for VSI. …”
-
9207
Effects of low-dose rate γ-irradiation combined with simulated microgravity on markers of oxidative stress, DNA methylation potential, and remodeling in the mouse heart
Published 2017“…However, further research is needed with larger numbers of animals for a more robust statistical power to fully characterize the early and late effects of simulated microgravity combined with exposure to low-dose rate ionizing radiation on the heart.…”
-
9208
Equilibrium model predictions for the pattern formation time and readout error.
Published 2018“…<p>(A) The early nuclear cycles have a short interphase <i>T</i><sub>full</sub> and even shorter steady state periods <i>T</i> when the average transcription rate is neither increasing after, nor decreasing before, transcription shut-off during mitosis. …”
-
9209
Data_Sheet_1_PET image enhancement using artificial intelligence for better characterization of epilepsy lesions.docx
Published 2022“…We trained a ResNet on 80% of this dataset (10% used for validation) to learn the mapping between S-SQ and GT-HQ PET, outputting a predicted HQ (P-HQ) PET. …”
-
9210
Table_2_Characterization of Non-hormone Expressing Endocrine Cells in Fetal and Infant Human Pancreas.DOCX
Published 2019“…</p><p>Objective: To establish the replicative frequency and transcriptional identity of CPHN cells, extending our observation on CPHN cell frequency to a larger cohort of fetal and infant pancreas.</p><p>Design, Setting, and Participants: 8 fetal, 19 infant autopsy pancreata were evaluated for CPHN cell frequency; 12 fetal, 24 infant/child pancreata were evaluated for CPHN replication and identity.…”
-
9211
Image_4_Characterization of Non-hormone Expressing Endocrine Cells in Fetal and Infant Human Pancreas.jpg
Published 2019“…</p><p>Objective: To establish the replicative frequency and transcriptional identity of CPHN cells, extending our observation on CPHN cell frequency to a larger cohort of fetal and infant pancreas.</p><p>Design, Setting, and Participants: 8 fetal, 19 infant autopsy pancreata were evaluated for CPHN cell frequency; 12 fetal, 24 infant/child pancreata were evaluated for CPHN replication and identity.…”
-
9212
Image_7_Characterization of Non-hormone Expressing Endocrine Cells in Fetal and Infant Human Pancreas.jpg
Published 2019“…</p><p>Objective: To establish the replicative frequency and transcriptional identity of CPHN cells, extending our observation on CPHN cell frequency to a larger cohort of fetal and infant pancreas.</p><p>Design, Setting, and Participants: 8 fetal, 19 infant autopsy pancreata were evaluated for CPHN cell frequency; 12 fetal, 24 infant/child pancreata were evaluated for CPHN replication and identity.…”
-
9213
Table_3_Characterization of Non-hormone Expressing Endocrine Cells in Fetal and Infant Human Pancreas.DOCX
Published 2019“…</p><p>Objective: To establish the replicative frequency and transcriptional identity of CPHN cells, extending our observation on CPHN cell frequency to a larger cohort of fetal and infant pancreas.</p><p>Design, Setting, and Participants: 8 fetal, 19 infant autopsy pancreata were evaluated for CPHN cell frequency; 12 fetal, 24 infant/child pancreata were evaluated for CPHN replication and identity.…”
-
9214
Image_1_Characterization of Non-hormone Expressing Endocrine Cells in Fetal and Infant Human Pancreas.jpg
Published 2019“…</p><p>Objective: To establish the replicative frequency and transcriptional identity of CPHN cells, extending our observation on CPHN cell frequency to a larger cohort of fetal and infant pancreas.</p><p>Design, Setting, and Participants: 8 fetal, 19 infant autopsy pancreata were evaluated for CPHN cell frequency; 12 fetal, 24 infant/child pancreata were evaluated for CPHN replication and identity.…”
-
9215
Image_5_Characterization of Non-hormone Expressing Endocrine Cells in Fetal and Infant Human Pancreas.jpg
Published 2019“…</p><p>Objective: To establish the replicative frequency and transcriptional identity of CPHN cells, extending our observation on CPHN cell frequency to a larger cohort of fetal and infant pancreas.</p><p>Design, Setting, and Participants: 8 fetal, 19 infant autopsy pancreata were evaluated for CPHN cell frequency; 12 fetal, 24 infant/child pancreata were evaluated for CPHN replication and identity.…”
-
9216
Table_1_Characterization of Non-hormone Expressing Endocrine Cells in Fetal and Infant Human Pancreas.DOCX
Published 2019“…</p><p>Objective: To establish the replicative frequency and transcriptional identity of CPHN cells, extending our observation on CPHN cell frequency to a larger cohort of fetal and infant pancreas.</p><p>Design, Setting, and Participants: 8 fetal, 19 infant autopsy pancreata were evaluated for CPHN cell frequency; 12 fetal, 24 infant/child pancreata were evaluated for CPHN replication and identity.…”
-
9217
Table_4_Characterization of Non-hormone Expressing Endocrine Cells in Fetal and Infant Human Pancreas.DOCX
Published 2019“…</p><p>Objective: To establish the replicative frequency and transcriptional identity of CPHN cells, extending our observation on CPHN cell frequency to a larger cohort of fetal and infant pancreas.</p><p>Design, Setting, and Participants: 8 fetal, 19 infant autopsy pancreata were evaluated for CPHN cell frequency; 12 fetal, 24 infant/child pancreata were evaluated for CPHN replication and identity.…”
-
9218
Image_6_Characterization of Non-hormone Expressing Endocrine Cells in Fetal and Infant Human Pancreas.jpg
Published 2019“…</p><p>Objective: To establish the replicative frequency and transcriptional identity of CPHN cells, extending our observation on CPHN cell frequency to a larger cohort of fetal and infant pancreas.</p><p>Design, Setting, and Participants: 8 fetal, 19 infant autopsy pancreata were evaluated for CPHN cell frequency; 12 fetal, 24 infant/child pancreata were evaluated for CPHN replication and identity.…”
-
9219
Image_2_Characterization of Non-hormone Expressing Endocrine Cells in Fetal and Infant Human Pancreas.jpg
Published 2019“…</p><p>Objective: To establish the replicative frequency and transcriptional identity of CPHN cells, extending our observation on CPHN cell frequency to a larger cohort of fetal and infant pancreas.</p><p>Design, Setting, and Participants: 8 fetal, 19 infant autopsy pancreata were evaluated for CPHN cell frequency; 12 fetal, 24 infant/child pancreata were evaluated for CPHN replication and identity.…”
-
9220
Image_8_Characterization of Non-hormone Expressing Endocrine Cells in Fetal and Infant Human Pancreas.jpg
Published 2019“…</p><p>Objective: To establish the replicative frequency and transcriptional identity of CPHN cells, extending our observation on CPHN cell frequency to a larger cohort of fetal and infant pancreas.</p><p>Design, Setting, and Participants: 8 fetal, 19 infant autopsy pancreata were evaluated for CPHN cell frequency; 12 fetal, 24 infant/child pancreata were evaluated for CPHN replication and identity.…”