Elementary Steps in Olefin Metathesis: Nickelacyclobutanes via Cycloaddition to Nickel Carbenes by Samantha K. Cormier (16872384)

“…Computations pinpoint a decreased energy barrier to cycloreversion, relative to reductive elimination or β-H elimination, as the core requirement to achieve metathesis. …”

(A) Shape of the osteotomies during the 3-step MIPS drilling procedure. by Marsel Ganeyev (21453399)

The decreased permeability caused by phospholipid content in the membrane could drive the emergence of other functions in the protocells. by Wentao Ma (326530)

(A) Procedural steps for minimally invasive Ponto surgery (MIPS). The MIPS procedure involves the following steps: (i) A circular incision is created at the selected site via a 4-... by Marsel Ganeyev (21453399)

Effective contact rate over time for the different modelling scenarios considered: fixed, continuously increasing, continuously decreasing and with a step-decrease. by Joshua Looker (21390948)

“…<p>Effective contact rate over time for the different modelling scenarios considered: fixed, continuously increasing, continuously decreasing and with a step-decrease.</p>…”

Disturbance of coherent behaviour leads to a decrease in information transfer. by Hannah Zoller (19688084)

Femur length anomalies tend to decrease with later phenology (greater day of year of adulthood anomaly) regardless of elevation or species’ seasonal timing. by César R. Nufio (11646271)

Heart failure decreases adipocyte progenitors with impaired differentiation capacity toward mature adipocytes by Oto Inoue (21373982)

“…With respect to the mechanism of impaired APC function in HF, we identified that augmented sympathetic nerve activity partially mediated the decrease in APC counts via unilateral adipose tissue denervation (ATD). …”

Algorithm operation steps. by Junyan Wang (4738518)

“…To improve model accuracy further, we introduce the SE attention mechanism that adaptively adjusts the weights of feature channels to enhance the discriminative ability of insulator defect features. …”

Overview of study procedures. by Matthew G. Vinson (22593374)

“…VIDEO and CONTROL were associated with a similar rise in intent to decrease OTC NSAID use (1.92 (SD: 4.41) vs. 1.36 (SD: 3.46), p = 0.150) and a similar decrease in NSAIDs exposure (−32.8% in VIDEO and −36.5% in CONTROL, p = 0.520) 4 weeks post-intervention. …”

Flow diagram illustrating the sequence of procedures executed during one time step defined as tick, each of which represents one week. by Alexandra M. Campbell (3284094)

Subjects:

Simulation Results Plot of the SBW System Response: (a) Step response curve of the SBW system; (b) Sine response curve of the SBW system; (c) Steady state error curve of the SBW sy... by Honglei Pang (22693724)

Simulation Results Plot of the EMB System Response: (a) Step response curve of the EMB system; (b) Sine response curve of the EMB system; (c) Steady state error curve of the EMB sy... by Honglei Pang (22693724)

Hypoxia Rewires Histone Methylation in Glioblastoma Cells via Enzyme Reprogramming Despite Disruption of One-Carbon Metabolism by Hui Tang (226667)

“…Despite this blockade in one-carbon metabolism, global histone methylation patterns were not uniformly suppressed. Instead, we observed site-specific changes driven by altered expression of methyltransferases and demethylases, particularly decreased KMT1F (H3K9 methylation) and KMT2B (H3K4 methylation) and increased KDM2A (H3K36 demethylation), KDM3A (H3K9 demethylation), and KMT5A/SETD8 (H4K20 monomethylation). …”

Hypoxia Rewires Histone Methylation in Glioblastoma Cells via Enzyme Reprogramming Despite Disruption of One-Carbon Metabolism by Hui Tang (226667)

“…Despite this blockade in one-carbon metabolism, global histone methylation patterns were not uniformly suppressed. Instead, we observed site-specific changes driven by altered expression of methyltransferases and demethylases, particularly decreased KMT1F (H3K9 methylation) and KMT2B (H3K4 methylation) and increased KDM2A (H3K36 demethylation), KDM3A (H3K9 demethylation), and KMT5A/SETD8 (H4K20 monomethylation). …”

Hypoxia Rewires Histone Methylation in Glioblastoma Cells via Enzyme Reprogramming Despite Disruption of One-Carbon Metabolism by Hui Tang (226667)

“…Despite this blockade in one-carbon metabolism, global histone methylation patterns were not uniformly suppressed. Instead, we observed site-specific changes driven by altered expression of methyltransferases and demethylases, particularly decreased KMT1F (H3K9 methylation) and KMT2B (H3K4 methylation) and increased KDM2A (H3K36 demethylation), KDM3A (H3K9 demethylation), and KMT5A/SETD8 (H4K20 monomethylation). …”

A lysine-restricted diet ameliorates obesity via enrichment of Parabacteroides goldsteinii and 1,4-methylimidazoleacetic acid by Chengzhi Chen (19567437)

“…Mechanistically, we show that MIAA inhibits the expression of the demethylase FTO, leading to increased m6A modifications on Slc2a4 mRNA via the reader protein YTHDC1. …”

A Novel Type of PSMA-Targeting Ligands via β‑Branched Aromatic α‑Amino Acid Modification, Bearing Enhanced Tumor Targeting and Reduced Renal Toxicity by Zong-Xiao Liu (22177765)

“…We designed and synthesized a novel type of PSMA radioligand incorporating (2<i>S</i>, 3<i>R</i>) β-branched aromatic α-amino acids within the linker segment of its structure. …”

A Novel Type of PSMA-Targeting Ligands via β‑Branched Aromatic α‑Amino Acid Modification, Bearing Enhanced Tumor Targeting and Reduced Renal Toxicity by Zong-Xiao Liu (22177765)

“…We designed and synthesized a novel type of PSMA radioligand incorporating (2<i>S</i>, 3<i>R</i>) β-branched aromatic α-amino acids within the linker segment of its structure. …”

LBM-based approach using synchronous transformation with a time step of 0.43s, PNGM-based method using asynchronous transformation with a 5s time step, VGA using explicit scheme wi... by Mouad Klai (20818364)