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via large » a large (Expand Search)
large decrease » larger decrease (Expand Search), marked decrease (Expand Search), large increases (Expand Search)
nn decrease » a decrease (Expand Search), mean decrease (Expand Search), gy decreased (Expand Search)
_ decrease » _ decreased (Expand Search), _ decreasing (Expand Search)
via large » a large (Expand Search)
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A lysine-restricted diet ameliorates obesity via enrichment of Parabacteroides goldsteinii and 1,4-methylimidazoleacetic acid
Published 2025“…Metabolomics revealed that P. goldsteinii increases 1,4-methylimidazoleacetic acid (MIAA), a metabolite linked to decreased body weight in animal models. Mechanistically, we show that MIAA inhibits the expression of the demethylase FTO, leading to increased m6A modifications on Slc2a4 mRNA via the reader protein YTHDC1. …”
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