Showing 1 - 20 results of 2,604 for search '(( via large decrease ) OR ((( m6a ((step decrease) OR (we decrease)) ) OR ( _ large decrease ))))', query time: 0.62s Refine Results
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    A lysine-restricted diet ameliorates obesity via enrichment of Parabacteroides goldsteinii and 1,4-methylimidazoleacetic acid by Chengzhi Chen (19567437)

    Published 2025
    “…Metabolomics revealed that P. goldsteinii increases 1,4-methylimidazoleacetic acid (MIAA), a metabolite linked to decreased body weight in animal models. Mechanistically, we show that MIAA inhibits the expression of the demethylase FTO, leading to increased m6A modifications on Slc2a4 mRNA via the reader protein YTHDC1. …”
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