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large decrease » marked decrease (Expand Search), large increases (Expand Search), large degree (Expand Search)
age increased » rate increased (Expand Search), use increased (Expand Search), large increases (Expand Search)
non decrease » nn decrease (Expand Search), point decrease (Expand Search), note decreased (Expand Search)
a decrease » _ decrease (Expand Search), _ decreased (Expand Search), _ decreases (Expand Search)
via large » a large (Expand Search)
a age » _ age (Expand Search), g age (Expand Search), 9 age (Expand Search)
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Data_Sheet_1_COX5A Plays a Vital Role in Memory Impairment Associated With Brain Aging via the BDNF/ERK1/2 Signaling Pathway.docx
Published 2020“…In vitro studies supported that COX5A affected neuronal growth via BDNF. In summary, this study was the first to show that COX5A in the hippocampus plays a vital role in aging-related cognitive deterioration via BDNF/ERK1/2 regulation, and suggested that COX5A may be a potential target for anti-senescence drugs.…”
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The results of the brain age monotonicity analysis for interval 3.
Published 2024“…With the 1000FCP dataset, the values β<sub>0</sub> = 24.2, β<sub>1</sub> = 0.58, and the Spearman correlation of 0.795 indicate a gradual increase and moderate monotonicity. For SRPBS, β<sub>0</sub> = 3.11, β<sub>1</sub> = 0.788, and the Spearman correlation of 0.853 demonstrates monotonicity in the number of subjects classified as aged with increasing age. …”
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Decrease in the burst onset latency of the recruited neurons leads to pruning of long delay connections.
Published 2021“…<p>A: Burst onset latency between the parent and the recruited neurons decreases during recruitment. …”
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Given a linear growth trajectory, increasing survival increases optimal maturation age and size.
Published 2020“…<p>As annual survival <i>s</i> increases, the growth curve is unchanged, but the iso-fitness curves become less steep and the age-0 intercepts increase (see <a href="http://www.plosone.org/article/info:doi/10.1371/journal.pone.0228990#pone.0228990.g008" target="_blank">Fig 8</a>), so optimal age and length increase along the growth curve. …”
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