GXM decreases the trans-endothelial electrical resistance (TEER) and transmigration of <i>C</i>. <i>neoformans</i> through HBECs in a blood brain barrier (BBB) model. by Hiu Ham Lee (15374677)

Data_Sheet_1_m7G Methyltransferase METTL1 Promotes Post-ischemic Angiogenesis via Promoting VEGFA mRNA Translation.docx by Yongchao Zhao (2450917)

“…However, the role of N7-methylguanosine (m7G), particularly m7G in mRNA, on post-ischemic angiogenesis remains largely unknown. Here, we identified that methyltransferase like 1 (METTL1) was a critical candidate responsible for a global decrease of m7G within mRNA from the ischemic tissues. …”

Cyclopropane as an Unsaturation “Effect Isostere”: Lowering the Melting Points in Lipid-like Ionic Liquids by Richard A. O’Brien (1538818)

“…Inspired by this phenomenon, we herein address the relative effect of the cyclopropanation, both <i>cis</i> and <i>trans</i> configurations, on melting points, packing efficiency, and order of a series of lipid-like ionic liquids via a combination of thermophysical analysis, X-ray crystallography, and computational modeling. …”

Data Sheet 1_Patient engagement in radiation oncology: a large retrospective study of survey response dynamics.docx by Bailey A. Loving (20573882)

“…</p>Methods<p>This retrospective study analyzed data from radiation oncology patients at a large multi-site single-institution center from May 2021 to January 2024. …”

CRISPR <i>kcnk5b</i> KO strategy, targeting efficiency of endogenous locus and Kcnk5b mutants. by Xiaowen Jiang (8291814)

The ORF7a protein of SARS-CoV-2 initiates autophagy and limits autophagosome-lysosome fusion via degradation of SNAP29 to promote virus replication by Peili Hou (4737219)

“…However, how SARS-CoV-2 mediates the subversion of the macroautophagy/autophagy pathway remains largely unclear. In this study, we demonstrate that overexpression of the SARS-CoV-2 ORF7a protein activates LC3-II and leads to the accumulation of autophagosomes in multiple cell lines, while knockdown of the viral <i>ORF7a</i> gene via shRNAs targeting <i>ORF7a</i> sgRNA during SARS-CoV-2 infection decreased autophagy levels. …”

Total viable immune cells and macrophages decrease acutely while neutrophils and macrophage increase at day 30 in parotid glands after 5Gy IR. by Jordan A. Gunning (18143970)

Relish checks JNK activation in the progenitors via tak1 function to prevent precocious differentiation. by Parvathy Ramesh (12571120)

“…<p>(A-B) Levels of <i>puc</i> transcripts upon progenitor-specific Rel downregulation (A) (N = 3, P-value <0.0083), (B) Rel overexpression causes a decrease in <i>puc</i> transcripts (N = 3, P-value: 0.001). …”

Femur length anomalies tend to decrease with later phenology (greater day of year of adulthood anomaly) regardless of elevation or species’ seasonal timing. by César R. Nufio (11646271)

Prevalence and patterns of helmet use among motorized two-wheelers: findings from a large observational study in an Indian metropolis by Gautham Melur Sukumar (14341571)

“…Helmet use and other information were collected by trained Field Data Collectors <i>via</i> hand-held tablet devices and the KoBo collect application, following a globally used checklist. …”

M⁶A-mediated up-regulation of LncRNA LIFR-AS1 enhances the progression of pancreatic cancer via miRNA-150-5p/ VEGFA/Akt signaling by Jian-Qing Chen (8271900)

“…However, the exact role of m⁶A induced LIFR-AS1 in pancreatic cancer (PC) and its potential molecular mechanisms remain largely unknown. …”

Decrease in accelerometer assessed physical activity during the first-year post-myocardial infarction: a prospective cohort study by Amanda Lönn (11583010)

“…Secondly, to explore associations between changes in physical activity variables with blood pressure and lipid levels.</p> <p>A longitudinal study in 2017-2023. Physical activity variables were assessed <i>via</i> accelerometers at two- and twelve months post-MI. …”

VEEV CPD shows decreased phosphorylation of capsid and replication is not sensitive to loss of PKCδ. by Brian D. Carey (6092747)

Image_9_Comprehensive Characterization of Cachexia-Inducing Factors in Diffuse Large B-Cell Lymphoma Reveals a Molecular Subtype and a Prognosis-Related Signature.TIFF by Zhixing Kuang (10809975)

“…Background<p>Cachexia is defined as an involuntary decrease in body weight, which can increase the risk of death in cancer patients and reduce the quality of life. …”

Image_3_Comprehensive Characterization of Cachexia-Inducing Factors in Diffuse Large B-Cell Lymphoma Reveals a Molecular Subtype and a Prognosis-Related Signature.TIFF by Zhixing Kuang (10809975)

“…Background<p>Cachexia is defined as an involuntary decrease in body weight, which can increase the risk of death in cancer patients and reduce the quality of life. …”

Image_5_Comprehensive Characterization of Cachexia-Inducing Factors in Diffuse Large B-Cell Lymphoma Reveals a Molecular Subtype and a Prognosis-Related Signature.TIF by Zhixing Kuang (10809975)

“…Background<p>Cachexia is defined as an involuntary decrease in body weight, which can increase the risk of death in cancer patients and reduce the quality of life. …”

Image_10_Comprehensive Characterization of Cachexia-Inducing Factors in Diffuse Large B-Cell Lymphoma Reveals a Molecular Subtype and a Prognosis-Related Signature.TIFF by Zhixing Kuang (10809975)

“…Background<p>Cachexia is defined as an involuntary decrease in body weight, which can increase the risk of death in cancer patients and reduce the quality of life. …”

Image_2_Comprehensive Characterization of Cachexia-Inducing Factors in Diffuse Large B-Cell Lymphoma Reveals a Molecular Subtype and a Prognosis-Related Signature.TIFF by Zhixing Kuang (10809975)

“…Background<p>Cachexia is defined as an involuntary decrease in body weight, which can increase the risk of death in cancer patients and reduce the quality of life. …”

Image_1_Comprehensive Characterization of Cachexia-Inducing Factors in Diffuse Large B-Cell Lymphoma Reveals a Molecular Subtype and a Prognosis-Related Signature.TIFF by Zhixing Kuang (10809975)

“…Background<p>Cachexia is defined as an involuntary decrease in body weight, which can increase the risk of death in cancer patients and reduce the quality of life. …”

Image_7_Comprehensive Characterization of Cachexia-Inducing Factors in Diffuse Large B-Cell Lymphoma Reveals a Molecular Subtype and a Prognosis-Related Signature.TIFF by Zhixing Kuang (10809975)

“…Background<p>Cachexia is defined as an involuntary decrease in body weight, which can increase the risk of death in cancer patients and reduce the quality of life. …”