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marked decrease » marked increase (Expand Search)
large decrease » larger decrease (Expand Search), large increases (Expand Search), large degree (Expand Search)
b decrease » _ decrease (Expand Search), a decrease (Expand Search), b1 decreased (Expand Search)
weight b » weight _ (Expand Search), weight a (Expand Search), weight c (Expand Search)
marked decrease » marked increase (Expand Search)
large decrease » larger decrease (Expand Search), large increases (Expand Search), large degree (Expand Search)
b decrease » _ decrease (Expand Search), a decrease (Expand Search), b1 decreased (Expand Search)
weight b » weight _ (Expand Search), weight a (Expand Search), weight c (Expand Search)
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<b>Effect of Marked Weight Loss on Adipose Tissue Biology in People with Obesity and Type 2 Diabetes</b>
Published 2025“…</p><p dir="ltr"><b>Results: </b>Weight loss: <a href="" target="_blank">i) </a><a href="" target="_blank">decreased adipose tissue </a>expression of genes related to extracellular matrix remodeling; ii) decreased adipose tissue expression of SERPINE 1 which encodes plasminogen activator inhibitor-1 (PAI-1); iii) did not decrease adipose tissue immune cell content or expression of genes involved in inflammation; iv) decreased adipose tissue ceramide content; v) decreased plasma <a href="" target="_blank">PAI-1 </a>and leptin concentrations and increased plasma high-molecular weight (HMW) adiponectin; and vi) decreased plasma small extracellular vesicle (sEV) concentration and the sEV content of microRNAs proposed to inhibit insulin action, and completely reversed the inhibitory effect of plasma sEVs on insulin signaling in myotubes.…”
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<b>Effects of marked weight loss induced by gastric bypass surgery or low-calorie diet alone on postprandial glucose disposal in type 2 diabetes</b>
Published 2025“…<a href="" target="_blank"> Total postprandial glucose appearance rate was lower after compared with before weight loss in both the BDT and RYGB groups because of a decrease in endogenous glucose production, without a difference between groups. …”
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related to Fig 5. (A) the total number of eggs in the livers did not differ between BL/6 and Gsdmd-/- mice.
Published 2025“…<p>Number of eggs were microscopically counted in pieces of weighted liver from BL/6 and Gsdmd-/- mice (B) Total CD45+ populations were decreased in the Gsdmd-/- livers. …”