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point decrease » point increase (Expand Search)
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Mitochondrial dysfunction is driven by decreased mitochondrial dynamics.
Published 2014“…<p>(A) Sensitivity analysis averaged along the time course for the mitochondrial species in the model by varying the mitochondrial-related kinetic rate constant parameters. …”
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In the absence of chloride, two-fold decrease in [Na<sup>+</sup>]<sub>e</sub> shifted GLT-1a E<sub>rev</sub> by −28 mV at both low and high glutamate concentrations.
Published 2015“…<b>(B)</b> Representative data show total membrane current, the time courses of [Na<sup>+</sup>]<sub>e</sub>, [Glu<sup>-</sup>]<sub>e</sub>, and [DHK]<sub>e</sub> at the top, and HP voltage ramps (–100 to +20 mV) at the bottom. Arrow head points to simultaneous decrease in [Glu<sup>-</sup>]<sub>e</sub> and [Na<sup>+</sup>]<sub>e</sub>, which affects the current. …”
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OCA alone markedly decreases and combined with Gemcitabine or Cisplatin abrogates growth of iCCA xenografts.
Published 2019“…After 4 weeks, when the tumor size was approximately 100 mm<sup>3</sup> (T<sub>0</sub>) mice were treated with OCA (0.03% w/w, 30 mg/kg) alone or combined with Cisplatin (2.4 mg/Kg in 100 μl) or Gemcitabine (1.05 mg/Kg in 100 μl) for 5 additional weeks. a) Results are expressed as percent increase in tumor volume at different time points. …”
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Structural details for each point mutation studied by X-ray crystallography in this study.
Published 2023Subjects: -
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PowerPoint Slides for: Patiromer Decreases Serum Potassium and Phosphate Levels in Patients on Hemodialysis
Published 2016“…<p><b><i>Background:</i></b> Persistent hyperkalemia (serum potassium (K) ≥5.5 mEq/l) is a common condition in hemodialysis (HD) patients, is associated with increased mortality, and treatment options are limited. …”
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Significant decrease of SMAD4 protein in DBA iPSCs.
Published 2015“…A) Slight decrease of mRNA level of <i>SMAD4</i> in the DBA iPSCs with <i>RPS19</i> or <i>RPL5</i> mutations. …”
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Claudin V is decreased following infection with Mtb.
Published 2024“…<p>Immunofluorescent staining of guinea pig brain tissue for DAPI (blue) and claudin V (cyan) in vessels was performed. Representative images of the frontal cortex (A–D), cerebral nuclei (F–I), brain stem (K–N), thalamus (P–S), and hippocampus (U–X) 15 days post-infection are shown. …”
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<i>Kdm6a</i> knockdown causes a female-specific decrease in <i>Rhox6</i> and <i>9</i> expression in ES cells.
Published 2013“…<p>(A) Quantitative RT-PCR after <i>Kdm6a</i> knockdown in female PGK12.1 ES cells shows a 75% and a 52% decrease in <i>Kdm6a</i> and <i>Rhox6</i> and <i>9</i> expression, respectively. …”
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